Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2026
Institutional positions in Definium Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 248
- +42 vs. Q4 2025
- Shares held
- 78.1M
- +12.8M (+19.6%) vs. Q4 2025
- Total value
- $1.47B
- +$600.8M (+68.7%) vs. Q4 2025
- New holders
- 69
- 82 more added
- Sold out
- 27
- 53 more reduced
3 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| TSFG, LLC | 6 | $0 | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 1 | $1 | 0.00% | 00.0% | Unchanged |
| Keating Financial Advisory Services, Inc. | 1 | $19 | 0.00% | −6−85.7% | Reduced |
| CoreCap Advisors, LLC | 5 | $95 | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 7 | $125 | 0.00% | −133−95.0% | Reduced |
| Essential Partners LLC | 21 | $397 | 0.00% | 00.0% | Unchanged |
| Pinnacle Wealth Planning Services, Inc. | 25 | $472 | 0.00% | 00.0% | Unchanged |
| Rachor Investment Advisory Services, LLC | 25 | $473 | 0.00% | 00.0% | Unchanged |
| Vanguard National Trust Co | 27 | $510 | 0.00% | +27 | New |
| Robbins Farley LLC | 28 | $530 | 0.00% | 00.0% | Unchanged |
| Benson Wealth Management INC | 30 | $567 | 0.00% | +30 | New |
| Chesapeake Asset Management LLC | 33 | $623 | 0.00% | 00.0% | Unchanged |
| RMG Wealth Management LLC | 30 | $642 | 0.00% | +30 | New |
| Sofos Investments, Inc. | 35 | $662 | 0.00% | 00.0% | Unchanged |
| Plante Moran Financial Advisors, LLC | 36 | $680 | 0.00% | 00.0% | Unchanged |
| Anfield Capital Management, LLC | 36 | $680 | 0.00% | +36 | New |
| Sunbelt Securities, Inc. | 44 | $832 | 0.00% | 00.0% | Unchanged |
| Optiver Holding B.V. | 49 | $926 | 0.00% | −74−60.2% | Reduced |
| Louisbourg Investments Inc. | 52 | $983 | 0.00% | +52 | New |
| Activest Wealth Management | 66 | $1.25K | 0.00% | 00.0% | Unchanged |
| MH & Associates Securities Management Corp | 66 | $1.25K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 98 | $1.85K | 0.00% | +7+7.7% | Added |
| NBC Securities, Inc. | 100 | $1.89K | 0.00% | 00.0% | Unchanged |
| HighMark Wealth Management LLC | 100 | $1.89K | 0.00% | 00.0% | Unchanged |
| MAI Capital Management | 103 | $1.95K | 0.00% | +44+74.6% | Added |
| Allworth Financial LP | 127 | $2.40K | 0.00% | −21−14.2% | Reduced |
| Sankala Group LLC | 141 | $2.56K | 0.00% | −250−63.9% | Reduced |
| Salem Investment Counselors Inc | 150 | $2.83K | 0.00% | +150 | New |
| Northwestern Mutual Wealth Management Co | 155 | $2.93K | 0.00% | −30−16.2% | Reduced |
| Strategic Wealth Partners, Ltd. | 166 | $3.14K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 180 | $3.22K | 0.00% | +180 | New |
| Atlantic Edge Private Wealth Management, LLC | 193 | $3.65K | 0.00% | 00.0% | Unchanged |
| Smartleaf Asset Management LLC | 215 | $3.76K | 0.00% | +215 | New |
| Federated Hermes, Inc. | 207 | $3.91K | 0.00% | +140+209.0% | Added |
| Parallel Advisors, LLC | 232 | $4.40K | 0.00% | 00.0% | Unchanged |
| Ancora Advisors, LLC | 251 | $4.74K | 0.00% | +251 | New |
| Rothschild Investment LLC | 292 | $5.52K | 0.00% | +5+1.7% | Added |
| EverSource Wealth Advisors, LLC | 295 | $5.58K | 0.00% | +41+16.1% | Added |
| Western Pacific Wealth Management, LP | 333 | $6.29K | 0.01% | +333 | New |
| Meeder Asset Management Inc | 353 | $6.67K | 0.00% | +353 | New |
| NVWM, LLC | 416 | $7.86K | 0.00% | 00.0% | Unchanged |
| Private Wealth Management Group, LLC | 450 | $8.51K | 0.00% | +450 | New |
| SRS Capital Advisors, Inc. | 466 | $8.81K | 0.00% | −13−2.7% | Reduced |
| Larson Financial Group LLC | 535 | $10.1K | 0.00% | 00.0% | Unchanged |
| Harbour Investments, Inc. | 556 | $10.5K | 0.00% | +556 | New |
| Massmutual Trust Co FSB | 568 | $10.7K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 567 | $11.7K | 0.00% | +110+24.1% | Added |
| Los Angeles Capital Management LLC | 618 | $11.7K | 0.00% | +618 | New |
| Kemnay Advisory Services Inc. | 806 | $15.2K | 0.00% | +806 | New |
| First Horizon Corp | 962 | $18.2K | 0.00% | +119+14.1% | Added |
