Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2024
Institutional positions in Definium Therapeutics, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 152
- +18 vs. Q1 2024
- Shares held
- 41.5M
- +6.72M (+19.3%) vs. Q1 2024
- Total value
- $299.3M
- −$27.9M (−8.5%) vs. Q1 2024
- New holders
- 45
- 39 more added
- Sold out
- 27
- 24 more reduced
1 institution that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q2 2024
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q1 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Man Group plc | 32,062 | $231.2K | 0.00% | −80,115−71.4% | Reduced |
| Bank of Montreal | 33,133 | $240.2K | 0.00% | +33,133 | New |
| JPMorgan Chase & Co | 34,198 | $246.6K | 0.00% | +30,682+872.6% | Added |
| Cubist Systematic Strategies, LLC | 35,508 | $256.0K | 0.00% | +6,890+24.1% | Added |
| Invesco Ltd. | 36,441 | $262.7K | 0.00% | +36,441 | New |
| Deutsche Bank AG | 36,690 | $264.5K | 0.00% | +31,077+553.7% | Added |
| Corebridge Financial, Inc. | 38,733 | $279.7K | 0.00% | +38,733 | New |
| Group One Trading, L.P. | 44,365 | $319.9K | 0.01% | +8,007+22.0% | Added |
| Barclays PLC | 44,827 | $323.2K | 0.00% | +35,680+390.1% | Added |
| Boothbay Fund Management, LLC | 46,221 | $333.3K | 0.01% | −38,403−45.4% | Reduced |
| LPL Financial LLC | 46,265 | $333.6K | 0.00% | +2,538+5.8% | Added |
| Kestra Private Wealth Services, LLC | 51,339 | $370.2K | 0.01% | 00.0% | Unchanged |
| Legal & General Group Plc | 53,233 | $383.8K | 0.00% | +53,233 | New |
| Scotia Capital Inc. | 53,951 | $389.7K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 56,300 | $405.9K | 0.00% | +56,300 | New |
| UBS Group AG | 56,488 | $407.3K | 0.00% | +32,104+131.7% | Added |
| Royal Bank of Canada | 66,898 | $483.0K | 0.00% | +26,279+64.7% | Added |
| Alpine Global Management, LLC | 68,176 | $491.5K | 0.09% | +68,176 | New |
| Goldman Sachs Group Inc | 69,514 | $501.2K | 0.00% | −338,486−83.0% | Reduced |
| Alliancebernstein L.P. | 75,330 | $543.1K | 0.00% | +75,330 | New |
| Bank of America Corp | 75,758 | $546.2K | 0.00% | +49,576+189.4% | Added |
| Wellington Management Group LLP | 76,570 | $552.1K | 0.00% | +21,505+39.1% | Added |
| UBS Asset Management Americas Inc | 78,079 | $562.9K | 0.00% | +78,079 | New |
| Jane Street Group, LLC | 78,273 | $564.3K | 0.00% | −294,186−79.0% | Reduced |
| Two Sigma Advisers, LP | 85,017 | $613.0K | 0.00% | +63,100+287.9% | Added |
| Rhumbline Advisers | 94,116 | $678.6K | 0.00% | +94,116 | New |
| Data Collective IV GP, LLC | 100,350 | $723.5K | 0.51% | 00.0% | Unchanged |
| Swiss National Bank | 110,900 | $799.6K | 0.00% | +110,900 | New |
| AdvisorShares Investments LLC | 124,166 | $877.9K | 0.15% | +14,659+13.4% | Added |
| Moloney Securities Asset Management, LLC | 135,311 | $975.6K | 0.14% | −26,650−16.5% | Reduced |
| Morgan Stanley | 157,981 | $1.14M | 0.00% | +47,019+42.4% | Added |
| Ikarian Capital, LLC | 162,481 | $1.17M | 0.37% | −135,000−45.4% | Reduced |
| Northern Trust Corp | 183,914 | $1.33M | 0.00% | +118,365+180.6% | Added |
| Nuveen Asset Management, LLC | 204,140 | $1.47M | 0.00% | +204,140 | New |
| Bank of New York Mellon Corp | 246,208 | $1.78M | 0.00% | +203,216+472.7% | Added |
| Tri Locum Partners LP | 382,055 | $2.75M | 0.70% | +2,459+0.6% | Added |
