Spruce Biosciences, Inc.
SPRB- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001683553
No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.
13F holders, Q2 2022
Institutional positions in Spruce Biosciences, Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 38
- −3 vs. Q1 2022
- Shares held
- 16.4M
- −684.4K (−4.0%) vs. Q1 2022
- Total value
- $28.5M
- −$5.80M (−16.9%) vs. Q1 2022
- New holders
- 7
- 6 more added
- Sold out
- 10
- 16 more reduced
2 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SPRB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 65 | $116.3M |
| Q1 2026 | 32 | $48.8M |
| Q4 2025 | 32 | $65.6M |
| Q3 2025 | 9 | $25.1M |
| Q2 2025 | 3 | $146.6K |
| Q1 2025 | 31 | $3.03M |
| Q4 2024 | 31 | $4.69M |
| Q3 2024 | 30 | $6.41M |
| Q2 2024 | 38 | $8.61M |
| Q1 2024 | 50 | $14.2M |
| Q4 2023 | 40 | $94.4M |
| Q3 2023 | 41 | $72.0M |
| Q2 2023 | 39 | $68.7M |
| Q1 2023 | 44 | $74.5M |
| Q4 2022 | 31 | $20.0M |
| Q3 2022 | 36 | $24.7M |
| Q2 2022 | 38 | $28.5M |
| Q1 2022 | 43 | $34.4M |
| Q4 2021 | 50 | $79.1M |
| Q3 2021 | 44 | $118.1M |
| Q2 2021 | 41 | $225.3M |
| Q1 2021 | 40 | $313.2M |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Spruce Biosciences, Inc.; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Novo Holdings A/S | 4,514,336 | $7.86M | 0.39% | 00.0% | Unchanged |
| Omega Fund Management, LLC | 2,161,022 | $3.76M | 1.20% | 00.0% | Unchanged |
| RiverVest Venture Management LLC | 2,148,281 | $3.74M | 5.49% | 00.0% | Unchanged |
| Citadel Advisors LLC | 1,724,453 | $3.00M | 0.00% | +2,607+0.2% | Added |
| Rock Springs Capital Management LP | 1,622,689 | $2.82M | 0.08% | 00.0% | Unchanged |
| Aisling Capital Management LP | 1,205,511 | $2.10M | 1.50% | 00.0% | Unchanged |
| Logos Global Management LP | 1,000,000 | $1.74M | 0.32% | 00.0% | Unchanged |
| Sands Capital Ventures, LLC | 787,007 | $1.37M | 0.38% | 00.0% | Unchanged |
| Millennium Management LLC | 190,147 | $331.0K | 0.00% | +190,147 | New |
| BlackRock Inc. | 156,039 | $272.0K | 0.00% | −373,515−70.5% | Reduced |
| Renaissance Technologies LLC | 151,400 | $263.0K | 0.00% | +39,700+35.5% | Added |
| Vanguard Group Inc | 116,058 | $202.0K | 0.00% | −37,678−24.5% | Reduced |
| State Street Corp | 93,100 | $162.0K | 0.00% | −112,359−54.7% | Reduced |
| Bank of New York Mellon Corp | 92,764 | $161.0K | 0.00% | −23,737−20.4% | Reduced |
| Marquette Asset Management, LLC | 64,090 | $112.0K | 0.03% | +23,237+56.9% | Added |
| Morgan Stanley | 60,660 | $106.0K | 0.00% | +49,239+431.1% | Added |
| Geode Capital Management, LLC | 60,755 | $105.0K | 0.00% | −66,273−52.2% | Reduced |
| Bridgeway Capital Management, LLC | 60,000 | $104.0K | 0.00% | −186,327−75.6% | Reduced |
| Goldman Sachs Group Inc | 59,609 | $104.0K | 0.00% | +16,941+39.7% | Added |
| Ergoteles LLC | 41,900 | $73.0K | 0.00% | +41,900 | New |
| Virtu Financial LLC | 15,738 | $27.0K | 0.00% | +15,738 | New |
| Northern Trust Corp | 14,067 | $24.0K | 0.00% | −56,620−80.1% | Reduced |
| StoneX Group Inc. | 11,900 | $20.7K | 0.00% | +11,900 | New |
| Barclays PLC | 11,442 | $20.0K | 0.00% | −1,249−9.8% | Reduced |
| UBS Group AG | 5,848 | $10.0K | 0.00% | +1,940+49.6% | Added |
| Tower Research Capital LLC (TRC) | 3,023 | $5.00K | 0.00% | −2,319−43.4% | Reduced |
| Bank of America Corp | 2,849 | $5.00K | 0.00% | −2,062−42.0% | Reduced |
| Wells Fargo & Company | 1,059 | $2.00K | 0.00% | −3,793−78.2% | Reduced |
| Federated Hermes, Inc. | 988 | $2.00K | 0.00% | +988 | New |
| FMR LLC | 415 | $1.00K | 0.00% | −6,564−94.1% | Reduced |
| Citigroup Inc | 393 | $1.00K | 0.00% | −793−66.9% | Reduced |
| Legal & General Group Plc | 782 | $1.00K | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 11 | $0 | 0.00% | −113,370−100.0% | Reduced |
| New York State Common Retirement Fund | 77 | $0 | 0.00% | −5,923−98.7% | Reduced |
| Royal Bank of Canada | 170 | $0 | 0.00% | −463−73.1% | Reduced |
| TCI Wealth Advisors, Inc. | 250 | $0 | 0.00% | 00.0% | Unchanged |
| Credit Suisse AG | 5 | $0 | 0.00% | +5 | New |
| Capital Advisors, Ltd. LLC | 119 | $0 | 0.00% | +119 | New |
| Charles Schwab Investment Management Inc | 0 | $0 | 0.00% | −18,417−100.0% | Sold out |
| State Board of Administration of Florida Retirement System | 0 | $0 | 0.00% | −17,440−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −13,202−100.0% | Sold out |
| Deutsche Bank AG | 0 | $0 | 0.00% | −12,297−100.0% | Sold out |
| Nuveen Asset Management, LLC | 0 | $0 | 0.00% | −11,643−100.0% | Sold out |
| American International Group, Inc. | 0 | $0 | 0.00% | −4,312−100.0% | Sold out |
| California State Teachers Retirement System | 0 | $0 | 0.00% | −3,936−100.0% | Sold out |
| Point72 Hong Kong Ltd | 0 | $0 | 0.00% | −2,881−100.0% | Sold out |
| Amalgamated Bank | 0 | $0 | 0.00% | −1,084−100.0% | Sold out |
| Ameritas Investment Partners, Inc. | 0 | $0 | 0.00% | −584−100.0% | Sold out |
| Parametric Portfolio Associates LLC | – | – | – | – | Not filed |
| Amalgamated Financial Corp. | – | – | – | – | Not filed |