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Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

Q1 2026 vs. Q4 2025

How the institutions holding Amylyx Pharmaceuticals, Inc. changed between Q4 2025 and Q1 2026.

All holders in Q1 2026All holders in Q4 2025

13F holders of AMLX: Q4 2025 compared with Q1 2026
MeasureQ4 2025Of which not filed for Q1 2026Q1 2026Change
Holders1801171−8
Shares112.3M5.80M114.1M+7.64M (+7.2%)
Value$1.36B$70.1M$1.59B+$299.6M (+23.3%)

1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so the changes leave them out.

New holders (28)

Institutions that held Amylyx Pharmaceuticals, Inc. at the end of Q1 2026 but not at the end of Q4 2025.

Institutions new to AMLX in Q1 2026
InstitutionSharesValue% of portfolio
Vanguard Capital Management LLC4,141,575$57.6M0.00%
Jones Hill Capital LP1,598,794$22.2M4.76%
Siren, L.L.C.1,230,000$17.1M0.47%
Vanguard Portfolio Management LLC944,781$13.1M0.00%
Vanguard Fiduciary Trust Co586,152$8.15M0.00%
iA Global Asset Management Inc.304,786$4.24M0.06%
Maven Securities LTD50,000$695.0K0.04%
Vanguard Global Advisers, LLC47,851$665.1K0.00%
Vanguard Asset Management, Ltd43,283$601.6K0.00%
Optimize Financial Inc32,001$444.8K0.22%
State of New Jersey Common Pension Fund D22,519$313.0K0.00%
Creative Planning17,883$248.6K0.00%
Vanguard Investments Australia, Ltd.17,713$246.2K0.00%
Prudential Financial Inc14,120$196.3K0.00%
Amundi12,895$179.2K0.00%
HSBC Holdings PLC11,414$156.9K0.00%
Pictet Asset Management Holding SA10,768$149.7K0.00%
Great Lakes Advisors, LLC10,380$144.3K0.00%
MAI Capital Management9,014$125.3K0.00%
KBC Group NV1,863$26.0K0.00%
Fifth Third Bancorp755$10.5K0.00%
Signaturefd, LLC254$3.53K0.00%
Eastern Bank200$2.78K0.00%
Stone House Investment Management, LLC73$1.01K0.00%
Rothschild Investment LLC55$7650.00%
Salem Investment Counselors Inc55$7650.00%
Ameritas Advisory Services, LLC3$420.00%
Covestor Ltd9$00.00%

Sold out (36)

Institutions that held Amylyx Pharmaceuticals, Inc. at the end of Q4 2025 and filed for Q1 2026 without it.

Not filed for Q1 2026 yet (1)

Institutions that held Amylyx Pharmaceuticals, Inc. at the end of Q4 2025 and haven't filed a 13F for Q1 2026. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding AMLX in Q4 2025 that haven't filed for Q1 2026
InstitutionShares, Q4 2025Value, Q4 2025
Vanguard Group Inc5,804,912$70.1M