| Charles Schwab Investment Management Inc | 556,357 | $4.01M | 0.00% | +359,143+182.1% | Added |
| Two Sigma Investments, LP | 683,687 | $4.93M | 0.01% | −28,551−4.0% | Reduced |
| AWM Investment Company, Inc. | 833,000 | $6.01M | 0.81% | 00.0% | Unchanged |
| Ally Bridge Group (NY) LLC | 965,426 | $6.96M | 4.15% | −36,026−3.6% | Reduced |
| Woodline Partners LP | 1,001,250 | $7.22M | 0.07% | +671+0.1% | Added |
| Artal Group S.A. | 1,007,875 | $7.27M | 0.19% | +1,007,875 | New |
| Geode Capital Management, LLC | 1,514,769 | $10.9M | 0.00% | +1,125,365+289.0% | Added |
| Vanguard Group Inc | 1,741,403 | $12.6M | 0.00% | +1,178,482+209.4% | Added |
| State Street Corp | 1,805,047 | $13.0M | 0.00% | +1,686,143+1,418.1% | Added |
| Blackstone Group Inc. | 1,898,325 | $13.7M | 0.06% | +648,450+51.9% | Added |
| Octagon Capital Advisors LP | 2,153,000 | $15.5M | 2.56% | 00.0% | Unchanged |
| Marshall Wace, LLP | 2,160,203 | $15.6M | 0.02% | +161,659+8.1% | Added |
| Driehaus Capital Management LLC | 2,538,410 | $18.3M | 0.18% | −9,135−0.4% | Reduced |
| BlackRock Inc. | 5,384,030 | $38.8M | 0.00% | +4,589,718+577.8% | Added |
| Deep Track Capital, LP | 6,103,817 | $44.0M | 1.31% | −562,850−8.4% | Reduced |
| Commodore Capital LP | 7,145,888 | $51.5M | 3.52% | +1,312,555+22.5% | Added |
| Great Point Partners LLC | 0 | $0 | 0.00% | −2,000,000−100.0% | Sold out |
| Soleus Capital Management, L.P. | 0 | $0 | 0.00% | −750,237−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −388,202−100.0% | Sold out |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −300,000−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −269,596−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −207,253−100.0% | Sold out |
| D. E. Shaw & Co., Inc. | 0 | $0 | 0.00% | −183,029−100.0% | Sold out |
| Toroso Investments, LLC | 0 | $0 | 0.00% | −180,600−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −116,327−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −57,650−100.0% | Sold out |
| Laurion Capital Management LP | 0 | $0 | 0.00% | −30,426−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −25,440−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −23,316−100.0% | Sold out |
| LMR Partners LLP | 0 | $0 | 0.00% | −16,374−100.0% | Sold out |
| Chiron Investment Management, LLC | 0 | $0 | 0.00% | −15,932−100.0% | Sold out |
| Polymer Capital Management (HK) LTD | 0 | $0 | 0.00% | −11,926−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −10,649−100.0% | Sold out |
| Symmetry Peak Management LLC | 0 | $0 | 0.00% | −800−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −247−100.0% | Sold out |
| Fairman Group, LLC | 0 | $0 | 0.00% | −85−100.0% | Sold out |
| Toronto Dominion Bank | 0 | $0 | 0.00% | −55−100.0% | Sold out |
| Pacifica Partners Inc. | 0 | $0 | 0.00% | −20−100.0% | Sold out |
| Vima LLC | 0 | $0 | 0.00% | −29−100.0% | Sold out |
| Steward Partners Investment Advisory, LLC | 0 | $0 | 0.00% | −6−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −3,779−100.0% | Sold out |
| Sofos Investments, Inc. | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| SageView Advisory Group, LLC | 0 | $0 | 0.00% | −2,648−100.0% | Sold out |
| Cutler Group LP | – | – | – | – | Not filed |