Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2025
Institutional positions in Definium Therapeutics, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 191
- +18 vs. Q4 2024
- Shares held
- 41.2M
- −58.8K (−0.1%) vs. Q4 2024
- Total value
- $240.5M
- −$46.4M (−16.2%) vs. Q4 2024
- New holders
- 39
- 50 more added
- Sold out
- 21
- 46 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Clear Street Markets LLC | 13,911 | $81.4K | 0.06% | +13,911 | New |
| Rafferty Asset Management, LLC | 13,773 | $80.6K | 0.00% | +13,773 | New |
| Wealth Enhancement Advisory Services, LLC | 13,538 | $79.2K | 0.00% | −12−0.1% | Reduced |
| Diametric Capital, LP | 13,370 | $78.2K | 0.09% | −2,080−13.5% | Reduced |
| PEAK6 LLC | 13,002 | $76.1K | 0.00% | +4,907+60.6% | Added |
| HighTower Advisors, LLC | 12,676 | $74.2K | 0.00% | −353−2.7% | Reduced |
| Blair William & Co | 12,500 | $73.1K | 0.00% | +12,500 | New |
| AQR Capital Management LLC | 12,250 | $71.7K | 0.00% | −12,887−51.3% | Reduced |
| Avantax Advisory Services, Inc. | 11,597 | $67.8K | 0.00% | +418+3.7% | Added |
| Change Path, LLC | 11,455 | $67.0K | 0.00% | +11,455 | New |
| Tower Research Capital LLC (TRC) | 11,368 | $66.5K | 0.00% | +9,218+428.7% | Added |
| Sanctuary Advisors, LLC | 11,332 | $66.3K | 0.00% | +330+3.0% | Added |
| Sharpepoint LLC | 10,165 | $64.0K | 0.06% | 00.0% | Unchanged |
| Stoneridge Investment Partners LLC | 10,759 | $63.0K | 0.05% | 00.0% | Unchanged |
| Diversify Wealth Management, LLC | 10,000 | $63.0K | 0.00% | 00.0% | Unchanged |
| Black Swift Group, LLC | 10,713 | $62.7K | 0.01% | +10,713 | New |
| SEI Investments Co | 10,415 | $60.9K | 0.00% | 00.0% | Unchanged |
| KLP Kapitalforvaltning AS | 10,400 | $60.8K | 0.00% | 00.0% | Unchanged |
| King Wealth | 10,000 | $59.0K | 0.01% | 00.0% | Unchanged |
| North Star Investment Management Corp. | 9,401 | $55.0K | 0.00% | 00.0% | Unchanged |
| Capital Advisors Inc | 50,000 | $50.0K | 0.00% | +50,000 | New |
| Hollencrest Capital Management | 7,216 | $42.2K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 7,053 | $41.3K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 5,397 | $31.6K | 0.00% | −5,234−49.2% | Reduced |
| TD Waterhouse Canada Inc. | 4,996 | $27.5K | 0.00% | +661+15.2% | Added |
| Larson Financial Group LLC | 2,932 | $17.2K | 0.00% | +2,932 | New |
| Walleye Trading LLC | 2,910 | $17.0K | 0.00% | +2,910 | New |
| Amalgamated Bank | 2,781 | $16.0K | 0.00% | +290+11.6% | Added |
| CWM, LLC | 2,663 | $16.0K | 0.00% | +1,195+81.4% | Added |
| Mirae Asset Global Investments Co., Ltd. | 2,454 | $15.2K | 0.00% | +10+0.4% | Added |
| Kestra Advisory Services, LLC | 2,532 | $14.8K | 0.00% | +2,532 | New |
| Nisa Investment Advisors, LLC | 2,433 | $14.2K | 0.00% | +2,229+1,092.6% | Added |
| EMC Capital Management | 2,575 | $14.0K | 0.01% | 00.0% | Unchanged |
| Crewe Advisors LLC | 1,999 | $11.7K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,877 | $11.0K | 0.00% | +337+21.9% | Added |
| Russell Investments Group, Ltd. | 1,814 | $10.6K | 0.00% | −352−16.3% | Reduced |
| National Bank of Canada | 1,421 | $8.31K | 0.00% | −126−8.1% | Reduced |
| Versant Capital Management, Inc | 1,137 | $6.65K | 0.00% | +1,137 | New |
| Bullock Wealth Management Group | 1,194 | $6.62K | 0.00% | 00.0% | Unchanged |
| IFP Advisors, Inc | 984 | $5.94K | 0.00% | +984 | Added |
| Steward Partners Investment Advisory, LLC | 1,000 | $5.85K | 0.00% | +100+11.1% | Added |
| Stone House Investment Management, LLC | 1,000 | $5.85K | 0.00% | +1,000 | New |
| Farther Finance Advisors, LLC | 994 | $5.51K | 0.00% | +93+10.3% | Added |
| GAMMA Investing LLC | 693 | $4.05K | 0.00% | +587+553.8% | Added |
| Massmutual Trust Co FSB | 567 | $3.32K | 0.00% | +567 | New |
