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Definium Therapeutics, Inc.

DFTX
Exchange
Nasdaq
Industry
Medicinal Chemicals & Botanical Products
SEC CIK
0001813814

In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.

Q3 2025 vs. Q2 2025

How the institutions holding Definium Therapeutics, Inc. changed between Q2 2025 and Q3 2025.

All holders in Q3 2025All holders in Q2 2025

13F holders of DFTX: Q2 2025 compared with Q3 2025
MeasureQ2 2025Of which not filed for Q3 2025Q3 2025Change
Holders1832196+15
Shares41.8M11.1K39.7M−2.05M (−4.9%)
Value$271.0M$72.3K$468.6M+$197.6M (+72.9%)

2 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (39)

Institutions that held Definium Therapeutics, Inc. at the end of Q3 2025 but not at the end of Q2 2025.

Institutions new to DFTX in Q3 2025
InstitutionSharesValue% of portfolio
OrbiMed Advisors LLC367,824$4.34M0.10%
Adage Capital Partners GP, L.L.C.300,000$3.54M0.01%
Point72 Asset Management, L.P.224,300$2.64M0.01%
Boxer Capital Management, LLC163,500$1.93M0.61%
CenterBook Partners LP159,421$1.88M0.09%
Cubist Systematic Strategies, LLC108,214$1.28M0.02%
Two Sigma Advisers, LP81,483$960.7K0.00%
Royce & Associates LP81,024$955.3K0.01%
PFM Health Sciences, LP75,138$885.9K0.08%
Wolverine Trading, LLC60,250$725.4K0.01%
HRT Financial LP57,565$678.0K0.00%
Gsa Capital Partners LLP55,489$654.0K0.05%
Fox Run Management, L.L.C.51,692$609.4K0.10%
Schonfeld Strategic Advisors LLC35,510$418.7K0.00%
Virtu Financial LLC32,184$379.0K0.02%
Sender Co & Partners, Inc.25,906$305.4K0.12%
Scientech Research LLC24,239$285.8K0.10%
Omers Administration Corp16,600$195.7K0.00%
Cetera Investment Advisers16,242$191.5K0.00%
Axq Capital, LP15,585$183.7K0.07%
Money Concepts Capital Corp13,000$153.3K0.01%
Rafferty Asset Management, LLC12,675$149.4K0.00%
Caxton Associates LLP10,645$125.5K0.00%
Point72 Asia (Singapore) Pte. Ltd.10,222$120.5K0.02%
FNY Investment Advisers, LLC9,094$107.0K0.03%
Walleye Capital LLC5,737$67.6K0.00%
Point72 (DIFC) Ltd4,578$54.0K0.00%
Sound Income Strategies, LLC3,681$46.0K0.00%
BIT Capital GmbH2,245$26.5K0.00%
Point72 Europe (London) LLP815$9.61K0.00%
Advisory Services Network, LLC656$7.74K0.00%
Walleye Trading LLC562$6.63K0.00%
Global Retirement Partners, LLC500$5.89K0.00%
Rockefeller Capital Management L.P.351$4.14K0.00%
Optiver Holding B.V.218$2.57K0.00%
Guerra Advisors Inc66$7780.00%
Sofos Investments, Inc.48$5660.00%
Sunbelt Securities, Inc.44$5190.00%
Grey Fox Wealth Advisors, LLC6$710.00%

Sold out (24)

Institutions that held Definium Therapeutics, Inc. at the end of Q2 2025 and filed for Q3 2025 without it.

Not filed for Q3 2025 yet (2)

Institutions that held Definium Therapeutics, Inc. at the end of Q2 2025 and haven't filed a 13F for Q3 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding DFTX in Q2 2025 that haven't filed for Q3 2025
InstitutionShares, Q2 2025Value, Q2 2025
Avantax Advisory Services, Inc.11,138$72.3K
Belmont Capital, LLC6$39