Tyra Biosciences, Inc.
TYRA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001863127
In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Tyra Biosciences, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 121
- +4 vs. Q1 2025
- Shares held
- 56.6M
- +3.02M (+5.6%) vs. Q1 2025
- Total value
- $541.5M
- +$42.0M (+8.4%) vs. Q1 2025
- New holders
- 18
- 62 more added
- Sold out
- 14
- 20 more reduced
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 168 | $2.22B |
| Q1 2026 | 164 | $2.52B |
| Q4 2025 | 133 | $1.49B |
| Q3 2025 | 116 | $778.4M |
| Q2 2025 | 121 | $541.5M |
| Q1 2025 | 117 | $499.5M |
| Q4 2024 | 113 | $675.8M |
| Q3 2024 | 95 | $1.11B |
| Q2 2024 | 79 | $748.6M |
| Q1 2024 | 77 | $768.4M |
| Q4 2023 | 62 | $495.2M |
| Q3 2023 | 59 | $502.1M |
| Q2 2023 | 59 | $616.7M |
| Q1 2023 | 51 | $573.0M |
| Q4 2022 | 46 | $267.8M |
| Q3 2022 | 49 | $313.8M |
| Q2 2022 | 48 | $255.6M |
| Q1 2022 | 46 | $386.6M |
| Q4 2021 | 45 | $494.2M |
| Q3 2021 | 26 | $456.8M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 6 | $0 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 4 | $38 | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 36 | $345 | 0.00% | +36 | New |
| EverSource Wealth Advisors, LLC | 40 | $383 | 0.00% | +31+344.4% | Added |
| Signaturefd, LLC | 43 | $412 | 0.00% | +43 | New |
| Rothschild Investment LLC | 55 | $526 | 0.00% | +50+1,000.0% | Added |
| The PNC Financial Services Group, Inc. | 58 | $555 | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 86 | $823 | 0.00% | −63−42.3% | Reduced |
| Allworth Financial LP | 100 | $957 | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 125 | $1.20K | 0.00% | +125 | New |
| True Wealth Design, LLC | 142 | $1.36K | 0.00% | +142 | New |
| Daiwa Securities Group Inc. | 173 | $2.00K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 215 | $2.06K | 0.00% | +215 | New |
| Federated Hermes, Inc. | 314 | $3.00K | 0.00% | −161−33.9% | Reduced |
| Caitong International Asset Management Co., Ltd | 569 | $5.45K | 0.00% | +66+13.1% | Added |
| Sterling Capital Management LLC | 650 | $6.22K | 0.00% | +629+2,995.2% | Added |
| STRS Ohio | 700 | $6.70K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 701 | $7.00K | 0.00% | 00.0% | Unchanged |
| Versant Capital Management, Inc | 819 | $7.84K | 0.00% | +819 | New |
| Advisor Group Holdings, Inc. | 1,009 | $9.65K | 0.00% | +174+20.8% | Added |
| GF Fund Management Co. Ltd. | 1,296 | $12.4K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 1,472 | $14.1K | 0.00% | −9,098−86.1% | Reduced |
| CWM, LLC | 1,541 | $15.0K | 0.00% | +1,158+302.3% | Added |
| Ameritas Investment Partners, Inc. | 1,991 | $19.1K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 2,054 | $19.7K | 0.00% | +361+21.3% | Added |
| Legal & General Group Plc | 2,192 | $21.0K | 0.00% | −7,069−76.3% | Reduced |
| Point72 (DIFC) Ltd | 2,330 | $22.3K | 0.00% | +57+2.5% | Added |
| Tower Research Capital LLC (TRC) | 2,840 | $27.2K | 0.00% | +757+36.3% | Added |
| Point72 Asia (Singapore) Pte. Ltd. | 3,490 | $33.4K | 0.01% | +2,698+340.7% | Added |
| Police & Firemen's Retirement System of New Jersey | 5,049 | $48.3K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 7,423 | $71.0K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 7,561 | $72.4K | 0.00% | +2,126+39.1% | Added |
| Virtus Investment Advisers, Inc. | 9,103 | $87.1K | 0.03% | −1,715−15.9% | Reduced |
| Citigroup Inc | 9,497 | $90.9K | 0.00% | −6,010−38.8% | Reduced |
| Russell Investments Group, Ltd. | 9,975 | $95.5K | 0.00% | −264−2.6% | Reduced |
| Baker Bros. Advisors LP | 10,607 | $101.5K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 10,681 | $102.2K | 0.01% | +531+5.2% | Added |
| Price T Rowe Associates Inc | 12,022 | $116.0K | 0.00% | +12,022 | New |
| FMR LLC | 12,202 | $116.8K | 0.00% | −1,694,946−99.3% | Reduced |
| Axq Capital, LP | 12,350 | $118.2K | 0.04% | +2,048+19.9% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 13,182 | $126.2K | 0.00% | +1,668+14.5% | Added |
| Deutsche Bank AG | 13,300 | $127.3K | 0.00% | −3,679−21.7% | Reduced |
| Aquatic Capital Management LLC | 13,744 | $131.5K | 0.00% | +1,963+16.7% | Added |
| MetLife Investment Management | 14,631 | $140.0K | 0.00% | +2,424+19.9% | Added |
| Wells Fargo & Company | 15,457 | $147.9K | 0.00% | +6,104+65.3% | Added |
