Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 171
- −8 vs. Q4 2025
- Shares held
- 114.1M
- +7.64M (+7.2%) vs. Q4 2025
- Total value
- $1.59B
- +$299.6M (+23.3%) vs. Q4 2025
- New holders
- 28
- 63 more added
- Sold out
- 36
- 53 more reduced
1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Parsons Capital Management Inc | 21,645 | $300.9K | 0.01% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 21,140 | $293.8K | 0.00% | −4,061−16.1% | Reduced |
| Virtus Investment Advisers, Inc. | 20,815 | $289.3K | 0.08% | +508+2.5% | Added |
| Premier Path Wealth Partners, LLC | 20,265 | $281.7K | 0.04% | 00.0% | Unchanged |
| Brown Advisory Inc | 19,930 | $277.0K | 0.00% | 00.0% | Unchanged |
| Headlands Technologies LLC | 19,814 | $275.4K | 0.03% | −10,729−35.1% | Reduced |
| China Universal Asset Management Co., Ltd. | 19,488 | $270.9K | 0.02% | +1,593+8.9% | Added |
| ProShare Advisors LLC | 18,154 | $252.3K | 0.00% | −2,914−13.8% | Reduced |
| Arizona State Retirement System | 18,099 | $251.6K | 0.00% | −4,815−21.0% | Reduced |
| Creative Planning | 17,883 | $248.6K | 0.00% | +17,883 | New |
| Vanguard Investments Australia, Ltd. | 17,713 | $246.2K | 0.00% | +17,713 | New |
| KLP Kapitalforvaltning AS | 17,400 | $241.9K | 0.00% | 00.0% | Unchanged |
| Profund Advisors LLC | 17,152 | $238.4K | 0.01% | −3,437−16.7% | Reduced |
| Seven Fleet Capital Management LP | 16,671 | $231.7K | 0.07% | +5,100+44.1% | Added |
| Voya Investment Management LLC | 15,227 | $211.7K | 0.00% | −20−0.1% | Reduced |
| Prudential Financial Inc | 14,120 | $196.3K | 0.00% | +14,120 | New |
| Verition Fund Management LLC | 13,264 | $184.4K | 0.00% | −16,223−55.0% | Reduced |
| Amundi | 12,895 | $179.2K | 0.00% | +12,895 | New |
| Royal Bank of Canada | 12,383 | $172.0K | 0.00% | −3,260−20.8% | Reduced |
| Landscape Capital Management, L.L.C. | 12,226 | $169.9K | 0.01% | 00.0% | Unchanged |
| HSBC Holdings PLC | 11,414 | $156.9K | 0.00% | +11,414 | New |
| PSP Research LLC | 10,838 | $150.6K | 0.11% | −33,385−75.5% | Reduced |
| Pictet Asset Management Holding SA | 10,768 | $149.7K | 0.00% | +10,768 | New |
| Victory Capital Management Inc | 10,644 | $148.0K | 0.00% | +92+0.9% | Added |
| Great Lakes Advisors, LLC | 10,380 | $144.3K | 0.00% | +10,380 | New |
| Valeo Financial Advisors, LLC | 10,000 | $139.0K | 0.00% | −5,000−33.3% | Reduced |
| MAI Capital Management | 9,014 | $125.3K | 0.00% | +9,014 | New |
| ACT Capital Management, LLC | 9,000 | $125.1K | 0.10% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 7,913 | $110.0K | 0.00% | −182−2.2% | Reduced |
| Ameritas Investment Partners, Inc. | 7,203 | $100.1K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 5,728 | $79.6K | 0.00% | +391+7.3% | Added |
| STRS Ohio | 3,400 | $47.3K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 2,455 | $34.1K | 0.00% | +297+13.8% | Added |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 1,803 | $29.5K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 2,063 | $28.7K | 0.00% | +63+3.2% | Added |
| State of Wyoming | 1,883 | $26.2K | 0.00% | +502+36.4% | Added |
| KBC Group NV | 1,863 | $26.0K | 0.00% | +1,863 | New |
| SRS Capital Advisors, Inc. | 1,494 | $20.8K | 0.00% | −1,056−41.4% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,418 | $19.7K | 0.00% | +103+7.8% | Added |
| Rockefeller Capital Management L.P. | 1,274 | $17.7K | 0.00% | +1,013+388.1% | Added |
| CWM, LLC | 1,263 | $17.6K | 0.00% | +70+5.9% | Added |
| Sterling Capital Management LLC | 1,137 | $15.8K | 0.00% | −490−30.1% | Reduced |
| Steward Partners Investment Advisory, LLC | 1,000 | $13.9K | 0.00% | −500−33.3% | Reduced |
| Nisa Investment Advisors, LLC | 922 | $12.8K | 0.00% | 00.0% | Unchanged |
| Westfuller Advisors, LLC | 819 | $11.4K | 0.00% | 00.0% | Unchanged |
| Fifth Third Bancorp | 755 | $10.5K | 0.00% | +755 | New |
