Spruce Biosciences, Inc.
SPRB- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001683553
No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.
13F holders, Q3 2022
Institutional positions in Spruce Biosciences, Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 36
- −2 vs. Q2 2022
- Shares held
- 18.0M
- +1.67M (+10.2%) vs. Q2 2022
- Total value
- $24.7M
- −$3.75M (−13.2%) vs. Q2 2022
- New holders
- 3
- 7 more added
- Sold out
- 5
- 10 more reduced
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SPRB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 65 | $116.3M |
| Q1 2026 | 32 | $48.3M |
| Q4 2025 | 32 | $65.6M |
| Q3 2025 | 9 | $25.1M |
| Q2 2025 | 3 | $146.6K |
| Q1 2025 | 31 | $3.03M |
| Q4 2024 | 31 | $4.69M |
| Q3 2024 | 30 | $6.41M |
| Q2 2024 | 38 | $8.61M |
| Q1 2024 | 50 | $14.1M |
| Q4 2023 | 40 | $94.4M |
| Q3 2023 | 41 | $72.0M |
| Q2 2023 | 39 | $68.7M |
| Q1 2023 | 44 | $74.5M |
| Q4 2022 | 31 | $20.0M |
| Q3 2022 | 36 | $24.7M |
| Q2 2022 | 38 | $28.5M |
| Q1 2022 | 43 | $34.4M |
| Q4 2021 | 50 | $79.0M |
| Q3 2021 | 44 | $118.1M |
| Q2 2021 | 41 | $225.3M |
| Q1 2021 | 40 | $313.2M |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Spruce Biosciences, Inc.; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Novo Holdings A/S | 4,514,336 | $6.18M | 0.30% | 00.0% | Unchanged |
| Omega Fund Management, LLC | 2,161,022 | $2.96M | 1.08% | 00.0% | Unchanged |
| RiverVest Venture Management LLC | 2,148,281 | $2.94M | 3.42% | 00.0% | Unchanged |
| Abingworth LLP | 1,792,518 | $2.47M | 0.85% | +1,792,518 | New |
| Citadel Advisors LLC | 1,729,543 | $2.37M | 0.00% | +5,090+0.3% | Added |
| Rock Springs Capital Management LP | 1,622,689 | $2.22M | 0.06% | 00.0% | Unchanged |
| Aisling Capital Management LP | 1,205,511 | $1.65M | 1.10% | 00.0% | Unchanged |
| Logos Global Management LP | 1,000,000 | $1.37M | 0.17% | 00.0% | Unchanged |
| Sands Capital Ventures, LLC | 787,007 | $1.08M | 0.31% | 00.0% | Unchanged |
| BlackRock Inc. | 149,823 | $205.0K | 0.00% | −6,216−4.0% | Reduced |
| Millennium Management LLC | 145,015 | $199.0K | 0.00% | −45,132−23.7% | Reduced |
| Renaissance Technologies LLC | 143,100 | $196.0K | 0.00% | −8,300−5.5% | Reduced |
| Vanguard Group Inc | 124,979 | $171.0K | 0.00% | +8,921+7.7% | Added |
| State Street Corp | 93,100 | $128.0K | 0.00% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 92,764 | $127.0K | 0.00% | 00.0% | Unchanged |
| Marquette Asset Management, LLC | 64,090 | $88.0K | 0.03% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 60,755 | $83.0K | 0.00% | 00.0% | Unchanged |
| Bridgeway Capital Management, LLC | 60,000 | $82.0K | 0.00% | 00.0% | Unchanged |
| Ergoteles LLC | 23,032 | $32.0K | 0.00% | −18,868−45.0% | Reduced |
| Morgan Stanley | 23,174 | $31.0K | 0.00% | −37,486−61.8% | Reduced |
| Bailard, Inc. | 21,166 | $29.0K | 0.00% | +21,166 | New |
| Goldman Sachs Group Inc | 19,553 | $27.0K | 0.00% | −40,056−67.2% | Reduced |
| Northern Trust Corp | 14,067 | $19.0K | 0.00% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 11,805 | $16.0K | 0.00% | +11,805 | New |
| Barclays PLC | 11,442 | $15.0K | 0.00% | 00.0% | Unchanged |
| StoneX Group Inc. | 10,048 | $13.8K | 0.00% | −1,852−15.6% | Reduced |
| UBS Group AG | 7,512 | $10.0K | 0.00% | +1,664+28.5% | Added |
| Tower Research Capital LLC (TRC) | 7,325 | $10.0K | 0.00% | +4,302+142.3% | Added |
| Bank of America Corp | 1,317 | $2.00K | 0.00% | −1,532−53.8% | Reduced |
| Federated Hermes, Inc. | 1,125 | $2.00K | 0.00% | +137+13.9% | Added |
| Wells Fargo & Company | 664 | $1.00K | 0.00% | −395−37.3% | Reduced |
| FMR LLC | 416 | $1.00K | 0.00% | +1+0.2% | Added |
| Capital Advisors, Ltd. LLC | 634 | $1.00K | 0.00% | +515+432.8% | Added |
| JPMorgan Chase & Co | 11 | $0 | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 93 | $0 | 0.00% | −77−45.3% | Reduced |
| TCI Wealth Advisors, Inc. | 250 | $0 | 0.00% | 00.0% | Unchanged |
| Virtu Financial LLC | 0 | $0 | 0.00% | −15,738−100.0% | Sold out |
| Legal & General Group Plc | 0 | $0 | 0.00% | −782−100.0% | Sold out |
| Citigroup Inc | 0 | $0 | 0.00% | −393−100.0% | Sold out |
| New York State Common Retirement Fund | 0 | $0 | 0.00% | −77−100.0% | Sold out |
| Credit Suisse AG | 0 | $0 | 0.00% | −5−100.0% | Sold out |