Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 171
- −8 vs. Q4 2025
- Shares held
- 114.1M
- +7.64M (+7.2%) vs. Q4 2025
- Total value
- $1.59B
- +$299.6M (+23.3%) vs. Q4 2025
- New holders
- 28
- 63 more added
- Sold out
- 36
- 53 more reduced
1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 9 | $0 | 0.00% | +9 | New |
| SBI Securities Co., Ltd. | 1 | $14 | 0.00% | 00.0% | Unchanged |
| Ameritas Advisory Services, LLC | 3 | $42 | 0.00% | +3 | New |
| Essential Partners LLC | 15 | $209 | 0.00% | −2−11.8% | Reduced |
| Farther Finance Advisors, LLC | 22 | $316 | 0.00% | +2+10.0% | Added |
| EverSource Wealth Advisors, LLC | 26 | $361 | 0.00% | +1+4.0% | Added |
| Caitong International Asset Management Co., Ltd | 36 | $500 | 0.00% | −3,823−99.1% | Reduced |
| Allworth Financial LP | 40 | $556 | 0.00% | +28+233.3% | Added |
| Rothschild Investment LLC | 55 | $765 | 0.00% | +55 | New |
| Salem Investment Counselors Inc | 55 | $765 | 0.00% | +55 | New |
| Stone House Investment Management, LLC | 73 | $1.01K | 0.00% | +73 | New |
| Harbour Investments, Inc. | 90 | $1.25K | 0.00% | 00.0% | Unchanged |
| Eastern Bank | 200 | $2.78K | 0.00% | +200 | New |
| Larson Financial Group LLC | 201 | $2.79K | 0.00% | +160+390.2% | Added |
| Signaturefd, LLC | 254 | $3.53K | 0.00% | +254 | New |
| Jones Financial Companies LLLP | 270 | $3.66K | 0.00% | +240+800.0% | Added |
| UMA Financial Services, Inc. | 274 | $3.81K | 0.00% | 00.0% | Unchanged |
| Massmutual Trust Co FSB | 282 | $3.92K | 0.00% | +129+84.3% | Added |
| The PNC Financial Services Group, Inc. | 283 | $3.93K | 0.00% | −155−35.4% | Reduced |
| Los Angeles Capital Management LLC | 325 | $4.52K | 0.00% | −527−61.9% | Reduced |
| J.Safra Asset Management Corp | 377 | $5.24K | 0.00% | +254+206.5% | Added |
| GAMMA Investing LLC | 417 | $5.80K | 0.00% | +150+56.2% | Added |
| Advisor Group Holdings, Inc. | 528 | $7.34K | 0.00% | +279+112.0% | Added |
| Dunhill Financial, LLC | 600 | $8.34K | 0.00% | 00.0% | Unchanged |
| Meeder Asset Management Inc | 661 | $9.19K | 0.00% | −1,438−68.5% | Reduced |
| Fifth Third Bancorp | 755 | $10.5K | 0.00% | +755 | New |
| Westfuller Advisors, LLC | 819 | $11.4K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 922 | $12.8K | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 1,000 | $13.9K | 0.00% | −500−33.3% | Reduced |
| Sterling Capital Management LLC | 1,137 | $15.8K | 0.00% | −490−30.1% | Reduced |
| CWM, LLC | 1,263 | $17.6K | 0.00% | +70+5.9% | Added |
| Rockefeller Capital Management L.P. | 1,274 | $17.7K | 0.00% | +1,013+388.1% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,418 | $19.7K | 0.00% | +103+7.8% | Added |
| SRS Capital Advisors, Inc. | 1,494 | $20.8K | 0.00% | −1,056−41.4% | Reduced |
| KBC Group NV | 1,863 | $26.0K | 0.00% | +1,863 | New |
| State of Wyoming | 1,883 | $26.2K | 0.00% | +502+36.4% | Added |
| US Bancorp | 2,063 | $28.7K | 0.00% | +63+3.2% | Added |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 1,803 | $29.5K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 2,455 | $34.1K | 0.00% | +297+13.8% | Added |
| STRS Ohio | 3,400 | $47.3K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 5,728 | $79.6K | 0.00% | +391+7.3% | Added |
| Ameritas Investment Partners, Inc. | 7,203 | $100.1K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 7,913 | $110.0K | 0.00% | −182−2.2% | Reduced |
| ACT Capital Management, LLC | 9,000 | $125.1K | 0.10% | 00.0% | Unchanged |
| MAI Capital Management | 9,014 | $125.3K | 0.00% | +9,014 | New |
| Valeo Financial Advisors, LLC | 10,000 | $139.0K | 0.00% | −5,000−33.3% | Reduced |
| Great Lakes Advisors, LLC | 10,380 | $144.3K | 0.00% | +10,380 | New |
| Victory Capital Management Inc | 10,644 | $148.0K | 0.00% | +92+0.9% | Added |
| Pictet Asset Management Holding SA | 10,768 | $149.7K | 0.00% | +10,768 | New |
| PSP Research LLC | 10,838 | $150.6K | 0.11% | −33,385−75.5% | Reduced |
| HSBC Holdings PLC | 11,414 | $156.9K | 0.00% | +11,414 | New |