| Meeder Asset Management Inc | 661 | $9.19K | 0.00% | −1,438−68.5% | Reduced |
| Dunhill Financial, LLC | 600 | $8.34K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 528 | $7.34K | 0.00% | +279+112.0% | Added |
| GAMMA Investing LLC | 417 | $5.80K | 0.00% | +150+56.2% | Added |
| J.Safra Asset Management Corp | 377 | $5.24K | 0.00% | +254+206.5% | Added |
| Los Angeles Capital Management LLC | 325 | $4.52K | 0.00% | −527−61.9% | Reduced |
| The PNC Financial Services Group, Inc. | 283 | $3.93K | 0.00% | −155−35.4% | Reduced |
| Massmutual Trust Co FSB | 282 | $3.92K | 0.00% | +129+84.3% | Added |
| UMA Financial Services, Inc. | 274 | $3.81K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 270 | $3.66K | 0.00% | +240+800.0% | Added |
| Signaturefd, LLC | 254 | $3.53K | 0.00% | +254 | New |
| Larson Financial Group LLC | 201 | $2.79K | 0.00% | +160+390.2% | Added |
| Eastern Bank | 200 | $2.78K | 0.00% | +200 | New |
| Harbour Investments, Inc. | 90 | $1.25K | 0.00% | 00.0% | Unchanged |
| Stone House Investment Management, LLC | 73 | $1.01K | 0.00% | +73 | New |
| Rothschild Investment LLC | 55 | $765 | 0.00% | +55 | New |
| Salem Investment Counselors Inc | 55 | $765 | 0.00% | +55 | New |
| Allworth Financial LP | 40 | $556 | 0.00% | +28+233.3% | Added |
| Caitong International Asset Management Co., Ltd | 36 | $500 | 0.00% | −3,823−99.1% | Reduced |
| EverSource Wealth Advisors, LLC | 26 | $361 | 0.00% | +1+4.0% | Added |
| Farther Finance Advisors, LLC | 22 | $316 | 0.00% | +2+10.0% | Added |
| Essential Partners LLC | 15 | $209 | 0.00% | −2−11.8% | Reduced |
| Ameritas Advisory Services, LLC | 3 | $42 | 0.00% | +3 | New |
| SBI Securities Co., Ltd. | 1 | $14 | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 9 | $0 | 0.00% | +9 | New |
| Sofinnova Investments, Inc. | 0 | $0 | 0.00% | −527,099−100.0% | Sold out |
| Silverarc Capital Management, LLC | 0 | $0 | 0.00% | −506,242−100.0% | Sold out |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −502,366−100.0% | Sold out |
| Patient Square Capital LP | 0 | $0 | 0.00% | −350,000−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −328,401−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −263,235−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −254,328−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −192,500−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −189,673−100.0% | Sold out |
| Voloridge Investment Management, LLC | 0 | $0 | 0.00% | −153,363−100.0% | Sold out |
| Atom Investors LP | 0 | $0 | 0.00% | −139,422−100.0% | Sold out |
| Bank of Montreal | 0 | $0 | 0.00% | −138,525−100.0% | Sold out |
| Kennondale Capital Management LLC | 0 | $0 | 0.00% | −53,423−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −48,112−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −46,455−100.0% | Sold out |
| Mariner, LLC | 0 | $0 | 0.00% | −46,342−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −36,758−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −35,409−100.0% | Sold out |
| Persistent Asset Partners Ltd | 0 | $0 | 0.00% | −31,147−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −24,352−100.0% | Sold out |
| SG Americas Securities, LLC | 0 | $0 | 0.00% | −20,846−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −18,358−100.0% | Sold out |
| Rafferty Asset Management, LLC | 0 | $0 | 0.00% | −17,673−100.0% | Sold out |
| Quadrature Capital Ltd | 0 | $0 | 0.00% | −15,465−100.0% | Sold out |
| Teacher Retirement System of Texas | 0 | $0 | 0.00% | −12,174−100.0% | Sold out |
| EntryPoint Capital, LLC | 0 | $0 | 0.00% | −10,487−100.0% | Sold out |
| Quest Partners LLC | 0 | $0 | 0.00% | −7,195−100.0% | Sold out |
| T. Rowe Price Investment Management, Inc. | 0 | $0 | 0.00% | −4,517−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −3,727−100.0% | Sold out |