Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 131
- −5 vs. Q1 2025
- Shares held
- 81.7M
- +7.79M (+10.5%) vs. Q1 2025
- Total value
- $523.6M
- +$262.0M (+100.2%) vs. Q1 2025
- New holders
- 31
- 37 more added
- Sold out
- 36
- 37 more reduced
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| SBI Securities Co., Ltd. | 1 | $6 | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 25 | $160 | 0.00% | 00.0% | Unchanged |
| Skopos Labs, Inc. | 42 | $270 | 0.00% | +42 | New |
| The PNC Financial Services Group, Inc. | 53 | $340 | 0.00% | 00.0% | Unchanged |
| Salem Investment Counselors Inc | 55 | $353 | 0.00% | 00.0% | Unchanged |
| Catherine Avery Investment Management LLC | 87 | $558 | 0.00% | 00.0% | Unchanged |
| Harbour Investments, Inc. | 90 | $577 | 0.00% | 00.0% | Unchanged |
| Raymond James Financial Inc | 104 | $667 | 0.00% | +104 | New |
| Advisor Group Holdings, Inc. | 240 | $1.54K | 0.00% | +240 | New |
| UMA Financial Services, Inc. | 274 | $1.76K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 285 | $1.83K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 266 | $2.00K | 0.00% | 00.0% | Unchanged |
| North Capital, Inc. | 500 | $3.21K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 552 | $3.54K | 0.00% | +552 | New |
| Dunhill Financial, LLC | 600 | $3.85K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 890 | $6.00K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,700 | $10.9K | 0.00% | 00.0% | Unchanged |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 1,803 | $11.6K | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 2,000 | $12.8K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 2,369 | $15.0K | 0.00% | +2,369 | New |
| Global Retirement Partners, LLC | 2,500 | $16.0K | 0.00% | +2,500 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 2,823 | $18.1K | 0.00% | −329−10.4% | Reduced |
| Caitong International Asset Management Co., Ltd | 2,913 | $18.7K | 0.01% | +684+30.7% | Added |
| Mirae Asset Global Investments Co., Ltd. | 3,443 | $22.1K | 0.00% | +513+17.5% | Added |
| US Bancorp | 4,000 | $25.6K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 4,328 | $27.7K | 0.00% | +4,328 | New |
| Russell Investments Group, Ltd. | 6,229 | $39.9K | 0.00% | −471−7.0% | Reduced |
| Ameritas Investment Partners, Inc. | 7,081 | $45.4K | 0.00% | +7,081 | New |
| BNP Paribas Arbitrage, SA | 7,267 | $46.6K | 0.00% | +5,904+433.2% | Added |
| STRS Ohio | 7,300 | $46.8K | 0.00% | +7,300 | New |
| Legal & General Group Plc | 7,402 | $47.4K | 0.00% | +7,402 | New |
| Tower Research Capital LLC (TRC) | 7,467 | $47.9K | 0.00% | +664+9.8% | Added |
| Valeo Financial Advisors, LLC | 10,000 | $64.1K | 0.00% | 00.0% | Unchanged |
| Tudor Investment Corp Et Al | 12,073 | $77.4K | 0.00% | −21,355−63.9% | Reduced |
| Royal Bank of Canada | 12,133 | $78.0K | 0.00% | +283+2.4% | Added |
| Prudential Financial Inc | 15,620 | $100.1K | 0.00% | +420+2.8% | Added |
| Police & Firemen's Retirement System of New Jersey | 15,992 | $102.5K | 0.00% | +15,992 | New |
| ProShare Advisors LLC | 17,551 | $112.5K | 0.00% | +17,551 | New |
| China Universal Asset Management Co., Ltd. | 17,904 | $114.8K | 0.01% | +716+4.2% | Added |
| Voya Investment Management LLC | 19,476 | $124.8K | 0.00% | +19,476 | New |
| Brown Advisory Inc | 19,930 | $127.8K | 0.00% | 00.0% | Unchanged |
| Marex Group plc | 20,000 | $128.2K | 0.00% | 00.0% | Unchanged |
| Premier Path Wealth Partners, LLC | 20,265 | $129.9K | 0.02% | 00.0% | Unchanged |
| JustInvest LLC | 21,123 | $135.4K | 0.00% | −633−2.9% | Reduced |
| Parsons Capital Management Inc | 21,645 | $138.7K | 0.01% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 21,900 | $140.4K | 0.00% | +21,900 | New |
| Los Angeles Capital Management LLC | 23,320 | $149.5K | 0.00% | +23,320 | New |
| Bridgeway Capital Management, LLC | 25,700 | $164.7K | 0.00% | −130,000−83.5% | Reduced |
| Group One Trading, L.P. | 25,856 | $165.7K | 0.01% | −17,378−40.2% | Reduced |
