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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q1 2021

Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
218
No complete 13F data for Q4 2020
Shares held
80.5M
No complete 13F data for Q4 2020
Total value
$4.60B
No complete 13F data for Q4 2020

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2021: 218 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ1 2021: $4.60B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q1 2021

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc..

Livermore's 13F data starts with Q1 2021, so Q1 2021 has no change from the previous quarter.

Institutions holding DNLI in Q1 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Hillsdale Investment Management Inc.18,200$1.04M0.09%––
Handelsbanken Fonder AB18,200$1.04M0.01%––
Ironwood Investment Management LLC19,520$1.11M0.59%––
Duality Advisers, LP19,642$1.12M0.10%––
Public Employees Retirement System of Ohio20,201$1.15M0.00%––
Virginia Retirement Systems Et Al20,600$1.18M0.01%––
Jefferies Group LLC21,100$1.20M0.03%––
PDT Partners, LLC22,265$1.27M0.09%––
Mackay Shields LLC22,400$1.28M0.01%––
Arizona State Retirement System22,690$1.30M0.01%––
Allianz Asset Management GmbH23,455$1.34M0.00%––
University of Texas/Texas Am Investment Managment Co23,629$1.35M0.79%––
State Board of Administration of Florida Retirement System23,815$1.36M0.00%––
Concentric Wealth Management, LLC24,438$1.40M0.46%––
MetLife Investment Management24,764$1.41M0.01%––
SEI Investments Co19,730$1.43M0.00%––
Gotham Asset Management, LLC25,241$1.44M0.06%––
Skandinaviska Enskilda Banken AB (publ)26,100$1.49M0.01%––
STRS Ohio26,600$1.52M0.01%––
Invesco Ltd.26,653$1.52M0.00%––
Parallax Volatility Advisers, L.P.26,777$1.53M0.01%––
SG Americas Securities, LLC27,178$1.55M0.01%––
Voya Investment Management LLC27,573$1.57M0.00%––
Voloridge Investment Management, LLC27,958$1.60M0.01%––
Erste Asset Management GmbH30,600$1.66M0.04%––
UBS Group AG30,229$1.73M0.00%––
Platinum Investment Management Ltd30,791$1.76M0.04%––
ProShare Advisors LLC33,577$1.92M0.01%––
Royal Bank of Canada35,981$2.06M0.00%––
Manufacturers Life Insurance Company, The36,046$2.06M0.00%––
DekaBank Deutsche Girozentrale37,900$2.08M0.01%––
Connor, Clark & Lunn Investment Management Ltd.37,906$2.16M0.01%––
Victory Capital Management Inc38,355$2.19M0.00%––
American International Group, Inc.38,523$2.20M0.01%––
Tudor Investment Corp Et Al39,106$2.23M0.05%––
Ensign Peak Advisors, Inc41,642$2.38M0.01%––
Macquarie Group Ltd42,932$2.45M0.00%––
Legal & General Group Plc43,550$2.49M0.00%––
First Trust Advisors LP43,771$2.50M0.00%––
Parametric Portfolio Associates LLC43,819$2.50M0.00%––
Jacobs Levy Equity Management, Inc45,296$2.59M0.02%––
Russell Investments Group, Ltd.47,966$2.73M0.00%––
State of New Jersey Common Pension Fund D49,271$2.81M0.01%––
Rafferty Asset Management, LLC51,505$2.94M0.02%––
Bank of America Corp51,771$2.96M0.00%––
Capital Fund Management S.A.52,319$2.99M0.10%––
AIA Group Ltd54,375$3.10M0.45%––
Edmond de Rothschild Holding S.A.57,000$3.25M0.09%––
Man Group plc58,525$3.34M0.01%––
Deutsche Bank AG58,789$3.36M0.00%––
Balyasny Asset Management LLC68,102$3.89M0.02%––
Citigroup Inc69,774$3.98M0.00%––
Rhumbline Advisers71,575$4.09M0.01%––
Putnam Investments LLC71,620$4.09M0.01%––
JPMorgan Chase & Co75,181$4.29M0.00%––
Cubist Systematic Strategies, LLC83,641$4.78M0.06%––
Arrowstreet Capital, Limited Partnership85,607$4.89M0.01%––
AQR Capital Management LLC86,624$4.95M0.01%––
Baker Bros. Advisors LP88,738$5.07M0.02%––
State of Wisconsin Investment Board89,700$5.12M0.01%––
Barclays PLC89,773$5.13M0.00%––
California State Teachers Retirement System94,826$5.42M0.01%––
Alliancebernstein L.P.96,600$5.52M0.00%––
Integral Health Asset Management, LLC97,000$5.54M1.58%––
Hamilton Lane Advisors LLC97,370$5.56M1.81%––
Marshall Wace, LLP99,518$5.68M0.03%––
Mark Asset Management LP111,919$6.39M1.01%––
Wells Fargo & Company116,124$6.63M0.00%––
Federated Hermes, Inc.129,960$7.42M0.01%––
Teachers Retirement System of the State of Kentucky138,296$7.90M0.08%––
Natixis139,698$7.98M0.03%––
TD Asset Management Inc140,837$8.04M0.01%––
New York State Common Retirement Fund146,903$8.39M0.01%––
Tekla Capital Management LLC150,086$8.57M0.29%––
California Public Employees Retirement System163,332$9.33M0.01%––
AXA S.A.176,978$10.1M0.03%––
Swiss National Bank178,100$10.2M0.01%––
Prudential Financial Inc187,944$10.7M0.02%––
D. E. Shaw & Co., Inc.206,162$11.8M0.01%––
Caas Capital Management LP232,796$13.3M0.40%––
Citadel Advisors LLC240,784$13.7M0.01%––
Bank of New York Mellon Corp261,364$14.9M0.00%––
Renaissance Technologies LLC265,900$15.2M0.02%––
Marshall Wace North America L.P.275,926$15.8M0.07%––
Nuveen Asset Management, LLC277,621$15.9M0.01%––
American Century Companies Inc291,242$16.6M0.01%––
UBS Asset Management Americas Inc298,284$17.0M0.01%––
Eagle Asset Management Inc317,862$17.8M0.08%––
Euclidean Capital LLC323,749$18.5M6.19%––
Principal Financial Group Inc337,567$19.3M0.01%––
Mitsubishi UFJ Trust & Banking Corp366,840$20.9M0.05%––
Jennison Associates LLC374,512$21.4M0.02%––
Dimensional Fund Advisors LP421,202$24.0M0.01%––
Two Sigma Advisers, LP451,300$25.8M0.07%––
Morgan Stanley462,160$26.4M0.00%––
Wasatch Advisors Inc478,442$27.3M0.12%––
Pictet Asset Management Ltd488,499$27.9M0.03%––
Two Sigma Investments, LP496,703$28.4M0.09%––
Artal Group S.A.500,000$28.6M0.60%––
Charles Schwab Investment Management Inc565,516$32.3M0.01%––