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Spruce Biosciences, Inc.

SPRB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001683553

No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.

13F holders, Q3 2024

Institutional positions in Spruce Biosciences, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
30
−7 vs. Q2 2024
Shares held
13.6M
−2.85M (−17.3%) vs. Q2 2024
Total value
$6.41M
−$2.14M (−25.0%) vs. Q2 2024
New holders
1
6 more added
Sold out
8
11 more reduced

1 institution that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SPRB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 30 institutions
Q1 2021: 40 institutionsQ2 2021: 41 institutionsQ3 2021: 44 institutionsQ4 2021: 50 institutionsQ1 2022: 43 institutionsQ2 2022: 38 institutionsQ3 2022: 36 institutionsQ4 2022: 31 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 41 institutionsQ4 2023: 40 institutionsQ1 2024: 50 institutionsQ2 2024: 38 institutionsQ3 2024: 30 institutionsQ4 2024: 31 institutionsQ1 2025: 31 institutionsQ2 2025: 3 institutionsQ3 2025: 9 institutionsQ4 2025: 32 institutionsQ1 2026: 32 institutionsQ2 2026: 65 institutions
Value heldQ3 2024: $6.41M
Q1 2021: $313.2MQ2 2021: $225.3MQ3 2021: $118.1MQ4 2021: $79.0MQ1 2022: $34.4MQ2 2022: $28.5MQ3 2022: $24.7MQ4 2022: $20.0MQ1 2023: $74.5MQ2 2023: $68.7MQ3 2023: $72.0MQ4 2023: $94.4MQ1 2024: $14.1MQ2 2024: $8.61MQ3 2024: $6.41MQ4 2024: $4.69MQ1 2025: $3.03MQ2 2025: $146.6KQ3 2025: $25.1MQ4 2025: $65.6MQ1 2026: $48.3MQ2 2026: $116.3M
Institutions holding SPRB and their total value by quarter
QuarterHoldersValue
Q2 202665$116.3M
Q1 202632$48.3M
Q4 202532$65.6M
Q3 20259$25.1M
Q2 20253$146.6K
Q1 202531$3.03M
Q4 202431$4.69M
Q3 202430$6.41M
Q2 202438$8.61M
Q1 202450$14.1M
Q4 202340$94.4M
Q3 202341$72.0M
Q2 202339$68.7M
Q1 202344$74.5M
Q4 202231$20.0M
Q3 202236$24.7M
Q2 202238$28.5M
Q1 202243$34.4M
Q4 202150$79.0M
Q3 202144$118.1M
Q2 202141$225.3M
Q1 202140$313.2M

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Spruce Biosciences, Inc.; share changes are against Q2 2024.

Institutions holding SPRB in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
RiverVest Venture Management LLC2,936,281$1.39M20.39%00.0%Unchanged
Carlyle Group Inc.2,896,518$1.32M0.14%00.0%Unchanged
Rock Springs Capital Management LP2,609,125$1.24M0.04%00.0%Unchanged
Acadian Asset Management LLC1,259,151$597.0K0.00%−108,846−8.0%Reduced
Vanguard Group Inc843,844$400.8K0.00%−19,531−2.3%Reduced
Sands Capital Ventures, LLC787,007$369.9K0.10%00.0%Unchanged
Renaissance Technologies LLC609,700$289.5K0.00%+243,600+66.5%Added
ADAR1 Capital Management, LLC403,716$191.7K0.03%+48,500+13.7%Added
Almitas Capital LLC396,506$188.3K0.07%00.0%Unchanged
Geode Capital Management, LLC261,948$124.4K0.00%+57,946+28.4%Added
BlackRock, Inc.124,734$59.2K0.00%+124,734New
Citadel Advisors LLC77,053$36.6K0.00%−7,662−9.0%Reduced
Lion Point Capital, LP75,000$35.6K0.14%00.0%Unchanged
Northern Trust Corp74,927$35.6K0.00%00.0%Unchanged
State Street Corp64,400$30.6K0.00%00.0%Unchanged
Bridgeway Capital Management, LLC40,000$19.0K0.00%−45,000−52.9%Reduced
Shay Capital LLC38,119$18.1K0.01%+24,947+189.4%Added
Two Sigma Advisers, LP27,100$12.9K0.00%−18,600−40.7%Reduced
Two Sigma Investments, LP23,368$11.1K0.00%−5,216−18.2%Reduced
XTX Topco Ltd19,134$9.09K0.00%−8,051−29.6%Reduced
Jane Street Group, LLC15,658$7.44K0.00%−15,190−49.2%Reduced
Marex Group plc14,800$7.03K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)4,650$2.21K0.00%−28,437−85.9%Reduced
Royal Bank of Canada3,733$2.00K0.00%+3,517+1,628.2%Added
Group One Trading, L.P.3,839$1.82K0.00%00.0%Unchanged
Morgan Stanley2,133$1.01K0.00%00.0%Unchanged
Caldwell Sutter Capital, Inc.1,000$4750.00%00.0%Unchanged
Bank of America Corp223$1060.00%+73+48.7%Added
JPMorgan Chase & Co71$330.00%−1−1.4%Reduced
UBS Group AG13$60.00%−131,910−100.0%Reduced
Rosalind Advisors, Inc.0$00.00%−1,508,419−100.0%Sold out
Altium Capital Management LP0$00.00%−811,167−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−386,702−100.0%Sold out
683 Capital Management, LLC0$00.00%−140,934−100.0%Sold out
Superstring Capital Management LP0$00.00%−77,992−100.0%Sold out
Privium Fund Management (UK) Ltd0$00.00%−24,554−100.0%Sold out
Charles Schwab Investment Management Inc0$00.00%−15,289−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−2−100.0%Sold out
BlackRock Inc.––––Not filed