Spruce Biosciences, Inc.
SPRB- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001683553
No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.
13F holders, Q3 2022
Institutional positions in Spruce Biosciences, Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 36
- −2 vs. Q2 2022
- Shares held
- 18.0M
- +1.67M (+10.2%) vs. Q2 2022
- Total value
- $24.7M
- −$3.75M (−13.2%) vs. Q2 2022
- New holders
- 3
- 7 more added
- Sold out
- 5
- 10 more reduced
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SPRB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 65 | $116.3M |
| Q1 2026 | 32 | $48.3M |
| Q4 2025 | 32 | $65.6M |
| Q3 2025 | 9 | $25.1M |
| Q2 2025 | 3 | $146.6K |
| Q1 2025 | 31 | $3.03M |
| Q4 2024 | 31 | $4.69M |
| Q3 2024 | 30 | $6.41M |
| Q2 2024 | 38 | $8.61M |
| Q1 2024 | 50 | $14.1M |
| Q4 2023 | 40 | $94.4M |
| Q3 2023 | 41 | $72.0M |
| Q2 2023 | 39 | $68.7M |
| Q1 2023 | 44 | $74.5M |
| Q4 2022 | 31 | $20.0M |
| Q3 2022 | 36 | $24.7M |
| Q2 2022 | 38 | $28.5M |
| Q1 2022 | 43 | $34.4M |
| Q4 2021 | 50 | $79.0M |
| Q3 2021 | 44 | $118.1M |
| Q2 2021 | 41 | $225.3M |
| Q1 2021 | 40 | $313.2M |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Spruce Biosciences, Inc.; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| JPMorgan Chase & Co | 11 | $0 | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 93 | $0 | 0.00% | −77−45.3% | Reduced |
| TCI Wealth Advisors, Inc. | 250 | $0 | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 664 | $1.00K | 0.00% | −395−37.3% | Reduced |
| FMR LLC | 416 | $1.00K | 0.00% | +1+0.2% | Added |
| Capital Advisors, Ltd. LLC | 634 | $1.00K | 0.00% | +515+432.8% | Added |
| Bank of America Corp | 1,317 | $2.00K | 0.00% | −1,532−53.8% | Reduced |
| Federated Hermes, Inc. | 1,125 | $2.00K | 0.00% | +137+13.9% | Added |
| UBS Group AG | 7,512 | $10.0K | 0.00% | +1,664+28.5% | Added |
| Tower Research Capital LLC (TRC) | 7,325 | $10.0K | 0.00% | +4,302+142.3% | Added |
| StoneX Group Inc. | 10,048 | $13.8K | 0.00% | −1,852−15.6% | Reduced |
| Barclays PLC | 11,442 | $15.0K | 0.00% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 11,805 | $16.0K | 0.00% | +11,805 | New |
| Northern Trust Corp | 14,067 | $19.0K | 0.00% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 19,553 | $27.0K | 0.00% | −40,056−67.2% | Reduced |
| Bailard, Inc. | 21,166 | $29.0K | 0.00% | +21,166 | New |
| Morgan Stanley | 23,174 | $31.0K | 0.00% | −37,486−61.8% | Reduced |
| Ergoteles LLC | 23,032 | $32.0K | 0.00% | −18,868−45.0% | Reduced |
| Bridgeway Capital Management, LLC | 60,000 | $82.0K | 0.00% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 60,755 | $83.0K | 0.00% | 00.0% | Unchanged |
| Marquette Asset Management, LLC | 64,090 | $88.0K | 0.03% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 92,764 | $127.0K | 0.00% | 00.0% | Unchanged |
| State Street Corp | 93,100 | $128.0K | 0.00% | 00.0% | Unchanged |
| Vanguard Group Inc | 124,979 | $171.0K | 0.00% | +8,921+7.7% | Added |
| Renaissance Technologies LLC | 143,100 | $196.0K | 0.00% | −8,300−5.5% | Reduced |
| Millennium Management LLC | 145,015 | $199.0K | 0.00% | −45,132−23.7% | Reduced |
| BlackRock Inc. | 149,823 | $205.0K | 0.00% | −6,216−4.0% | Reduced |
| Sands Capital Ventures, LLC | 787,007 | $1.08M | 0.31% | 00.0% | Unchanged |
| Logos Global Management LP | 1,000,000 | $1.37M | 0.17% | 00.0% | Unchanged |
| Aisling Capital Management LP | 1,205,511 | $1.65M | 1.10% | 00.0% | Unchanged |
| Rock Springs Capital Management LP | 1,622,689 | $2.22M | 0.06% | 00.0% | Unchanged |
| Citadel Advisors LLC | 1,729,543 | $2.37M | 0.00% | +5,090+0.3% | Added |
| Abingworth LLP | 1,792,518 | $2.47M | 0.85% | +1,792,518 | New |
| RiverVest Venture Management LLC | 2,148,281 | $2.94M | 3.42% | 00.0% | Unchanged |
| Omega Fund Management, LLC | 2,161,022 | $2.96M | 1.08% | 00.0% | Unchanged |
| Novo Holdings A/S | 4,514,336 | $6.18M | 0.30% | 00.0% | Unchanged |
| Virtu Financial LLC | 0 | $0 | 0.00% | −15,738−100.0% | Sold out |
| Legal & General Group Plc | 0 | $0 | 0.00% | −782−100.0% | Sold out |
| Citigroup Inc | 0 | $0 | 0.00% | −393−100.0% | Sold out |
| New York State Common Retirement Fund | 0 | $0 | 0.00% | −77−100.0% | Sold out |
| Credit Suisse AG | 0 | $0 | 0.00% | −5−100.0% | Sold out |