| Bullock Wealth Management Group | 907 | $18.7K | 0.01% | −287−24.0% | Reduced |
| Stone House Investment Management, LLC | 1,000 | $18.9K | 0.00% | 00.0% | Unchanged |
| Opal Wealth Advisors, LLC | 1,101 | $20.8K | 0.00% | +1,101 | New |
| GAMMA Investing LLC | 1,111 | $21.0K | 0.00% | +81+7.9% | Added |
| High Note Wealth, LLC | 1,500 | $28.4K | 0.01% | 00.0% | Unchanged |
| National Bank of Canada | 1,708 | $32.3K | 0.00% | −159−8.5% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,812 | $34.2K | 0.00% | +433+31.4% | Added |
| TD Waterhouse Canada Inc. | 1,802 | $37.1K | 0.00% | +270+17.6% | Added |
| Crewe Advisors LLC | 1,999 | $37.8K | 0.00% | 00.0% | Unchanged |
| KBC Group NV | 2,172 | $41.0K | 0.00% | +2,172 | New |
| GF Fund Management Co. Ltd. | 2,213 | $41.8K | 0.00% | +278+14.4% | Added |
| UBS Asset Management Americas Inc | 2,413 | $45.6K | 0.00% | +1,519+169.9% | Added |
| Sterling Capital Management LLC | 2,443 | $46.2K | 0.00% | −1,472−37.6% | Reduced |
| Advisory Services Network, LLC | 2,659 | $50.3K | 0.00% | +2,659 | New |
| Fifth Third Bancorp | 3,300 | $62.4K | 0.00% | 00.0% | Unchanged |
| Sound Income Strategies, LLC | 3,690 | $76.0K | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 4,036 | $76.3K | 0.01% | +4,021+26,806.7% | Added |
| Mirae Asset Global Investments Co., Ltd. | 5,200 | $98.3K | 0.00% | +5,200 | New |
| Walleye Trading LLC | 5,414 | $102.3K | 0.00% | +1,158+27.2% | Added |
| CWM, LLC | 5,600 | $105.8K | 0.00% | +248+4.6% | Added |
| Tower Research Capital LLC (TRC) | 7,305 | $138.1K | 0.00% | +2,971+68.6% | Added |
| Hollencrest Capital Management | 7,386 | $139.6K | 0.01% | −130−1.7% | Reduced |
| North Star Investment Management Corp. | 7,571 | $143.1K | 0.01% | +870+13.0% | Added |
| The PNC Financial Services Group, Inc. | 7,620 | $144.0K | 0.00% | +532+7.5% | Added |
| Ameritas Investment Partners, Inc. | 7,641 | $144.4K | 0.00% | 00.0% | Unchanged |
| Swiss Life Asset Management Ltd | 17,745 | $187.0K | 0.00% | +17,745 | New |
| Sharpepoint LLC | 10,000 | $189.0K | 0.11% | −135−1.3% | Reduced |
| King Wealth | 10,000 | $189.0K | 0.02% | 00.0% | Unchanged |
| CIBC World Markets Inc. | 10,049 | $189.9K | 0.00% | +10,049 | New |
| Commonwealth Equity Services, LLC | 10,251 | $193.7K | 0.00% | −3,360−24.7% | Reduced |
| Teacher Retirement System of Texas | 10,300 | $194.7K | 0.00% | −1,497−12.7% | Reduced |
| Verition Fund Management LLC | 10,384 | $196.3K | 0.00% | −121,879−92.1% | Reduced |
| Schonfeld Strategic Advisors LLC | 10,412 | $196.8K | 0.00% | −20,044−65.8% | Reduced |
| SG Americas Securities, LLC | 10,493 | $198.0K | 0.00% | +10,493 | New |
| Advisor Group Holdings, Inc. | 10,559 | $199.6K | 0.00% | +32+0.3% | Added |
| Dynamic Technology Lab Private Ltd | 10,880 | $205.6K | 0.03% | −12,084−52.6% | Reduced |
| RPS Advisory Solutions LLC | 11,355 | $214.6K | 0.12% | +11,355 | New |
| Chicago Partners Investment Group LLC | 9,307 | $214.8K | 0.00% | +9,307 | New |
| Sanctuary Advisors, LLC | 11,466 | $216.7K | 0.00% | +749+7.0% | Added |
| Diversify Wealth Management, LLC | 11,000 | $225.4K | 0.00% | +1,000+10.0% | Added |
| Bank of Montreal | 12,136 | $229.4K | 0.00% | +334+2.8% | Added |
| Twelve Points Wealth Management LLC | 12,245 | $231.4K | 0.05% | +1,600+15.0% | Added |
| Cinctive Capital Management LP | 12,551 | $237.2K | 0.02% | +12,551 | New |
| Stifel Financial Corp | 12,626 | $238.6K | 0.00% | +12,626 | New |
| Federation des caisses Desjardins du Quebec | 12,644 | $239.0K | 0.00% | +2,040+19.2% | Added |
| Money Concepts Capital Corp | 13,000 | $245.7K | 0.01% | 00.0% | Unchanged |
| Summit Trail Advisors, LLC | 13,000 | $245.7K | 0.00% | +13,000 | New |
| Magnetar Financial LLC | 13,178 | $249.1K | 0.00% | +13,178 | New |
| Steward Partners Investment Advisory, LLC | 13,240 | $250.2K | 0.00% | +12,240+1,224.0% | Added |
| Pictet Asset Management Holding SA | 13,295 | $251.3K | 0.00% | +13,295 | New |