Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2025
Institutional positions in Definium Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 183
- −8 vs. Q1 2025
- Shares held
- 41.8M
- +639.6K (+1.6%) vs. Q1 2025
- Total value
- $271.0M
- +$30.5M (+12.7%) vs. Q1 2025
- New holders
- 18
- 57 more added
- Sold out
- 26
- 50 more reduced
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Arizona State Retirement System | 17,581 | $114.1K | 0.00% | +1,805+11.4% | Added |
| ExodusPoint Capital Management, LP | 17,877 | $116.0K | 0.00% | +17,877 | New |
| Boothbay Fund Management, LLC | 17,984 | $116.7K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 18,268 | $118.6K | 0.00% | −941−4.9% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 18,554 | $120.4K | 0.00% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 19,684 | $127.7K | 0.00% | −3,787−16.1% | Reduced |
| AQR Capital Management LLC | 19,758 | $128.2K | 0.00% | +7,508+61.3% | Added |
| Mercer Global Advisors Inc | 19,852 | $128.8K | 0.00% | +272+1.4% | Added |
| Mitchell McLeod Pugh & Williams Inc | 20,000 | $129.8K | 0.02% | 00.0% | Unchanged |
| Voya Investment Management LLC | 21,261 | $138.0K | 0.00% | +146+0.7% | Added |
| Federation des caisses Desjardins du Quebec | 21,422 | $139.0K | 0.00% | −1,000−4.5% | Reduced |
| Blair William & Co | 22,218 | $144.2K | 0.00% | +9,718+77.7% | Added |
| Palumbo Wealth Management LLC | 24,043 | $156.0K | 0.05% | +1,415+6.3% | Added |
| Manufacturers Life Insurance Company, The | 27,568 | $178.9K | 0.00% | +204+0.7% | Added |
| Janus Henderson Group PLC | 28,000 | $181.9K | 0.00% | 00.0% | Unchanged |
| Rathbone Brothers plc | 28,200 | $183.0K | 0.00% | 00.0% | Unchanged |
| Polar Asset Management Partners Inc. | 29,300 | $190.2K | 0.00% | +29,300 | New |
| Moloney Securities Asset Management, LLC | 31,511 | $204.5K | 0.03% | −4,500−12.5% | Reduced |
| XTX Topco Ltd | 32,402 | $210.3K | 0.01% | +2,858+9.7% | Added |
| Caxton Corp | 34,073 | $221.1K | 2.24% | 00.0% | Unchanged |
| Fore Capital, LLC | 35,000 | $227.2K | 0.45% | −5,000−12.5% | Reduced |
| Price T Rowe Associates Inc | 36,331 | $236.0K | 0.00% | +5,386+17.4% | Added |
| Persistent Asset Partners Ltd | 36,642 | $237.8K | 0.21% | +36,642 | New |
| Citigroup Inc | 37,333 | $242.3K | 0.00% | −33,842−47.5% | Reduced |
| Intech Investment Management LLC | 37,686 | $244.6K | 0.00% | −17,304−31.5% | Reduced |
| Invesco Ltd. | 38,463 | $249.6K | 0.00% | −637−1.6% | Reduced |
| Balyasny Asset Management LLC | 38,937 | $252.7K | 0.00% | −130,621−77.0% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 41,261 | $267.8K | 0.00% | −2,289−5.3% | Reduced |
| UBS Asset Management Americas Inc | 42,129 | $273.4K | 0.00% | −3,492−7.7% | Reduced |
| Wells Fargo & Company | 47,717 | $309.7K | 0.00% | +10,301+27.5% | Added |
| Deutsche Bank AG | 47,989 | $311.4K | 0.00% | −11,237−19.0% | Reduced |
| JPMorgan Chase & Co | 48,487 | $314.7K | 0.00% | +2,342+5.1% | Added |
| MetLife Investment Management | 49,196 | $319.3K | 0.00% | 00.0% | Unchanged |
| Cerity Partners LLC | 49,650 | $322.2K | 0.00% | +1,165+2.4% | Added |
| Kestra Private Wealth Services, LLC | 50,140 | $325.4K | 0.00% | −66−0.1% | Reduced |
| Scotia Capital Inc. | 53,931 | $350.2K | 0.00% | −44−0.1% | Reduced |
| Two Sigma Investments, LP | 56,478 | $366.5K | 0.00% | −2,744−4.6% | Reduced |
| Legal & General Group Plc | 56,703 | $368.0K | 0.00% | −590−1.0% | Reduced |
| California State Teachers Retirement System | 57,288 | $371.8K | 0.00% | −1,210−2.1% | Reduced |
| D. E. Shaw & Co., Inc. | 58,764 | $381.4K | 0.00% | −4,485−7.1% | Reduced |
| Ikarian Capital, LLC | 62,691 | $406.9K | 0.13% | 00.0% | Unchanged |
| Creative Planning | 66,097 | $429.0K | 0.00% | +1,655+2.6% | Added |
| LPL Financial LLC | 68,489 | $444.5K | 0.00% | +1,056+1.6% | Added |
| DRW Securities, LLC | 69,426 | $450.6K | 0.03% | +19,426+38.9% | Added |
| Alliancebernstein L.P. | 74,830 | $485.6K | 0.00% | −750−1.0% | Reduced |
| Simplex Trading, LLC | 87,951 | $570.0K | 0.02% | +40,095+83.8% | Added |
