Spruce Biosciences, Inc.
SPRB- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001683553
No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.
13F holders, Q3 2023
Institutional positions in Spruce Biosciences, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 41
- +2 vs. Q2 2023
- Shares held
- 31.9M
- −78.4K (−0.2%) vs. Q2 2023
- Total value
- $72.0M
- +$3.25M (+4.7%) vs. Q2 2023
- New holders
- 2
- 11 more added
- Sold out
- 0
- 11 more reduced
Compare with Q2 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SPRB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 65 | $116.3M |
| Q1 2026 | 32 | $48.3M |
| Q4 2025 | 32 | $65.6M |
| Q3 2025 | 9 | $25.1M |
| Q2 2025 | 3 | $146.6K |
| Q1 2025 | 31 | $3.03M |
| Q4 2024 | 31 | $4.69M |
| Q3 2024 | 30 | $6.41M |
| Q2 2024 | 38 | $8.61M |
| Q1 2024 | 50 | $14.1M |
| Q4 2023 | 40 | $94.4M |
| Q3 2023 | 41 | $72.0M |
| Q2 2023 | 39 | $68.7M |
| Q1 2023 | 44 | $74.5M |
| Q4 2022 | 31 | $20.0M |
| Q3 2022 | 36 | $24.7M |
| Q2 2022 | 38 | $28.5M |
| Q1 2022 | 43 | $34.4M |
| Q4 2021 | 50 | $79.0M |
| Q3 2021 | 44 | $118.1M |
| Q2 2021 | 41 | $225.3M |
| Q1 2021 | 40 | $313.2M |
Institutions, Q3 2023
Shares, value and share of portfolio for each institution holding Spruce Biosciences, Inc.; share changes are against Q2 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Novo Holdings A/S | 6,722,336 | $15.2M | 1.12% | 00.0% | Unchanged |
| Armistice Capital, LLC | 3,056,000 | $6.91M | 0.21% | −442,000−12.6% | Reduced |
| RiverVest Venture Management LLC | 2,936,281 | $6.64M | 16.41% | 00.0% | Unchanged |
| Carlyle Group Inc. | 2,896,518 | $6.46M | 0.28% | 00.0% | Unchanged |
| Rock Springs Capital Management LP | 2,728,125 | $6.17M | 0.17% | 00.0% | Unchanged |
| 5AM Venture Management, LLC | 2,364,000 | $5.34M | 1.54% | 00.0% | Unchanged |
| Omega Fund Management, LLC | 2,161,022 | $4.88M | 4.49% | 00.0% | Unchanged |
| Verition Fund Management LLC | 1,319,393 | $2.98M | 0.04% | +235,663+21.7% | Added |
| AIGH Capital Management LLC | 1,211,000 | $2.74M | 1.30% | +100,000+9.0% | Added |
| Aisling Capital Management LP | 1,205,511 | $2.72M | 1.12% | 00.0% | Unchanged |
| Alyeska Investment Group, L.P. | 1,000,000 | $2.26M | 0.02% | 00.0% | Unchanged |
| Sands Capital Ventures, LLC | 787,007 | $1.78M | 0.53% | 00.0% | Unchanged |
| Millennium Management LLC | 583,472 | $1.32M | 0.00% | +5,814+1.0% | Added |
| DAFNA Capital Management LLC | 570,130 | $1.29M | 0.40% | +258,130+82.7% | Added |
| Vanguard Group Inc | 328,269 | $741.9K | 0.00% | +66,315+25.3% | Added |
| Worth Venture Partners, LLC | 302,074 | $682.7K | 0.41% | +24,450+8.8% | Added |
| Acuitas Investments, LLC | 275,001 | $621.5K | 0.37% | −50.0% | Reduced |
| BlackRock Inc. | 258,501 | $584.2K | 0.00% | −2,478−0.9% | Reduced |
| Renaissance Technologies LLC | 207,776 | $470.0K | 0.00% | −31,323−13.1% | Reduced |
| Geode Capital Management, LLC | 167,404 | $378.4K | 0.00% | −50,507−23.2% | Reduced |
| Two Sigma Investments, LP | 147,357 | $333.0K | 0.00% | −80,773−35.4% | Reduced |
| Two Sigma Advisers, LP | 96,300 | $217.6K | 0.00% | −143,700−59.9% | Reduced |
| Bank of New York Mellon Corp | 89,120 | $201.4K | 0.00% | −2,335−2.6% | Reduced |
| Bridgeway Capital Management, LLC | 85,000 | $192.1K | 0.00% | 00.0% | Unchanged |
| Citadel Advisors LLC | 75,030 | $169.6K | 0.00% | +3,753+5.3% | Added |
| State Street Corp | 61,993 | $140.1K | 0.00% | +3,200+5.4% | Added |
| Sofinnova Investments, Inc. | 58,029 | $131.1K | 0.01% | 00.0% | Unchanged |
| Marquette Asset Management, LLC | 55,757 | $126.0K | 0.03% | 00.0% | Unchanged |
| Northern Trust Corp | 48,664 | $110.0K | 0.00% | −8,433−14.8% | Reduced |
| Dimensional Fund Advisors LP | 32,452 | $73.3K | 0.00% | +120.0% | Added |
| Privium Fund Management (UK) Ltd | 24,554 | $54.8K | 0.04% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 15,289 | $34.6K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 9,651 | $22.0K | 0.00% | +7,120+281.3% | Added |
| Tower Research Capital LLC (TRC) | 4,356 | $9.85K | 0.00% | +1,998+84.7% | Added |
| Morgan Stanley | 2,131 | $4.82K | 0.00% | 00.0% | Unchanged |
| Caldwell Sutter Capital, Inc. | 1,000 | $2.26K | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 310 | $701 | 0.00% | +310 | New |
| Wells Fargo & Company | 130 | $294 | 0.00% | −56−30.1% | Reduced |
| FMR LLC | 36 | $82 | 0.00% | +36 | New |
| UBS Group AG | 13 | $29 | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 11 | $25 | 0.00% | −23,549−100.0% | Reduced |