| Landscape Capital Management, L.L.C. | 12,226 | $169.9K | 0.01% | 00.0% | Unchanged |
| Royal Bank of Canada | 12,383 | $172.0K | 0.00% | −3,260−20.8% | Reduced |
| Amundi | 12,895 | $179.2K | 0.00% | +12,895 | New |
| Verition Fund Management LLC | 13,264 | $184.4K | 0.00% | −16,223−55.0% | Reduced |
| Prudential Financial Inc | 14,120 | $196.3K | 0.00% | +14,120 | New |
| Voya Investment Management LLC | 15,227 | $211.7K | 0.00% | −20−0.1% | Reduced |
| Seven Fleet Capital Management LP | 16,671 | $231.7K | 0.07% | +5,100+44.1% | Added |
| Profund Advisors LLC | 17,152 | $238.4K | 0.01% | −3,437−16.7% | Reduced |
| KLP Kapitalforvaltning AS | 17,400 | $241.9K | 0.00% | 00.0% | Unchanged |
| Vanguard Investments Australia, Ltd. | 17,713 | $246.2K | 0.00% | +17,713 | New |
| Creative Planning | 17,883 | $248.6K | 0.00% | +17,883 | New |
| Arizona State Retirement System | 18,099 | $251.6K | 0.00% | −4,815−21.0% | Reduced |
| ProShare Advisors LLC | 18,154 | $252.3K | 0.00% | −2,914−13.8% | Reduced |
| China Universal Asset Management Co., Ltd. | 19,488 | $270.9K | 0.02% | +1,593+8.9% | Added |
| Headlands Technologies LLC | 19,814 | $275.4K | 0.03% | −10,729−35.1% | Reduced |
| Brown Advisory Inc | 19,930 | $277.0K | 0.00% | 00.0% | Unchanged |
| Premier Path Wealth Partners, LLC | 20,265 | $281.7K | 0.04% | 00.0% | Unchanged |
| Virtus Investment Advisers, Inc. | 20,815 | $289.3K | 0.08% | +508+2.5% | Added |
| BNP Paribas Arbitrage, SA | 21,140 | $293.8K | 0.00% | −4,061−16.1% | Reduced |
| Parsons Capital Management Inc | 21,645 | $300.9K | 0.01% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 21,900 | $304.4K | 0.00% | 00.0% | Unchanged |
| State of New Jersey Common Pension Fund D | 22,519 | $313.0K | 0.00% | +22,519 | New |
| Police & Firemen's Retirement System of New Jersey | 23,752 | $330.2K | 0.00% | 00.0% | Unchanged |
| JustInvest LLC | 24,072 | $334.6K | 0.00% | +3,232+15.5% | Added |
| Intech Investment Management LLC | 24,921 | $346.4K | 0.00% | −7,085−22.1% | Reduced |
| Guggenheim Capital LLC | 25,513 | $354.6K | 0.00% | +270+1.1% | Added |
| Integrated Quantitative Investments LLC | 27,234 | $378.6K | 0.07% | 00.0% | Unchanged |
| AQR Capital Management LLC | 29,089 | $404.3K | 0.00% | +1,242+4.5% | Added |
| Tudor Investment Corp Et Al | 31,334 | $435.5K | 0.00% | +8,932+39.9% | Added |
| Citigroup Inc | 31,782 | $441.8K | 0.00% | −6,250−16.4% | Reduced |
| Optimize Financial Inc | 32,001 | $444.8K | 0.22% | +32,001 | New |
| Manufacturers Life Insurance Company, The | 38,781 | $539.1K | 0.00% | +11,793+43.7% | Added |
| Susquehanna International Group, LLP | 39,802 | $553.2K | 0.00% | −29,090−42.2% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 40,790 | $567.0K | 0.00% | +4,913+13.7% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 42,553 | $591.5K | 0.00% | +1,387+3.4% | Added |
| Vanguard Asset Management, Ltd | 43,283 | $601.6K | 0.00% | +43,283 | New |
| Vanguard Global Advisers, LLC | 47,851 | $665.1K | 0.00% | +47,851 | New |
| Numerai GP LLC | 48,553 | $674.9K | 0.07% | −64,095−56.9% | Reduced |
| Maven Securities LTD | 50,000 | $695.0K | 0.04% | +50,000 | New |
| MetLife Investment Management | 51,587 | $717.1K | 0.00% | +1,933+3.9% | Added |
| EAM Investors, LLC | 53,256 | $740.3K | 0.09% | 00.0% | Unchanged |
| Campbell & CO Investment Adviser LLC | 54,422 | $756.5K | 0.04% | −24,341−30.9% | Reduced |
| Legal & General Group Plc | 55,773 | $775.2K | 0.00% | −16,839−23.2% | Reduced |
| Russell Investments Group, Ltd. | 59,346 | $824.9K | 0.00% | −6,092−9.3% | Reduced |
| Walleye Capital LLC | 61,711 | $857.8K | 0.01% | +55,971+975.1% | Added |
| California State Teachers Retirement System | 65,002 | $903.5K | 0.00% | −14,088−17.8% | Reduced |
| Alliancebernstein L.P. | 80,800 | $976.1K | 0.00% | +9,300+13.0% | Added |
| State of Wisconsin Investment Board | 72,061 | $1.00M | 0.00% | −12,083−14.4% | Reduced |
| D. E. Shaw & Co., Inc. | 74,230 | $1.03M | 0.00% | +1,006+1.4% | Added |