Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2024
Institutional positions in Definium Therapeutics, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 135
- +33 vs. Q4 2023
- Shares held
- 34.8M
- +29.9M (+612.9%) vs. Q4 2023
- Total value
- $327.2M
- +$309.4M (+1,731.0%) vs. Q4 2023
- New holders
- 46
- 31 more added
- Sold out
- 13
- 17 more reduced
2 institutions that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Morgan Stanley | 110,962 | $1.04M | 0.00% | +88,101+385.4% | Added |
| Citigroup Inc | 111,066 | $1.04M | 0.00% | −308−0.3% | Reduced |
| Man Group plc | 112,177 | $1.05M | 0.00% | +112,177 | New |
| Qube Research & Technologies Ltd | 116,327 | $1.09M | 0.00% | +22,678+24.2% | Added |
| State Street Corp | 118,904 | $1.12M | 0.00% | −3,200−2.6% | Reduced |
| Moloney Securities Asset Management, LLC | 161,961 | $1.52M | 0.23% | +92,450+133.0% | Added |
| Toroso Investments, LLC | 180,600 | $1.70M | 0.03% | +180,600 | New |
| D. E. Shaw & Co., Inc. | 183,029 | $1.72M | 0.00% | +183,029 | New |
| Charles Schwab Investment Management Inc | 197,214 | $1.85M | 0.00% | +5,340+2.8% | Added |
| HRT Financial LP | 207,253 | $1.95M | 0.01% | +207,253 | New |
| Susquehanna International Group, LLP | 269,596 | $2.53M | 0.00% | +39,545+17.2% | Added |
| Ikarian Capital, LLC | 297,481 | $2.80M | 0.76% | −302,519−50.4% | Reduced |
| Tang Capital Management LLC | 300,000 | $2.82M | 0.29% | +300,000 | New |
| Jane Street Group, LLC | 372,459 | $3.50M | 0.00% | +262,796+239.6% | Added |
| Tri Locum Partners LP | 379,596 | $3.57M | 1.24% | +379,596 | New |
| Millennium Management LLC | 388,202 | $3.65M | 0.00% | +280,363+260.0% | Added |
| Geode Capital Management, LLC | 389,404 | $3.66M | 0.00% | +11,489+3.0% | Added |
| Goldman Sachs Group Inc | 408,000 | $3.84M | 0.00% | +296,069+264.5% | Added |
| Vanguard Group Inc | 562,921 | $5.29M | 0.00% | −4,964−0.9% | Reduced |
| Two Sigma Investments, LP | 712,238 | $6.70M | 0.02% | +573,142+412.0% | Added |
| Soleus Capital Management, L.P. | 750,237 | $7.05M | 0.62% | +750,237 | New |
| BlackRock Inc. | 794,312 | $7.47M | 0.00% | +243,695+44.3% | Added |
| AWM Investment Company, Inc. | 833,000 | $7.83M | 1.03% | +833,000 | New |
| Janus Henderson Group PLC | 955,678 | $8.96M | 0.00% | +955,678 | New |
| Woodline Partners LP | 1,000,579 | $9.41M | 0.09% | +1,000,579 | New |
| Ally Bridge Group (NY) LLC | 1,001,452 | $9.41M | 5.23% | +1,001,452 | New |
| Blackstone Group Inc. | 1,249,875 | $11.7M | 0.05% | +1,249,875 | New |
| Marshall Wace, LLP | 1,998,544 | $18.8M | 0.03% | +1,998,544 | New |
| Great Point Partners LLC | 2,000,000 | $18.8M | 2.93% | +2,000,000 | New |
| Octagon Capital Advisors LP | 2,153,000 | $20.2M | 2.46% | +2,153,000 | New |
| Driehaus Capital Management LLC | 2,547,545 | $23.9M | 0.24% | +2,547,545 | New |
| Commodore Capital LP | 5,833,333 | $54.8M | 3.67% | +5,833,333 | New |
| Deep Track Capital, LP | 6,666,667 | $62.7M | 1.80% | +6,666,667 | New |
| PrairieView Partners, LLC | 4 | – | – | 00.0% | Unchanged |
| SageView Advisory Group, LLC | 2,648 | – | – | +2,648 | New |
| Princeton Global Asset Management LLC | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| Busey Wealth Management | 0 | $0 | 0.00% | −156,320−100.0% | Sold out |
| Cresset Asset Management, LLC | 0 | $0 | 0.00% | −154,498−100.0% | Sold out |
| Cornercap Investment Counsel Inc | 0 | $0 | 0.00% | −56,957−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −36,826−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −23,935−100.0% | Sold out |
| Regal Investment Advisors LLC | 0 | $0 | 0.00% | −14,556−100.0% | Sold out |
| Edmond de Rothschild Holding S.A. | 0 | $0 | 0.00% | −666−100.0% | Sold out |
| Householder Group Estate & Retirement Specialist, LLC | 0 | $0 | 0.00% | −600−100.0% | Sold out |
| US Bancorp | 0 | $0 | 0.00% | −66−100.0% | Sold out |
| Focused Wealth Management, Inc | 0 | $0 | 0.00% | −10−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −9−100.0% | Sold out |
| AdvisorNet Financial, Inc | 0 | $0 | 0.00% | −3−100.0% | Sold out |
| Strategic Investment Solutions, Inc. | – | – | – | – | Not filed |
| Coppell Advisory Solutions LLC | – | – | – | – | Not filed |