Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2025
Institutional positions in Definium Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 196
- +15 vs. Q2 2025
- Shares held
- 39.7M
- −2.05M (−4.9%) vs. Q2 2025
- Total value
- $468.6M
- +$197.6M (+72.9%) vs. Q2 2025
- New holders
- 39
- 56 more added
- Sold out
- 24
- 48 more reduced
2 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Virtus Investment Advisers, Inc. | 15,587 | $183.8K | 0.05% | +2,706+21.0% | Added |
| Axq Capital, LP | 15,585 | $183.7K | 0.07% | +15,585 | New |
| FMR LLC | 15,558 | $183.4K | 0.00% | +1,771+12.8% | Added |
| BNP Paribas Arbitrage, SA | 15,320 | $180.6K | 0.00% | +6,903+82.0% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 15,117 | $178.2K | 0.00% | −485−3.1% | Reduced |
| Teacher Retirement System of Texas | 14,694 | $173.2K | 0.00% | −1,566−9.6% | Reduced |
| Commonwealth Equity Services, LLC | 14,550 | $172.0K | 0.00% | −1,905−11.6% | Reduced |
| Voya Investment Management LLC | 14,282 | $168.4K | 0.00% | −6,979−32.8% | Reduced |
| Bay Rivers Group | 14,001 | $165.1K | 0.07% | +2,383+20.5% | Added |
| Russell Investments Group, Ltd. | 13,703 | $161.6K | 0.00% | +9,886+259.0% | Added |
| Wealth Enhancement Advisory Services, LLC | 13,352 | $159.8K | 0.00% | −84−0.6% | Reduced |
| China Universal Asset Management Co., Ltd. | 13,337 | $157.2K | 0.01% | −1,838−12.1% | Reduced |
| Money Concepts Capital Corp | 13,000 | $153.3K | 0.01% | +13,000 | New |
| Rafferty Asset Management, LLC | 12,675 | $149.4K | 0.00% | +12,675 | New |
| HighTower Advisors, LLC | 12,643 | $149.1K | 0.00% | −32−0.3% | Reduced |
| Creative Planning | 11,909 | $140.4K | 0.00% | −54,188−82.0% | Reduced |
| Sanctuary Advisors, LLC | 11,665 | $137.5K | 0.00% | +40.0% | Added |
| Stoneridge Investment Partners LLC | 11,563 | $136.0K | 0.09% | +804+7.5% | Added |
| Bank of Montreal | 11,397 | $134.4K | 0.00% | −522−4.4% | Reduced |
| Advisor Group Holdings, Inc. | 11,602 | $126.5K | 0.00% | −5,849−33.5% | Reduced |
| Caxton Associates LLP | 10,645 | $125.5K | 0.00% | +10,645 | New |
| Diversify Wealth Management, LLC | 10,000 | $122.9K | 0.01% | 00.0% | Unchanged |
| SEI Investments Co | 10,415 | $122.8K | 0.00% | 00.0% | Unchanged |
| KLP Kapitalforvaltning AS | 10,400 | $122.6K | 0.00% | 00.0% | Unchanged |
| Dynamic Technology Lab Private Ltd | 10,352 | $122.0K | 0.02% | −4,271−29.2% | Reduced |
| Point72 Asia (Singapore) Pte. Ltd. | 10,222 | $120.5K | 0.02% | +10,222 | New |
| King Wealth | 10,000 | $118.0K | 0.01% | 00.0% | Unchanged |
| FNY Investment Advisers, LLC | 9,094 | $107.0K | 0.03% | +9,094 | New |
| Hollencrest Capital Management | 7,516 | $88.6K | 0.00% | +300+4.2% | Added |
| Ameritas Investment Partners, Inc. | 7,053 | $83.2K | 0.00% | 00.0% | Unchanged |
| North Star Investment Management Corp. | 6,701 | $79.0K | 0.01% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 5,594 | $69.1K | 0.00% | −63−1.1% | Reduced |
| Walleye Capital LLC | 5,737 | $67.6K | 0.00% | +5,737 | New |
| Point72 (DIFC) Ltd | 4,578 | $54.0K | 0.00% | +4,578 | New |
| CWM, LLC | 4,532 | $53.0K | 0.00% | +73+1.6% | Added |
| Sound Income Strategies, LLC | 3,681 | $46.0K | 0.00% | +3,681 | New |
| Sterling Capital Management LLC | 3,631 | $42.8K | 0.00% | +2,175+149.4% | Added |
| Fifth Third Bancorp | 3,359 | $39.6K | 0.00% | +3,300+5,593.2% | Added |
| Ameritas Advisory Services, LLC | 3,250 | $38.3K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 2,942 | $34.7K | 0.00% | +23+0.8% | Added |
| Amalgamated Bank | 2,781 | $33.0K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 2,450 | $28.9K | 0.00% | −6,406−72.3% | Reduced |
| BIT Capital GmbH | 2,245 | $26.5K | 0.00% | +2,245 | New |
| Crewe Advisors LLC | 1,999 | $23.6K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,637 | $19.3K | 0.00% | −240−12.8% | Reduced |