| Manufacturers Life Insurance Company, The | 25,999 | $166.7K | 0.00% | +25,999 | New |
| Quadrature Capital Ltd | 29,430 | $188.4K | 0.00% | +16,686+130.9% | Added |
| Alliancebernstein L.P. | 30,600 | $196.1K | 0.00% | +30,600 | New |
| Citigroup Inc | 31,098 | $199.3K | 0.00% | −432,142−93.3% | Reduced |
| Graham Capital Management, L.P. | 34,153 | $218.9K | 0.01% | +34,153 | New |
| Guggenheim Capital LLC | 35,752 | $229.2K | 0.00% | −2,044−5.4% | Reduced |
| Intech Investment Management LLC | 36,315 | $232.8K | 0.00% | +36,315 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 37,987 | $243.5K | 0.00% | +37,987 | New |
| Wells Fargo & Company | 38,101 | $244.2K | 0.00% | +37,801+12,600.3% | Added |
| Squarepoint Ops LLC | 40,643 | $260.5K | 0.00% | −35,206−46.4% | Reduced |
| MetLife Investment Management | 42,929 | $275.2K | 0.00% | +42,929 | New |
| Centiva Capital, LP | 45,464 | $291.4K | 0.02% | +17,242+61.1% | Added |
| Jump Financial, LLC | 47,800 | $306.4K | 0.00% | +47,800 | New |
| Mariner, LLC | 48,668 | $312.0K | 0.00% | −2,238−4.4% | Reduced |
| Cantor Fitzgerald, L. P. | 50,000 | $320.5K | 0.01% | −50,000−50.0% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 56,831 | $364.3K | 0.01% | −26,405−31.7% | Reduced |
| JPMorgan Chase & Co | 87,989 | $564.0K | 0.00% | +33,920+62.7% | Added |
| Price T Rowe Associates Inc | 91,392 | $586.0K | 0.00% | +33,692+58.4% | Added |
| Kennondale Capital Management LLC | 95,165 | $610.0K | 0.62% | −107,578−53.1% | Reduced |
| Ameriprise Financial Inc | 95,219 | $610.4K | 0.00% | +82,414+643.6% | Added |
| EAM Investors, LLC | 99,960 | $640.7K | 0.10% | +99,960 | New |
| Tang Capital Management LLC | 100,000 | $641.0K | 0.03% | 00.0% | Unchanged |
| Rhumbline Advisers | 100,576 | $644.7K | 0.00% | +100,576 | New |
| Susquehanna International Group, LLP | 110,846 | $710.5K | 0.00% | −1,360,079−92.5% | Reduced |
| Allostery Investments LP | 120,119 | $770.0K | 9.81% | −145,980−54.9% | Reduced |
| Cubist Systematic Strategies, LLC | 123,242 | $790.0K | 0.01% | +40,112+48.3% | Added |
| Barclays PLC | 130,274 | $835.1K | 0.00% | −7,131−5.2% | Reduced |
| American Century Companies Inc | 134,380 | $861.4K | 0.00% | +27,366+25.6% | Added |
| Bank of Montreal | 143,512 | $919.9K | 0.00% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 150,837 | $966.9K | 0.00% | +150,837 | New |
| D. E. Shaw & Co., Inc. | 151,502 | $971.1K | 0.00% | −118,504−43.9% | Reduced |
| Nuveen, LLC | 155,536 | $997.0K | 0.00% | +155,536 | New |
| Gsa Capital Partners LLP | 170,533 | $1.09M | 0.08% | +147,448+638.7% | Added |
| Jane Street Group, LLC | 186,986 | $1.20M | 0.00% | −144,199−43.5% | Reduced |
| Federated Hermes, Inc. | 203,930 | $1.31M | 0.00% | +1,145+0.6% | Added |
| Aldebaran Capital, LLC | 217,827 | $1.40M | 1.38% | −41,426−16.0% | Reduced |
| Polygon Management Ltd. | 218,750 | $1.40M | 0.25% | +218,750 | New |
| Y-Intercept (Hong Kong) Ltd | 240,379 | $1.54M | 0.04% | +240,379 | New |
| J. Goldman & Co LP | 258,600 | $1.66M | 0.05% | +258,600 | New |
| Falcon Edge Capital, LP | 275,842 | $1.77M | 0.19% | +88,531+47.3% | Added |
| Wellington Management Group LLP | 288,618 | $1.85M | 0.00% | −2,064−0.7% | Reduced |
| OrbiMed Advisors LLC | 313,200 | $2.01M | 0.05% | −34,800−10.0% | Reduced |
| Dimensional Fund Advisors LP | 373,739 | $2.40M | 0.00% | +250,163+202.4% | Added |
| Renaissance Technologies LLC | 396,200 | $2.54M | 0.00% | −118,900−23.1% | Reduced |
| Qube Research & Technologies Ltd | 438,026 | $2.81M | 0.00% | −504,865−53.5% | Reduced |
| Bank of America Corp | 451,808 | $2.90M | 0.00% | −342,546−43.1% | Reduced |
| Two Sigma Advisers, LP | 470,000 | $3.01M | 0.01% | −179,800−27.7% | Reduced |
| Morgan Stanley | 486,893 | $3.12M | 0.00% | +12,475+2.6% | Added |
| Rock Springs Capital Management LP | 499,764 | $3.20M | 0.20% | +156,536+45.6% | Added |
| Two Sigma Investments, LP | 558,846 | $3.58M | 0.01% | −203,207−26.7% | Reduced |
| Acadian Asset Management LLC | 569,083 | $3.65M | 0.01% | +326,976+135.1% | Added |