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Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

Q2 2025 vs. Q1 2025

How the institutions holding Amylyx Pharmaceuticals, Inc. changed between Q1 2025 and Q2 2025.

All holders in Q2 2025All holders in Q1 2025

13F holders of AMLX: Q1 2025 compared with Q2 2025
MeasureQ1 2025Q2 2025Change
Holders136131−5
Shares73.9M81.7M+7.79M (+10.5%)
Value$261.6M$523.6M+$262.0M (+100.2%)

New holders (31)

Institutions that held Amylyx Pharmaceuticals, Inc. at the end of Q2 2025 but not at the end of Q1 2025.

Institutions new to AMLX in Q2 2025
InstitutionSharesValue% of portfolio
Driehaus Capital Management LLC1,264,997$8.11M0.06%
Parkman Healthcare Partners LLC650,000$4.17M0.48%
J. Goldman & Co LP258,600$1.66M0.05%
Y-Intercept (Hong Kong) Ltd240,379$1.54M0.04%
Polygon Management Ltd.218,750$1.40M0.25%
Nuveen, LLC155,536$997.0K0.00%
Bank of New York Mellon Corp150,837$966.9K0.00%
Rhumbline Advisers100,576$644.7K0.00%
EAM Investors, LLC99,960$640.7K0.10%
Jump Financial, LLC47,800$306.4K0.00%
MetLife Investment Management42,929$275.2K0.00%
Mirae Asset Global ETFs Holdings Ltd.37,987$243.5K0.00%
Intech Investment Management LLC36,315$232.8K0.00%
Graham Capital Management, L.P.34,153$218.9K0.01%
Alliancebernstein L.P.30,600$196.1K0.00%
Manufacturers Life Insurance Company, The25,999$166.7K0.00%
Los Angeles Capital Management LLC23,320$149.5K0.00%
New York State Common Retirement Fund21,900$140.4K0.00%
Voya Investment Management LLC19,476$124.8K0.00%
ProShare Advisors LLC17,551$112.5K0.00%
Police & Firemen's Retirement System of New Jersey15,992$102.5K0.00%
Legal & General Group Plc7,402$47.4K0.00%
STRS Ohio7,300$46.8K0.00%
Ameritas Investment Partners, Inc.7,081$45.4K0.00%
California State Teachers Retirement System4,328$27.7K0.00%
Global Retirement Partners, LLC2,500$16.0K0.00%
Amalgamated Bank2,369$15.0K0.00%
Sterling Capital Management LLC552$3.54K0.00%
Advisor Group Holdings, Inc.240$1.54K0.00%
Raymond James Financial Inc104$6670.00%
Skopos Labs, Inc.42$2700.00%

Sold out (36)

Institutions that held Amylyx Pharmaceuticals, Inc. at the end of Q1 2025 and filed for Q2 2025 without it.

Institutions that sold out of AMLX in Q2 2025
InstitutionShares, Q1 2025Value, Q1 2025
Alyeska Investment Group, L.P.750,412$2.66M
Walleye Capital LLC250,888$888.1K
Marshall Wace, LLP247,275$875.4K
Omers Administration Corp169,600$600.4K
Balyasny Asset Management LLC148,559$525.9K
HRT Financial LP127,998$453.0K
Man Group plc87,352$309.2K
Jacobs Levy Equity Management, Inc77,091$272.9K
Jain Global LLC73,942$261.8K
Alps Advisors Inc67,597$239.3K
ExodusPoint Capital Management, LP59,491$211.0K
Algert Global LLC57,133$202.3K
Jefferies Financial Group Inc.46,200$163.5K
LMR Partners LLP43,228$153.0K
Point72 Asia (Singapore) Pte. Ltd.43,200$152.9K
Quantessence Capital LLC40,134$142.1K
XTX Topco Ltd39,542$140.0K
Cannon Global Investment Management, LLC25,500$90.3K
SG Americas Securities, LLC25,210$89.0K
Verition Fund Management LLC24,013$85.0K
Paloma Partners Management Co22,242$78.7K
Capstone Investment Advisors, LLC16,150$57.2K
State of Wyoming15,920$56.4K
Catalyst Funds Management Pty Ltd14,905$52.8K
HSBC Holdings PLC14,419$51.4K
Engineers Gate Manager LP13,382$47.4K
Two Sigma Securities, LLC13,301$47.1K
R Squared Ltd12,736$45.1K
Brevan Howard Capital Management LP11,330$40.1K
Capula Management Ltd10,980$38.9K
EntryPoint Capital, LLC10,587$37.5K
Hudson Bay Capital Management LP10,340$36.6K
Point72 (DIFC) Ltd5,047$17.9K
Simplex Trading, LLC4,162$14.0K
Advisors Asset Management, Inc.2,573$9.11K
Coldstream Capital Management Inc238$843