| Royal Bank of Canada | 16,213 | $156.0K | 0.00% | +15,536+2,294.8% | Added |
| Public Employees Retirement System of Ohio | 18,512 | $177.2K | 0.00% | +18,512 | New |
| Intech Investment Management LLC | 19,919 | $190.6K | 0.00% | +6,322+46.5% | Added |
| Auour Investments LLC | 21,020 | $201.2K | 0.07% | 00.0% | Unchanged |
| Corton Capital Inc. | 24,346 | $233.0K | 0.27% | +24,346 | New |
| HighVista Strategies LLC | 24,962 | $238.9K | 0.09% | +1,021+4.3% | Added |
| Tudor Investment Corp Et Al | 26,265 | $251.4K | 0.00% | +14,172+117.2% | Added |
| AQR Capital Management LLC | 28,712 | $274.8K | 0.00% | +28,712 | New |
| Alps Advisors Inc | 28,729 | $274.9K | 0.00% | +28,729 | New |
| American Century Companies Inc | 28,854 | $276.1K | 0.00% | +5,423+23.1% | Added |
| Squarepoint Ops LLC | 31,408 | $300.6K | 0.00% | +31,408 | New |
| Dynamic Technology Lab Private Ltd | 34,115 | $326.0K | 0.04% | +34,115 | New |
| XTX Topco Ltd | 34,601 | $331.1K | 0.01% | +34,601 | New |
| Alliancebernstein L.P. | 35,640 | $341.1K | 0.00% | +18,070+102.8% | Added |
| Brevan Howard Capital Management LP | 36,594 | $350.2K | 0.00% | −9,777−21.1% | Reduced |
| Susquehanna International Group, LLP | 37,782 | $361.6K | 0.00% | +14,256+60.6% | Added |
| Rhumbline Advisers | 40,685 | $389.3K | 0.00% | +12,604+44.9% | Added |
| Verition Fund Management LLC | 40,939 | $391.8K | 0.00% | −1,235−2.9% | Reduced |
| Dimensional Fund Advisors LP | 41,681 | $398.9K | 0.00% | +6,969+20.1% | Added |
| PDT Partners, LLC | 43,310 | $414.5K | 0.02% | +43,310 | New |
| Victory Capital Management Inc | 44,190 | $422.9K | 0.00% | −11,960−21.3% | Reduced |
| Trexquant Investment LP | 44,681 | $427.6K | 0.00% | +44,681 | New |
| UBS Group AG | 46,268 | $442.8K | 0.00% | −180.0% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 48,644 | $465.5K | 0.01% | +48,644 | New |
| Bank of New York Mellon Corp | 54,039 | $517.2K | 0.00% | +12,956+31.5% | Added |
| Jane Street Group, LLC | 58,168 | $556.7K | 0.00% | +23,355+67.1% | Added |
| Barclays PLC | 61,555 | $589.1K | 0.00% | +19,044+44.8% | Added |
| Raymond James Financial Inc | 63,187 | $604.7K | 0.00% | +8,843+16.3% | Added |
| ExodusPoint Capital Management, LP | 67,442 | $645.0K | 0.01% | +37,207+123.1% | Added |
| Jump Financial, LLC | 71,119 | $680.6K | 0.01% | +43,170+154.5% | Added |
| Quest Partners LLC | 73,073 | $699.3K | 0.07% | +43,451+146.7% | Added |
| Oppenheimer & Co Inc | 74,033 | $708.5K | 0.01% | −772−1.0% | Reduced |
| State of Wisconsin Investment Board | 76,449 | $731.6K | 0.00% | +17,737+30.2% | Added |
| Nuveen, LLC | 80,441 | $769.8K | 0.00% | +30,443+60.9% | Added |
| Ameriprise Financial Inc | 80,602 | $771.4K | 0.00% | +80,602 | New |
| Investment Counsel Co of Nevada | 85,020 | $813.6K | 1.67% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 87,000 | $832.6K | 0.00% | +36,900+73.7% | Added |
| BNP Paribas Arbitrage, SA | 97,736 | $935.3K | 0.00% | +28,786+41.7% | Added |
| Woodline Partners LP | 100,108 | $958.0K | 0.01% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 102,917 | $984.9K | 0.00% | +17,427+20.4% | Added |
| Wellington Management Group LLP | 103,078 | $986.5K | 0.00% | −1,009−1.0% | Reduced |
| Goldman Sachs Group Inc | 105,595 | $1.01M | 0.00% | +27,589+35.4% | Added |
| Two Sigma Investments, LP | 105,825 | $1.01M | 0.00% | +41,007+63.3% | Added |
| Cubist Systematic Strategies, LLC | 122,036 | $1.17M | 0.01% | +30,192+32.9% | Added |
| AXA S.A. | 128,400 | $1.23M | 0.00% | +211+0.2% | Added |
| Renaissance Technologies LLC | 135,100 | $1.29M | 0.00% | +83,700+162.8% | Added |
| Charles Schwab Investment Management Inc | 178,104 | $1.70M | 0.00% | +13,996+8.5% | Added |
| Caligan Partners LP | 189,950 | $1.82M | 0.35% | +164,950+659.8% | Added |
| Northern Trust Corp | 205,308 | $1.96M | 0.00% | −11,139−5.1% | Reduced |
| Citadel Advisors LLC | 216,136 | $2.07M | 0.00% | +119,854+124.5% | Added |
| Point72 Asset Management, L.P. | 224,700 | $2.15M | 0.01% | +175,100+353.0% | Added |
| Walleye Capital LLC | 370,408 | $3.54M | 0.03% | +229,666+163.2% | Added |
| Bank of America Corp | 372,967 | $3.57M | 0.00% | +289,446+346.6% | Added |
| Morgan Stanley | 378,402 | $3.62M | 0.00% | +197,812+109.5% | Added |
| Jacobs Levy Equity Management, Inc | 395,299 | $3.78M | 0.01% | +93,498+31.0% | Added |