Spruce Biosciences, Inc.
SPRB- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001683553
No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.
13F holders, Q3 2024
Institutional positions in Spruce Biosciences, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 30
- −7 vs. Q2 2024
- Shares held
- 13.6M
- −2.85M (−17.3%) vs. Q2 2024
- Total value
- $6.41M
- −$2.14M (−25.0%) vs. Q2 2024
- New holders
- 1
- 6 more added
- Sold out
- 8
- 11 more reduced
1 institution that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SPRB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 65 | $116.3M |
| Q1 2026 | 32 | $48.3M |
| Q4 2025 | 32 | $65.6M |
| Q3 2025 | 9 | $25.1M |
| Q2 2025 | 3 | $146.6K |
| Q1 2025 | 31 | $3.03M |
| Q4 2024 | 31 | $4.69M |
| Q3 2024 | 30 | $6.41M |
| Q2 2024 | 38 | $8.61M |
| Q1 2024 | 50 | $14.1M |
| Q4 2023 | 40 | $94.4M |
| Q3 2023 | 41 | $72.0M |
| Q2 2023 | 39 | $68.7M |
| Q1 2023 | 44 | $74.5M |
| Q4 2022 | 31 | $20.0M |
| Q3 2022 | 36 | $24.7M |
| Q2 2022 | 38 | $28.5M |
| Q1 2022 | 43 | $34.4M |
| Q4 2021 | 50 | $79.0M |
| Q3 2021 | 44 | $118.1M |
| Q2 2021 | 41 | $225.3M |
| Q1 2021 | 40 | $313.2M |
Institutions, Q3 2024
Shares, value and share of portfolio for each institution holding Spruce Biosciences, Inc.; share changes are against Q2 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| UBS Group AG | 13 | $6 | 0.00% | −131,910−100.0% | Reduced |
| JPMorgan Chase & Co | 71 | $33 | 0.00% | −1−1.4% | Reduced |
| Bank of America Corp | 223 | $106 | 0.00% | +73+48.7% | Added |
| Caldwell Sutter Capital, Inc. | 1,000 | $475 | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 2,133 | $1.01K | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 3,839 | $1.82K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 3,733 | $2.00K | 0.00% | +3,517+1,628.2% | Added |
| Tower Research Capital LLC (TRC) | 4,650 | $2.21K | 0.00% | −28,437−85.9% | Reduced |
| Marex Group plc | 14,800 | $7.03K | 0.00% | 00.0% | Unchanged |
| Jane Street Group, LLC | 15,658 | $7.44K | 0.00% | −15,190−49.2% | Reduced |
| XTX Topco Ltd | 19,134 | $9.09K | 0.00% | −8,051−29.6% | Reduced |
| Two Sigma Investments, LP | 23,368 | $11.1K | 0.00% | −5,216−18.2% | Reduced |
| Two Sigma Advisers, LP | 27,100 | $12.9K | 0.00% | −18,600−40.7% | Reduced |
| Shay Capital LLC | 38,119 | $18.1K | 0.01% | +24,947+189.4% | Added |
| Bridgeway Capital Management, LLC | 40,000 | $19.0K | 0.00% | −45,000−52.9% | Reduced |
| State Street Corp | 64,400 | $30.6K | 0.00% | 00.0% | Unchanged |
| Northern Trust Corp | 74,927 | $35.6K | 0.00% | 00.0% | Unchanged |
| Lion Point Capital, LP | 75,000 | $35.6K | 0.14% | 00.0% | Unchanged |
| Citadel Advisors LLC | 77,053 | $36.6K | 0.00% | −7,662−9.0% | Reduced |
| BlackRock, Inc. | 124,734 | $59.2K | 0.00% | +124,734 | New |
| Geode Capital Management, LLC | 261,948 | $124.4K | 0.00% | +57,946+28.4% | Added |
| Almitas Capital LLC | 396,506 | $188.3K | 0.07% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 403,716 | $191.7K | 0.03% | +48,500+13.7% | Added |
| Renaissance Technologies LLC | 609,700 | $289.5K | 0.00% | +243,600+66.5% | Added |
| Sands Capital Ventures, LLC | 787,007 | $369.9K | 0.10% | 00.0% | Unchanged |
| Vanguard Group Inc | 843,844 | $400.8K | 0.00% | −19,531−2.3% | Reduced |
| Acadian Asset Management LLC | 1,259,151 | $597.0K | 0.00% | −108,846−8.0% | Reduced |
| Rock Springs Capital Management LP | 2,609,125 | $1.24M | 0.04% | 00.0% | Unchanged |
| Carlyle Group Inc. | 2,896,518 | $1.32M | 0.14% | 00.0% | Unchanged |
| RiverVest Venture Management LLC | 2,936,281 | $1.39M | 20.39% | 00.0% | Unchanged |
| Rosalind Advisors, Inc. | 0 | $0 | 0.00% | −1,508,419−100.0% | Sold out |
| Altium Capital Management LP | 0 | $0 | 0.00% | −811,167−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −386,702−100.0% | Sold out |
| 683 Capital Management, LLC | 0 | $0 | 0.00% | −140,934−100.0% | Sold out |
| Superstring Capital Management LP | 0 | $0 | 0.00% | −77,992−100.0% | Sold out |
| Privium Fund Management (UK) Ltd | 0 | $0 | 0.00% | −24,554−100.0% | Sold out |
| Charles Schwab Investment Management Inc | 0 | $0 | 0.00% | −15,289−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| BlackRock Inc. | – | – | – | – | Not filed |