Spruce Biosciences, Inc.
SPRB- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001683553
No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Spruce Biosciences, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 31
- −5 vs. Q3 2022
- Shares held
- 18.2M
- +192.2K (+1.1%) vs. Q3 2022
- Total value
- $20.0M
- −$4.76M (−19.2%) vs. Q3 2022
- New holders
- 2
- 7 more added
- Sold out
- 7
- 9 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SPRB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 65 | $116.3M |
| Q1 2026 | 32 | $48.3M |
| Q4 2025 | 32 | $65.6M |
| Q3 2025 | 9 | $25.1M |
| Q2 2025 | 3 | $146.6K |
| Q1 2025 | 31 | $3.03M |
| Q4 2024 | 31 | $4.69M |
| Q3 2024 | 30 | $6.41M |
| Q2 2024 | 38 | $8.61M |
| Q1 2024 | 50 | $14.1M |
| Q4 2023 | 40 | $94.4M |
| Q3 2023 | 41 | $72.0M |
| Q2 2023 | 39 | $68.7M |
| Q1 2023 | 44 | $74.5M |
| Q4 2022 | 31 | $20.0M |
| Q3 2022 | 36 | $24.7M |
| Q2 2022 | 38 | $28.5M |
| Q1 2022 | 43 | $34.4M |
| Q4 2021 | 50 | $79.0M |
| Q3 2021 | 44 | $118.1M |
| Q2 2021 | 41 | $225.3M |
| Q1 2021 | 40 | $313.2M |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Spruce Biosciences, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Novo Holdings A/S | 4,514,336 | $4.95M | 0.31% | 00.0% | Unchanged |
| RiverVest Venture Management LLC | 2,148,281 | $2.36M | 2.75% | 00.0% | Unchanged |
| Omega Fund Management, LLC | 2,161,022 | $2.33M | 0.79% | 00.0% | Unchanged |
| Abingworth LLP | 1,792,518 | $1.97M | 0.65% | 00.0% | Unchanged |
| Citadel Advisors LLC | 1,747,391 | $1.92M | 0.00% | +17,848+1.0% | Added |
| Rock Springs Capital Management LP | 1,622,689 | $1.78M | 0.04% | 00.0% | Unchanged |
| Aisling Capital Management LP | 1,205,511 | $1.32M | 0.87% | 00.0% | Unchanged |
| Logos Global Management LP | 1,000,000 | $1.10M | 0.13% | 00.0% | Unchanged |
| Sands Capital Ventures, LLC | 787,007 | $866.0K | 0.24% | 00.0% | Unchanged |
| BML Capital Management, LLC | 221,830 | $243.4K | 0.23% | +221,830 | New |
| BlackRock Inc. | 150,419 | $165.1K | 0.00% | +596+0.4% | Added |
| Millennium Management LLC | 147,496 | $162.0K | 0.00% | +2,481+1.7% | Added |
| Renaissance Technologies LLC | 138,417 | $152.0K | 0.00% | −4,683−3.3% | Reduced |
| Vanguard Group Inc | 125,113 | $137.3K | 0.00% | +134+0.1% | Added |
| State Street Corp | 93,100 | $102.4K | 0.00% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 92,077 | $101.0K | 0.00% | −687−0.7% | Reduced |
| Marquette Asset Management, LLC | 68,357 | $75.0K | 0.02% | +4,267+6.7% | Added |
| Geode Capital Management, LLC | 60,621 | $66.0K | 0.00% | −134−0.2% | Reduced |
| Bridgeway Capital Management, LLC | 60,000 | $66.0K | 0.00% | 00.0% | Unchanged |
| Privium Fund Management (UK) Ltd | 50,400 | $55.3K | 0.04% | +50,400 | New |
| Northern Trust Corp | 14,067 | $15.4K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 10,926 | $12.0K | 0.00% | +3,601+49.2% | Added |
| Dimensional Fund Advisors LP | 10,261 | $11.0K | 0.00% | −1,544−13.1% | Reduced |
| Barclays PLC | 7,636 | $8.38K | 0.00% | −3,806−33.3% | Reduced |
| UBS Group AG | 5,644 | $6.21K | 0.00% | −1,868−24.9% | Reduced |
| Morgan Stanley | 3,339 | $3.66K | 0.00% | −19,835−85.6% | Reduced |
| Federated Hermes, Inc. | 1,206 | $1.32K | 0.00% | +81+7.2% | Added |
| Wells Fargo & Company | 466 | $511 | 0.00% | −198−29.8% | Reduced |
| TCI Wealth Advisors, Inc. | 250 | $274 | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 11 | $12 | 0.00% | −1,306−99.2% | Reduced |
| JPMorgan Chase & Co | 11 | $0 | 0.00% | 00.0% | Unchanged |
| Ergoteles LLC | 0 | $0 | 0.00% | −23,032−100.0% | Sold out |
| Bailard, Inc. | 0 | $0 | 0.00% | −21,166−100.0% | Sold out |
| Goldman Sachs Group Inc | 0 | $0 | 0.00% | −19,553−100.0% | Sold out |
| StoneX Group Inc. | 0 | $0 | 0.00% | −10,048−100.0% | Sold out |
| FMR LLC | 0 | $0 | 0.00% | −416−100.0% | Sold out |
| Capital Advisors, Ltd. LLC | 0 | $0 | 0.00% | −634−100.0% | Sold out |
| Royal Bank of Canada | 0 | $0 | 0.00% | −93−100.0% | Sold out |