| Caitong International Asset Management Co., Ltd | 559 | $3.27K | 0.00% | +559 | New |
| NBC Securities, Inc. | 600 | $3.00K | 0.00% | +600 | New |
| NVWM, LLC | 416 | $2.43K | 0.00% | 00.0% | Unchanged |
| Tortoise Investment Management, LLC | 400 | $2.34K | 0.00% | 00.0% | Unchanged |
| Skopos Labs, Inc. | 382 | $2.23K | 0.00% | +382 | New |
| Harbour Investments, Inc. | 356 | $2.08K | 0.00% | 00.0% | Unchanged |
| CIBC Private Wealth Group, LLC | 423 | $2.07K | 0.00% | 00.0% | Unchanged |
| CarsonAllaria Wealth Management, Ltd. | 325 | $1.90K | 0.00% | +325 | New |
| SBI Securities Co., Ltd. | 306 | $1.79K | 0.00% | +110+56.1% | Added |
| SRS Capital Advisors, Inc. | 264 | $1.54K | 0.00% | −12−4.3% | Reduced |
| Continuum Advisory, LLC | 239 | $1.40K | 0.00% | 00.0% | Unchanged |
| Atlantic Edge Private Wealth Management, LLC | 193 | $1.13K | 0.00% | +193 | New |
| Daiwa Securities Group Inc. | 242 | $1.00K | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 142 | $831 | 0.00% | −6−4.1% | Reduced |
| Pandora Wealth, Inc. | 131 | $766 | 0.00% | +131 | New |
| Northwestern Mutual Wealth Management Co | 100 | $585 | 0.00% | −368−78.6% | Reduced |
| HighMark Wealth Management LLC | 100 | $585 | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 87 | $509 | 0.00% | +13+17.6% | Added |
| Allworth Financial LP | 69 | $444 | 0.00% | 00.0% | Unchanged |
| Activest Wealth Management | 66 | $386 | 0.00% | 00.0% | Unchanged |
| Fifth Third Bancorp | 59 | $345 | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 56 | $328 | 0.00% | +43+330.8% | Added |
| Tradewinds Capital Management, LLC | 53 | $311 | 0.00% | 00.0% | Unchanged |
| Louisbourg Investments Inc. | 52 | $304 | 0.00% | 00.0% | Unchanged |
| TD Capital Management LLC | 39 | $228 | 0.00% | +39 | New |
| Plante Moran Financial Advisors, LLC | 36 | $211 | 0.00% | 00.0% | Unchanged |
| Anfield Capital Management, LLC | 36 | $211 | 0.00% | 00.0% | Unchanged |
| TruNorth Capital Management, LLC | 33 | $193 | 0.00% | 00.0% | Unchanged |
| Chesapeake Asset Management LLC | 33 | $193 | 0.00% | 00.0% | Unchanged |
| Robbins Farley LLC | 28 | $164 | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 19 | $111 | 0.00% | 00.0% | Unchanged |
| Coldstream Capital Management Inc | 16 | $94 | 0.00% | +16 | New |
| Ameriflex Group, Inc. | 13 | $76 | 0.00% | 00.0% | Unchanged |
| Harbor Investment Advisory, LLC | 13 | $76 | 0.00% | +13 | New |
| Boston Private Wealth LLC | 11 | $64 | 0.00% | +11 | New |
| MAI Capital Management | 10 | $59 | 0.00% | 00.0% | Unchanged |
| CNB Bank | 10 | $59 | 0.00% | 00.0% | Unchanged |
| NBT Bank N A | 6 | $35 | 0.00% | 00.0% | Unchanged |
| Belmont Capital, LLC | 6 | $35 | 0.00% | 00.0% | Unchanged |
| Strategic Investment Solutions, Inc. | 6 | $35 | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 5 | $29 | 0.00% | 00.0% | Unchanged |
| Hexagon Capital Partners LLC | 4 | $23 | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 3 | $18 | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 2 | $12 | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 1 | $1 | 0.00% | 00.0% | Unchanged |
| TSFG, LLC | 24 | $0 | 0.00% | 00.0% | Unchanged |
| Tri Locum Partners LP | 0 | $0 | 0.00% | −820,793−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −185,721−100.0% | Sold out |
| Allostery Investments LP | 0 | $0 | 0.00% | −130,000−100.0% | Sold out |
| BIT Capital GmbH | 0 | $0 | 0.00% | −63,405−100.0% | Sold out |
| ADAR1 Capital Management, LLC | 0 | $0 | 0.00% | −25,000−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −24,650−100.0% | Sold out |
| SG Americas Securities, LLC | 0 | $0 | 0.00% | −24,406−100.0% | Sold out |
| Corton Capital Inc. | 0 | $0 | 0.00% | −14,416−100.0% | Sold out |
| Foundations Investment Advisors, LLC | 0 | $0 | 0.00% | −13,100−100.0% | Sold out |