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Tyra Biosciences, Inc.

TYRA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001863127

In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Tyra Biosciences, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
168
+6 vs. Q1 2026
Shares held
69.3M
+7.29M (+11.7%) vs. Q1 2026
Total value
$2.22B
−$160.6M (−6.8%) vs. Q1 2026
New holders
32
73 more added
Sold out
26
44 more reduced

2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 168 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 26 institutionsQ4 2021: 45 institutionsQ1 2022: 46 institutionsQ2 2022: 48 institutionsQ3 2022: 49 institutionsQ4 2022: 46 institutionsQ1 2023: 51 institutionsQ2 2023: 59 institutionsQ3 2023: 59 institutionsQ4 2023: 62 institutionsQ1 2024: 77 institutionsQ2 2024: 79 institutionsQ3 2024: 95 institutionsQ4 2024: 113 institutionsQ1 2025: 117 institutionsQ2 2025: 121 institutionsQ3 2025: 116 institutionsQ4 2025: 133 institutionsQ1 2026: 164 institutionsQ2 2026: 168 institutions
Value heldQ2 2026: $2.22B
Q1 2021: $0Q2 2021: $0Q3 2021: $456.8MQ4 2021: $494.2MQ1 2022: $386.6MQ2 2022: $255.6MQ3 2022: $313.8MQ4 2022: $267.8MQ1 2023: $573.0MQ2 2023: $616.7MQ3 2023: $502.1MQ4 2023: $495.2MQ1 2024: $768.4MQ2 2024: $748.6MQ3 2024: $1.11BQ4 2024: $675.8MQ1 2025: $499.5MQ2 2025: $541.5MQ3 2025: $778.4MQ4 2025: $1.49BQ1 2026: $2.52BQ2 2026: $2.22B
Institutions holding TYRA and their total value by quarter
QuarterHoldersValue
Q2 2026168$2.22B
Q1 2026164$2.52B
Q4 2025133$1.49B
Q3 2025116$778.4M
Q2 2025121$541.5M
Q1 2025117$499.5M
Q4 2024113$675.8M
Q3 202495$1.11B
Q2 202479$748.6M
Q1 202477$768.4M
Q4 202362$495.2M
Q3 202359$502.1M
Q2 202359$616.7M
Q1 202351$573.0M
Q4 202246$267.8M
Q3 202249$313.8M
Q2 202248$255.6M
Q1 202246$386.6M
Q4 202145$494.2M
Q3 202126$456.8M
Q2 20210$0
Q1 20210$0

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q1 2026.

