Spruce Biosciences, Inc.
SPRB- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001683553
No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.
13F holders, Q2 2024
Institutional positions in Spruce Biosciences, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 38
- −12 vs. Q1 2024
- Shares held
- 16.6M
- −1.38M (−7.7%) vs. Q1 2024
- Total value
- $8.61M
- −$5.51M (−39.0%) vs. Q1 2024
- New holders
- 5
- 7 more added
- Sold out
- 17
- 14 more reduced
Compare with Q1 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SPRB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 65 | $116.3M |
| Q1 2026 | 32 | $48.3M |
| Q4 2025 | 32 | $65.6M |
| Q3 2025 | 9 | $25.1M |
| Q2 2025 | 3 | $146.6K |
| Q1 2025 | 31 | $3.03M |
| Q4 2024 | 31 | $4.69M |
| Q3 2024 | 30 | $6.41M |
| Q2 2024 | 38 | $8.61M |
| Q1 2024 | 50 | $14.1M |
| Q4 2023 | 40 | $94.4M |
| Q3 2023 | 41 | $72.0M |
| Q2 2023 | 39 | $68.7M |
| Q1 2023 | 44 | $74.5M |
| Q4 2022 | 31 | $20.0M |
| Q3 2022 | 36 | $24.7M |
| Q2 2022 | 38 | $28.5M |
| Q1 2022 | 43 | $34.4M |
| Q4 2021 | 50 | $79.0M |
| Q3 2021 | 44 | $118.1M |
| Q2 2021 | 41 | $225.3M |
| Q1 2021 | 40 | $313.2M |
Institutions, Q2 2024
Shares, value and share of portfolio for each institution holding Spruce Biosciences, Inc.; share changes are against Q1 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Royal Bank of Canada | 216 | $0 | 0.00% | +216 | New |
| Qube Research & Technologies Ltd | 2 | $1 | 0.00% | −39,594−100.0% | Reduced |
| JPMorgan Chase & Co | 72 | $38 | 0.00% | +61+554.5% | Added |
| Bank of America Corp | 150 | $78 | 0.00% | −25,980−99.4% | Reduced |
| Caldwell Sutter Capital, Inc. | 1,000 | $518 | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 2,133 | $1.10K | 0.00% | −19,390−90.1% | Reduced |
| Group One Trading, L.P. | 3,839 | $1.99K | 0.00% | −100−2.5% | Reduced |
| Shay Capital LLC | 13,172 | $6.82K | 0.00% | +13,172 | New |
| Marex Group plc | 14,800 | $7.66K | 0.00% | +14,800 | New |
| Charles Schwab Investment Management Inc | 15,289 | $7.92K | 0.00% | 00.0% | Unchanged |
| Privium Fund Management (UK) Ltd | 24,554 | $12.9K | 0.01% | 00.0% | Unchanged |
| XTX Topco Ltd | 27,185 | $14.1K | 0.00% | −29,562−52.1% | Reduced |
| Two Sigma Investments, LP | 28,584 | $14.8K | 0.00% | −94,429−76.8% | Reduced |
| Jane Street Group, LLC | 30,848 | $16.0K | 0.00% | −47,696−60.7% | Reduced |
| Tower Research Capital LLC (TRC) | 33,087 | $17.1K | 0.00% | +21,660+189.6% | Added |
| Two Sigma Advisers, LP | 45,700 | $23.7K | 0.00% | −44,600−49.4% | Reduced |
| State Street Corp | 64,400 | $33.3K | 0.00% | 00.0% | Unchanged |
| Northern Trust Corp | 74,927 | $38.8K | 0.00% | −280.0% | Reduced |
| Lion Point Capital, LP | 75,000 | $38.8K | 0.12% | 00.0% | Unchanged |
| Superstring Capital Management LP | 77,992 | $40.4K | 0.05% | −362,233−82.3% | Reduced |
| Citadel Advisors LLC | 84,715 | $43.9K | 0.00% | −3,162−3.6% | Reduced |
| Bridgeway Capital Management, LLC | 85,000 | $44.0K | 0.00% | 00.0% | Unchanged |
| BlackRock Inc. | 124,734 | $64.6K | 0.00% | −61,214−32.9% | Reduced |
| UBS Group AG | 131,923 | $68.3K | 0.00% | +116,109+734.2% | Added |
| 683 Capital Management, LLC | 140,934 | $73.0K | 0.01% | +140,934 | New |
| Geode Capital Management, LLC | 204,002 | $105.6K | 0.00% | +3,840+1.9% | Added |
| ADAR1 Capital Management, LLC | 355,216 | $183.9K | 0.04% | −10,000−2.7% | Reduced |
| Renaissance Technologies LLC | 366,100 | $189.5K | 0.00% | +95,100+35.1% | Added |
| ExodusPoint Capital Management, LP | 386,702 | $200.0K | 0.00% | +161,869+72.0% | Added |
| Almitas Capital LLC | 396,506 | $205.3K | 0.09% | +396,506 | New |
| Sands Capital Ventures, LLC | 787,007 | $409.2K | 0.14% | 00.0% | Unchanged |
| Altium Capital Management LP | 811,167 | $419.9K | 0.17% | −338,833−29.5% | Reduced |
| Vanguard Group Inc | 863,375 | $447.0K | 0.00% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 1,367,997 | $707.0K | 0.00% | +999,166+270.9% | Added |
| Rosalind Advisors, Inc. | 1,508,419 | $780.9K | 0.62% | 00.0% | Unchanged |
| Rock Springs Capital Management LP | 2,609,125 | $1.35M | 0.04% | 00.0% | Unchanged |
| Carlyle Group Inc. | 2,896,518 | $1.52M | 0.14% | 00.0% | Unchanged |
| RiverVest Venture Management LLC | 2,936,281 | $1.52M | 22.27% | 00.0% | Unchanged |
| Aisling Capital Management LP | 0 | $0 | 0.00% | −1,205,511−100.0% | Sold out |
| Panagora Asset Management Inc | 0 | $0 | 0.00% | −253,682−100.0% | Sold out |
| AWM Investment Company, Inc. | 0 | $0 | 0.00% | −200,000−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −178,958−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −102,223−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −72,245−100.0% | Sold out |
| Castleview Partners, LLC | 0 | $0 | 0.00% | −59,709−100.0% | Sold out |
| Dimensional Fund Advisors LP | 0 | $0 | 0.00% | −46,664−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −29,709−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −28,100−100.0% | Sold out |
| Two Sigma Securities, LLC | 0 | $0 | 0.00% | −26,016−100.0% | Sold out |
| Belvedere Trading LLC | 0 | $0 | 0.00% | −24,900−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −22,508−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −16,000−100.0% | Sold out |
| Wells Fargo & Company | 0 | $0 | 0.00% | −143−100.0% | Sold out |
| FMR LLC | 0 | $0 | 0.00% | −103−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −362−100.0% | Sold out |