| StemPoint Capital LP | 90,852 | $589.6K | 0.19% | +90,852 | New |
| Royal Bank of Canada | 97,129 | $629.0K | 0.00% | +31,892+48.9% | Added |
| Oppenheimer & Co Inc | 98,336 | $638.2K | 0.01% | +27,221+38.3% | Added |
| Data Collective IV GP, LLC | 100,350 | $651.3K | 0.50% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 102,847 | $667.5K | 0.00% | −89,348−46.5% | Reduced |
| AdvisorShares Investments LLC | 109,593 | $711.3K | 0.13% | −10,000−8.4% | Reduced |
| Swiss National Bank | 115,100 | $747.0K | 0.00% | +8,500+8.0% | Added |
| Rhumbline Advisers | 115,296 | $748.3K | 0.00% | +6,839+6.3% | Added |
| Bank of America Corp | 119,214 | $773.7K | 0.00% | +30,992+35.1% | Added |
| Jane Street Group, LLC | 128,315 | $832.8K | 0.00% | +54,326+73.4% | Added |
| Diadema Partners LP | 158,536 | $1.03M | 0.64% | +158,536 | New |
| Susquehanna International Group, LLP | 169,325 | $1.10M | 0.00% | −175,879−50.9% | Reduced |
| Barclays PLC | 175,233 | $1.14M | 0.00% | +55,660+46.5% | Added |
| Citadel Advisors LLC | 178,604 | $1.16M | 0.00% | −234,786−56.8% | Reduced |
| Millennium Management LLC | 183,400 | $1.19M | 0.00% | +183,400 | New |
| Nuveen, LLC | 239,842 | $1.56M | 0.00% | −26,209−9.9% | Reduced |
| Bank of New York Mellon Corp | 240,739 | $1.56M | 0.00% | +40,542+20.3% | Added |
| Wellington Management Group LLP | 261,953 | $1.70M | 0.00% | +36,025+15.9% | Added |
| Rosalind Advisors, Inc. | 420,000 | $2.73M | 1.32% | 00.0% | Unchanged |
| Woodline Partners LP | 502,198 | $3.26M | 0.02% | −503,000−50.0% | Reduced |
| UBS Group AG | 514,445 | $3.34M | 0.00% | +406,419+376.2% | Added |
| Charles Schwab Investment Management Inc | 598,212 | $3.88M | 0.00% | +34,908+6.2% | Added |
| Northern Trust Corp | 599,242 | $3.89M | 0.00% | −43,541−6.8% | Reduced |
| Tang Capital Management LLC | 600,200 | $3.90M | 0.20% | +200,000+50.0% | Added |
| Morgan Stanley | 688,531 | $4.47M | 0.00% | +28,639+4.3% | Added |
| Ally Bridge Group (NY) LLC | 726,172 | $4.71M | 3.92% | +336,029+86.1% | Added |
| AWM Investment Company, Inc. | 1,215,662 | $7.89M | 0.88% | +7,500+0.6% | Added |
| Geode Capital Management, LLC | 1,733,454 | $11.3M | 0.00% | +66,663+4.0% | Added |
| State Street Corp | 1,805,893 | $11.7M | 0.00% | −36,321−2.0% | Reduced |
| Vanguard Group Inc | 1,813,996 | $11.8M | 0.00% | +47,449+2.7% | Added |
| Octagon Capital Advisors LP | 2,130,000 | $13.8M | 3.04% | −888,000−29.4% | Reduced |
| Deep Track Capital, LP | 2,500,000 | $16.2M | 0.52% | 00.0% | Unchanged |
| Driehaus Capital Management LLC | 3,092,658 | $20.1M | 0.16% | −258,747−7.7% | Reduced |
| Marshall Wace, LLP | 3,421,224 | $22.2M | 0.03% | +828,067+31.9% | Added |
| Blackstone Group Inc. | 3,587,479 | $23.3M | 0.10% | 00.0% | Unchanged |
| Commodore Capital LP | 5,000,000 | $32.5M | 2.29% | +475,000+10.5% | Added |
| BlackRock, Inc. | 5,802,139 | $37.7M | 0.00% | +86,426+1.5% | Added |
| Corebridge Financial, Inc. | 0 | $0 | 0.00% | −35,986−100.0% | Sold out |
| Janney Montgomery Scott LLC | 0 | $0 | 0.00% | −34,685−100.0% | Sold out |
| Clough Capital Partners L P | 0 | $0 | 0.00% | −33,900−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −32,836−100.0% | Sold out |
| Algert Global LLC | 0 | $0 | 0.00% | −24,770−100.0% | Sold out |
| Massar Capital Management, LP | 0 | $0 | 0.00% | −24,583−100.0% | Sold out |
| EntryPoint Capital, LLC | 0 | $0 | 0.00% | −22,708−100.0% | Sold out |
| Gruss & Co., LLC | 0 | $0 | 0.00% | −16,939−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −16,703−100.0% | Sold out |
| CIBC World Markets Corp | 0 | $0 | 0.00% | −16,299−100.0% | Sold out |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −15,048−100.0% | Sold out |
| Wolverine Trading, LLC | 0 | $0 | 0.00% | −13,236−100.0% | Sold out |
| Rafferty Asset Management, LLC | 0 | $0 | 0.00% | −13,773−100.0% | Sold out |
| Change Path, LLC | 0 | $0 | 0.00% | −11,455−100.0% | Sold out |
| Black Swift Group, LLC | 0 | $0 | 0.00% | −10,713−100.0% | Sold out |
| Walleye Trading LLC | 0 | $0 | 0.00% | −2,910−100.0% | Sold out |
| Kestra Advisory Services, LLC | 0 | $0 | 0.00% | −2,532−100.0% | Sold out |