Institutions holding TYRA in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Global Advisers, LLC20,154$643.7K0.00%+4,674+30.2%Added
Elmind Capital, LP20,000$638.8K0.16%−330,000−94.3%Reduced
Profund Advisors LLC19,588$625.6K0.02%+3,932+25.1%Added
Legal & General Group Plc18,017$575.5K0.00%+8,480+88.9%Added
UBS Asset Management Americas Inc17,688$565.0K0.00%+9,856+125.8%Added
Ameriprise Financial Inc16,920$540.4K0.00%−127,980−88.3%Reduced
Winton Group Ltd16,800$536.6K0.02%+16,800New
Vanguard Asset Management, Ltd15,479$494.4K0.00%+6,488+72.2%Added
Fox Run Management, L.L.C.14,450$461.5K0.08%+14,450New
New York State Common Retirement Fund12,923$412.8K0.00%+5,500+74.1%Added
Virtus Investment Advisers, Inc.12,123$387.2K0.09%+74+0.6%Added
Police & Firemen's Retirement System of New Jersey10,850$346.5K0.00%+4,410+68.5%Added
Baker Bros. Advisors LP10,607$338.8K0.00%00.0%Unchanged
Susquehanna Fundamental Investments, LLC10,459$334.1K0.01%+10,459New
Cinctive Capital Management LP10,184$325.3K0.01%−67,834−86.9%Reduced
Capstone Investment Advisors, LLC10,051$321.0K0.00%+10,051New
China Universal Asset Management Co., Ltd.9,465$302.3K0.02%−6−0.1%Reduced
Jain Global LLC8,605$274.8K0.00%+8,605New
Zurcher Kantonalbank (Zurich Cantonalbank)8,523$272.2K0.00%+485+6.0%Added
Savant Capital, LLC7,141$251.4K0.00%+7,141New
Public Employees Retirement System of Ohio7,422$237.1K0.00%−13,100−63.8%Reduced
Intech Investment Management LLC7,419$237.0K0.00%+1,074+16.9%Added
Vanguard Investments Australia, Ltd.7,349$234.7K0.00%+4,421+151.0%Added
State of New Jersey Common Pension Fund D7,213$230.4K0.00%+7,213New
Canada Pension Plan Investment Board7,200$230.0K0.00%−7,100−49.7%Reduced
ProShare Advisors LLC6,765$216.1K0.00%+623+10.1%Added
KLP Kapitalforvaltning AS5,100$162.9K0.00%+2,200+75.9%Added
Ameritas Investment Partners, Inc.3,339$106.6K0.00%+1,348+67.7%Added
Tower Research Capital LLC (TRC)2,930$93.6K0.00%−75−2.5%Reduced
Acadian Asset Management LLC2,906$92.0K0.00%+2,906New
Mirae Asset Global Investments Co., Ltd.2,660$85.0K0.00%−124−4.5%Reduced
State of Wyoming2,389$76.3K0.01%+2,389New
Hilton Head Capital Partners, LLC2,024$64.6K0.03%+1,252+162.2%Added
Chung Wu Investment Group, LLC2,000$63.9K0.04%00.0%Unchanged
Caitong International Asset Management Co., Ltd1,918$61.3K0.01%+27+1.4%Added
Steward Partners Investment Advisory, LLC1,227$39.2K0.00%−350−22.2%Reduced
Advisor Group Holdings, Inc.1,190$38.0K0.00%+639+116.0%Added
GF Fund Management Co. Ltd.1,131$36.1K0.00%−67−5.6%Reduced
Royal Bank of Canada1,126$36.0K0.00%+1,038+1,179.5%Added
Versant Capital Management, Inc819$26.2K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC771$24.6K0.00%+683+776.1%Added
Pacer Advisors, Inc.646$21.0K0.00%+646New
GAMMA Investing LLC505$16.1K0.00%−1−0.2%Reduced
Rockefeller Capital Management L.P.421$13.4K0.00%00.0%Unchanged
Federated Hermes, Inc.369$11.8K0.00%−345−48.3%Reduced
The PNC Financial Services Group, Inc.208$6.64K0.00%−15−6.7%Reduced
Larson Financial Group LLC150$4.79K0.00%−145−49.2%Reduced
True Wealth Design, LLC142$4.54K0.00%00.0%Unchanged
Sterling Capital Management LLC129$4.12K0.00%−729−85.0%Reduced
Smartleaf Asset Management LLC127$4.08K0.00%00.0%Unchanged
Allworth Financial LP100$3.19K0.00%−4−3.8%Reduced
Atlantic Union Bankshares Corp100$3.19K0.00%00.0%Unchanged
Optiver Holding B.V.98$3.13K0.00%−8−7.5%Reduced
SRS Capital Advisors, Inc.87$2.78K0.00%+87New
Farther Finance Advisors, LLC60$1.92K0.00%00.0%Unchanged
Rothschild Investment LLC55$1.76K0.00%−15−21.4%Reduced
EverSource Wealth Advisors, LLC44$1.41K0.00%−84−65.6%Reduced
Signaturefd, LLC43$1.37K0.00%00.0%Unchanged
Covestor Ltd16$1.00K0.00%+10+166.7%Added
Clearstead Advisors, LLC29$9210.00%00.0%Unchanged
Fortitude Family Office, LLC17$5430.00%+17New
National Bank of Canada15$4800.00%+15New
Quarry LP12$3830.00%+12New
Global Retirement Partners, LLC7$2240.00%+7New
SBI Securities Co., Ltd.2$640.00%−2−50.0%Reduced
TFC Financial Management1$320.00%00.0%Unchanged
Keating Financial Advisory Services, Inc.1$320.00%+1New
Silver Grove Financial Group, Inc.1$320.00%+1New
Farallon Capital Management, L.L.C.0$00.00%−3,580,818−100.0%Sold out
Logos Global Management LP0$00.00%−850,000−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−351,479−100.0%Sold out
Seven Fleet Capital Management LP0$00.00%−198,585−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−79,592−100.0%Sold out
Catalio Capital Management, LP0$00.00%−67,285−100.0%Sold out
Vestal Point Capital, LP0$00.00%−54,000−100.0%Sold out
American Century Companies Inc0$00.00%−47,929−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−38,850−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−38,606−100.0%Sold out
Eversept Partners, LP0$00.00%−27,055−100.0%Sold out
Quadrature Capital Ltd0$00.00%−18,203−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−16,284−100.0%Sold out
PSP Research LLC0$00.00%−16,000−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−15,543−100.0%Sold out
Jane Street Group, LLC0$00.00%−10,169−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−10,000−100.0%Sold out
Arrowpoint Investment Partners (Singapore) Pte. Ltd.0$00.00%−8,075−100.0%Sold out
Bridgefront Capital, LLC0$00.00%−7,911−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−7,000−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−5,756−100.0%Sold out
Persistent Asset Partners Ltd0$00.00%−4,518−100.0%Sold out
Quantbot Technologies LP0$00.00%−243−100.0%Sold out
US Bancorp0$00.00%−11−100.0%Sold out
Twin Peaks Wealth Advisors, LLC0$00.00%−7−100.0%Sold out
MAI Capital Management0$00.00%−4−100.0%Sold out
Janus Henderson Group PLC––––Not filed
CWM, LLC––––Not filed