Spruce Biosciences, Inc.
SPRB- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001683553
No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.
13F holders, Q2 2024
Institutional positions in Spruce Biosciences, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 38
- −12 vs. Q1 2024
- Shares held
- 16.6M
- −1.38M (−7.7%) vs. Q1 2024
- Total value
- $8.61M
- −$5.51M (−39.0%) vs. Q1 2024
- New holders
- 5
- 7 more added
- Sold out
- 17
- 14 more reduced
Compare with Q1 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SPRB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 65 | $116.3M |
| Q1 2026 | 32 | $48.3M |
| Q4 2025 | 32 | $65.6M |
| Q3 2025 | 9 | $25.1M |
| Q2 2025 | 3 | $146.6K |
| Q1 2025 | 31 | $3.03M |
| Q4 2024 | 31 | $4.69M |
| Q3 2024 | 30 | $6.41M |
| Q2 2024 | 38 | $8.61M |
| Q1 2024 | 50 | $14.1M |
| Q4 2023 | 40 | $94.4M |
| Q3 2023 | 41 | $72.0M |
| Q2 2023 | 39 | $68.7M |
| Q1 2023 | 44 | $74.5M |
| Q4 2022 | 31 | $20.0M |
| Q3 2022 | 36 | $24.7M |
| Q2 2022 | 38 | $28.5M |
| Q1 2022 | 43 | $34.4M |
| Q4 2021 | 50 | $79.0M |
| Q3 2021 | 44 | $118.1M |
| Q2 2021 | 41 | $225.3M |
| Q1 2021 | 40 | $313.2M |
Institutions, Q2 2024
Shares, value and share of portfolio for each institution holding Spruce Biosciences, Inc.; share changes are against Q1 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| RiverVest Venture Management LLC | 2,936,281 | $1.52M | 22.27% | 00.0% | Unchanged |
| Carlyle Group Inc. | 2,896,518 | $1.52M | 0.14% | 00.0% | Unchanged |
| Rock Springs Capital Management LP | 2,609,125 | $1.35M | 0.04% | 00.0% | Unchanged |
| Rosalind Advisors, Inc. | 1,508,419 | $780.9K | 0.62% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 1,367,997 | $707.0K | 0.00% | +999,166+270.9% | Added |
| Vanguard Group Inc | 863,375 | $447.0K | 0.00% | 00.0% | Unchanged |
| Altium Capital Management LP | 811,167 | $419.9K | 0.17% | −338,833−29.5% | Reduced |
| Sands Capital Ventures, LLC | 787,007 | $409.2K | 0.14% | 00.0% | Unchanged |
| Almitas Capital LLC | 396,506 | $205.3K | 0.09% | +396,506 | New |
| ExodusPoint Capital Management, LP | 386,702 | $200.0K | 0.00% | +161,869+72.0% | Added |
| Renaissance Technologies LLC | 366,100 | $189.5K | 0.00% | +95,100+35.1% | Added |
| ADAR1 Capital Management, LLC | 355,216 | $183.9K | 0.04% | −10,000−2.7% | Reduced |
| Geode Capital Management, LLC | 204,002 | $105.6K | 0.00% | +3,840+1.9% | Added |
| 683 Capital Management, LLC | 140,934 | $73.0K | 0.01% | +140,934 | New |
| UBS Group AG | 131,923 | $68.3K | 0.00% | +116,109+734.2% | Added |
| BlackRock Inc. | 124,734 | $64.6K | 0.00% | −61,214−32.9% | Reduced |
| Bridgeway Capital Management, LLC | 85,000 | $44.0K | 0.00% | 00.0% | Unchanged |
| Citadel Advisors LLC | 84,715 | $43.9K | 0.00% | −3,162−3.6% | Reduced |
| Superstring Capital Management LP | 77,992 | $40.4K | 0.05% | −362,233−82.3% | Reduced |
| Lion Point Capital, LP | 75,000 | $38.8K | 0.12% | 00.0% | Unchanged |
| Northern Trust Corp | 74,927 | $38.8K | 0.00% | −280.0% | Reduced |
| State Street Corp | 64,400 | $33.3K | 0.00% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 45,700 | $23.7K | 0.00% | −44,600−49.4% | Reduced |
| Tower Research Capital LLC (TRC) | 33,087 | $17.1K | 0.00% | +21,660+189.6% | Added |
| Jane Street Group, LLC | 30,848 | $16.0K | 0.00% | −47,696−60.7% | Reduced |
| Two Sigma Investments, LP | 28,584 | $14.8K | 0.00% | −94,429−76.8% | Reduced |
| XTX Topco Ltd | 27,185 | $14.1K | 0.00% | −29,562−52.1% | Reduced |
| Privium Fund Management (UK) Ltd | 24,554 | $12.9K | 0.01% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 15,289 | $7.92K | 0.00% | 00.0% | Unchanged |
| Marex Group plc | 14,800 | $7.66K | 0.00% | +14,800 | New |
| Shay Capital LLC | 13,172 | $6.82K | 0.00% | +13,172 | New |
| Group One Trading, L.P. | 3,839 | $1.99K | 0.00% | −100−2.5% | Reduced |
| Morgan Stanley | 2,133 | $1.10K | 0.00% | −19,390−90.1% | Reduced |
| Caldwell Sutter Capital, Inc. | 1,000 | $518 | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 150 | $78 | 0.00% | −25,980−99.4% | Reduced |
| JPMorgan Chase & Co | 72 | $38 | 0.00% | +61+554.5% | Added |
| Qube Research & Technologies Ltd | 2 | $1 | 0.00% | −39,594−100.0% | Reduced |
| Royal Bank of Canada | 216 | $0 | 0.00% | +216 | New |
| Aisling Capital Management LP | 0 | $0 | 0.00% | −1,205,511−100.0% | Sold out |
| Panagora Asset Management Inc | 0 | $0 | 0.00% | −253,682−100.0% | Sold out |
| AWM Investment Company, Inc. | 0 | $0 | 0.00% | −200,000−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −178,958−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −102,223−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −72,245−100.0% | Sold out |
| Castleview Partners, LLC | 0 | $0 | 0.00% | −59,709−100.0% | Sold out |
| Dimensional Fund Advisors LP | 0 | $0 | 0.00% | −46,664−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −29,709−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −28,100−100.0% | Sold out |
| Two Sigma Securities, LLC | 0 | $0 | 0.00% | −26,016−100.0% | Sold out |
| Belvedere Trading LLC | 0 | $0 | 0.00% | −24,900−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −22,508−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −16,000−100.0% | Sold out |
| Wells Fargo & Company | 0 | $0 | 0.00% | −143−100.0% | Sold out |
| FMR LLC | 0 | $0 | 0.00% | −103−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −362−100.0% | Sold out |