Skip to main content

Tyra Biosciences, Inc.

TYRA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001863127

In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Tyra Biosciences, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
121
+4 vs. Q1 2025
Shares held
56.6M
+3.02M (+5.6%) vs. Q1 2025
Total value
$541.5M
+$42.0M (+8.4%) vs. Q1 2025
New holders
18
62 more added
Sold out
14
20 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 121 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 26 institutionsQ4 2021: 45 institutionsQ1 2022: 46 institutionsQ2 2022: 48 institutionsQ3 2022: 49 institutionsQ4 2022: 46 institutionsQ1 2023: 51 institutionsQ2 2023: 59 institutionsQ3 2023: 59 institutionsQ4 2023: 62 institutionsQ1 2024: 77 institutionsQ2 2024: 79 institutionsQ3 2024: 95 institutionsQ4 2024: 113 institutionsQ1 2025: 117 institutionsQ2 2025: 121 institutionsQ3 2025: 116 institutionsQ4 2025: 133 institutionsQ1 2026: 164 institutionsQ2 2026: 168 institutions
Value heldQ2 2025: $541.5M
Q1 2021: $0Q2 2021: $0Q3 2021: $456.8MQ4 2021: $494.2MQ1 2022: $386.6MQ2 2022: $255.6MQ3 2022: $313.8MQ4 2022: $267.8MQ1 2023: $573.0MQ2 2023: $616.7MQ3 2023: $502.1MQ4 2023: $495.2MQ1 2024: $768.4MQ2 2024: $748.6MQ3 2024: $1.11BQ4 2024: $675.8MQ1 2025: $499.5MQ2 2025: $541.5MQ3 2025: $778.4MQ4 2025: $1.49BQ1 2026: $2.52BQ2 2026: $2.22B
Institutions holding TYRA and their total value by quarter
QuarterHoldersValue
Q2 2026168$2.22B
Q1 2026164$2.52B
Q4 2025133$1.49B
Q3 2025116$778.4M
Q2 2025121$541.5M
Q1 2025117$499.5M
Q4 2024113$675.8M
Q3 202495$1.11B
Q2 202479$748.6M
Q1 202477$768.4M
Q4 202362$495.2M
Q3 202359$502.1M
Q2 202359$616.7M
Q1 202351$573.0M
Q4 202246$267.8M
Q3 202249$313.8M
Q2 202248$255.6M
Q1 202246$386.6M
Q4 202145$494.2M
Q3 202126$456.8M
Q2 20210$0
Q1 20210$0

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q1 2025.

Institutions holding TYRA in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
GF Fund Management Co. Ltd.1,296$12.4K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.1,009$9.65K0.00%+174+20.8%Added
Versant Capital Management, Inc819$7.84K0.00%+819New
Amalgamated Bank701$7.00K0.00%00.0%Unchanged
STRS Ohio700$6.70K0.00%00.0%Unchanged
Sterling Capital Management LLC650$6.22K0.00%+629+2,995.2%Added
Caitong International Asset Management Co., Ltd569$5.45K0.00%+66+13.1%Added
Federated Hermes, Inc.314$3.00K0.00%−161−33.9%Reduced
GAMMA Investing LLC215$2.06K0.00%+215New
Daiwa Securities Group Inc.173$2.00K0.00%00.0%Unchanged
True Wealth Design, LLC142$1.36K0.00%+142New
Clearstead Advisors, LLC125$1.20K0.00%+125New
Allworth Financial LP100$9570.00%00.0%Unchanged
Nisa Investment Advisors, LLC86$8230.00%−63−42.3%Reduced
The PNC Financial Services Group, Inc.58$5550.00%00.0%Unchanged
Rothschild Investment LLC55$5260.00%+50+1,000.0%Added
Signaturefd, LLC43$4120.00%+43New
EverSource Wealth Advisors, LLC40$3830.00%+31+344.4%Added
Larson Financial Group LLC36$3450.00%+36New
SBI Securities Co., Ltd.4$380.00%00.0%Unchanged
Covestor Ltd6$00.00%00.0%Unchanged
Pictet Asset Management Holding SA0$00.00%−459,113−100.0%Sold out
Polar Asset Management Partners Inc.0$00.00%−141,241−100.0%Sold out
Ally Bridge Group (NY) LLC0$00.00%−107,244−100.0%Sold out
UBS Asset Management Americas Inc0$00.00%−35,635−100.0%Sold out
Ikarian Capital, LLC0$00.00%−35,000−100.0%Sold out
Swiss National Bank0$00.00%−29,400−100.0%Sold out
SG Americas Securities, LLC0$00.00%−15,120−100.0%Sold out
EntryPoint Capital, LLC0$00.00%−14,892−100.0%Sold out
Exchange Traded Concepts, LLC0$00.00%−11,861−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−9,590−100.0%Sold out
Zurcher Kantonalbank (Zurich Cantonalbank)0$00.00%−9,047−100.0%Sold out
KLP Kapitalforvaltning AS0$00.00%−2,200−100.0%Sold out
Coldstream Capital Management Inc0$00.00%−28−100.0%Sold out
CoreCap Advisors, LLC0$00.00%−16−100.0%Sold out