| National Bank of Canada | 1,591 | $18.7K | 0.00% | +170+12.0% | Added |
| Bullock Wealth Management Group | 1,194 | $14.7K | 0.01% | 00.0% | Unchanged |
| Stone House Investment Management, LLC | 1,000 | $11.8K | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 1,000 | $11.8K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 919 | $10.8K | 0.00% | −189−17.1% | Reduced |
| Point72 Europe (London) LLP | 815 | $9.61K | 0.00% | +815 | New |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 792 | $9.00K | 0.00% | +114+16.8% | Added |
| Advisory Services Network, LLC | 656 | $7.74K | 0.00% | +656 | New |
| Walleye Trading LLC | 562 | $6.63K | 0.00% | +562 | New |
| Harbour Investments, Inc. | 556 | $6.55K | 0.00% | 00.0% | Unchanged |
| Global Retirement Partners, LLC | 500 | $5.89K | 0.00% | +500 | New |
| Farther Finance Advisors, LLC | 457 | $5.39K | 0.00% | 00.0% | Unchanged |
| Massmutual Trust Co FSB | 432 | $5.09K | 0.00% | 00.0% | Unchanged |
| NVWM, LLC | 416 | $4.91K | 0.00% | 00.0% | Unchanged |
| Tortoise Investment Management, LLC | 400 | $4.72K | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 351 | $4.14K | 0.00% | +351 | New |
| Rothschild Investment LLC | 273 | $3.22K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 242 | $3.00K | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 232 | $2.74K | 0.00% | −20−7.9% | Reduced |
| Optiver Holding B.V. | 218 | $2.57K | 0.00% | +218 | New |
| Atlantic Edge Private Wealth Management, LLC | 193 | $2.28K | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 166 | $1.96K | 0.00% | −467−73.8% | Reduced |
| CIBC Private Wealth Group, LLC | 151 | $1.78K | 0.00% | −333−68.8% | Reduced |
| GWM Advisors LLC | 142 | $1.67K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 105 | $1.24K | 0.00% | −277−72.5% | Reduced |
| EverSource Wealth Advisors, LLC | 104 | $1.23K | 0.00% | +14+15.6% | Added |
| NBC Securities, Inc. | 100 | $1.18K | 0.00% | −500−83.3% | Reduced |
| HighMark Wealth Management LLC | 100 | $1.18K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 85 | $1.00K | 0.00% | 00.0% | Unchanged |
| Activest Wealth Management | 66 | $778 | 0.00% | 00.0% | Unchanged |
| Guerra Advisors Inc | 66 | $778 | 0.00% | +66 | New |
| Principal Securities, Inc. | 58 | $684 | 0.00% | 00.0% | Unchanged |
| Tradewinds Capital Management, LLC | 53 | $625 | 0.00% | 00.0% | Unchanged |
| Louisbourg Investments Inc. | 52 | $613 | 0.00% | 00.0% | Unchanged |
| Sofos Investments, Inc. | 48 | $566 | 0.00% | +48 | New |
| Sunbelt Securities, Inc. | 44 | $519 | 0.00% | +44 | New |
| Plante Moran Financial Advisors, LLC | 36 | $424 | 0.00% | 00.0% | Unchanged |
| Anfield Capital Management, LLC | 36 | $424 | 0.00% | 00.0% | Unchanged |
| Chesapeake Asset Management LLC | 33 | $389 | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 29 | $342 | 0.00% | +12+70.6% | Added |
| Robbins Farley LLC | 28 | $331 | 0.00% | 00.0% | Unchanged |
| MAI Capital Management | 10 | $118 | 0.00% | 00.0% | Unchanged |
| CNB Bank | 10 | $118 | 0.00% | 00.0% | Unchanged |
| NBT Bank N A | 6 | $71 | 0.00% | 00.0% | Unchanged |
| Strategic Investment Solutions, Inc. | 6 | $71 | 0.00% | 00.0% | Unchanged |
| Grey Fox Wealth Advisors, LLC | 6 | $71 | 0.00% | +6 | New |
| CoreCap Advisors, LLC | 5 | $59 | 0.00% | 00.0% | Unchanged |
| Essential Partners LLC | 4 | $47 | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 2 | $24 | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 1 | $1 | 0.00% | 00.0% | Unchanged |
| TSFG, LLC | 6 | $0 | 0.00% | 00.0% | Unchanged |
| Woodline Partners LP | 0 | $0 | 0.00% | −502,198−100.0% | Sold out |
| Oppenheimer & Co Inc | 0 | $0 | 0.00% | −98,336−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −38,937−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −32,402−100.0% | Sold out |