Spruce Biosciences, Inc.
SPRB- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001683553
No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.
13F holders, Q2 2023
Institutional positions in Spruce Biosciences, Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 39
- −5 vs. Q1 2023
- Shares held
- 32.0M
- −1.79M (−5.3%) vs. Q1 2023
- Total value
- $68.7M
- −$5.80M (−7.8%) vs. Q1 2023
- New holders
- 4
- 11 more added
- Sold out
- 9
- 11 more reduced
Compare with Q1 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SPRB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 65 | $116.3M |
| Q1 2026 | 32 | $48.3M |
| Q4 2025 | 32 | $65.6M |
| Q3 2025 | 9 | $25.1M |
| Q2 2025 | 3 | $146.6K |
| Q1 2025 | 31 | $3.03M |
| Q4 2024 | 31 | $4.69M |
| Q3 2024 | 30 | $6.41M |
| Q2 2024 | 38 | $8.61M |
| Q1 2024 | 50 | $14.1M |
| Q4 2023 | 40 | $94.4M |
| Q3 2023 | 41 | $72.0M |
| Q2 2023 | 39 | $68.7M |
| Q1 2023 | 44 | $74.5M |
| Q4 2022 | 31 | $20.0M |
| Q3 2022 | 36 | $24.7M |
| Q2 2022 | 38 | $28.5M |
| Q1 2022 | 43 | $34.4M |
| Q4 2021 | 50 | $79.0M |
| Q3 2021 | 44 | $118.1M |
| Q2 2021 | 41 | $225.3M |
| Q1 2021 | 40 | $313.2M |
Institutions, Q2 2023
Shares, value and share of portfolio for each institution holding Spruce Biosciences, Inc.; share changes are against Q1 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| UBS Group AG | 13 | $28 | 0.00% | −947−98.6% | Reduced |
| Wells Fargo & Company | 186 | $400 | 0.00% | +119+177.6% | Added |
| Caldwell Sutter Capital, Inc. | 1,000 | $2.15K | 0.00% | +1,000 | New |
| Morgan Stanley | 2,131 | $4.58K | 0.00% | −1,019−32.3% | Reduced |
| Royal Bank of Canada | 2,531 | $5.00K | 0.00% | −91,389−97.3% | Reduced |
| Tower Research Capital LLC (TRC) | 2,358 | $5.07K | 0.00% | −1,522−39.2% | Reduced |
| Charles Schwab Investment Management Inc | 15,289 | $32.9K | 0.00% | +15,289 | New |
| JPMorgan Chase & Co | 23,560 | $50.7K | 0.00% | −34,619−59.5% | Reduced |
| Privium Fund Management (UK) Ltd | 24,554 | $52.1K | 0.04% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 32,440 | $69.7K | 0.00% | −6,728−17.2% | Reduced |
| Marquette Asset Management, LLC | 55,757 | $119.9K | 0.03% | 00.0% | Unchanged |
| Northern Trust Corp | 57,097 | $122.8K | 0.00% | +43,356+315.5% | Added |
| Sofinnova Investments, Inc. | 58,029 | $124.8K | 0.01% | +58,029 | New |
| State Street Corp | 58,793 | $126.4K | 0.00% | −34,307−36.8% | Reduced |
| Citadel Advisors LLC | 71,277 | $153.2K | 0.00% | −1,627,341−95.8% | Reduced |
| Bridgeway Capital Management, LLC | 85,000 | $182.8K | 0.00% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 91,455 | $196.6K | 0.00% | −622−0.7% | Reduced |
| Geode Capital Management, LLC | 217,911 | $468.5K | 0.00% | +157,290+259.5% | Added |
| Two Sigma Investments, LP | 228,130 | $490.5K | 0.00% | +64,965+39.8% | Added |
| Renaissance Technologies LLC | 239,099 | $514.0K | 0.00% | +78,999+49.3% | Added |
| Two Sigma Advisers, LP | 240,000 | $516.0K | 0.00% | +202,400+538.3% | Added |
| BlackRock Inc. | 260,979 | $561.1K | 0.00% | +109,666+72.5% | Added |
| Vanguard Group Inc | 261,954 | $563.2K | 0.00% | +15,376+6.2% | Added |
| Acuitas Investments, LLC | 275,006 | $591.3K | 0.34% | +275,006 | New |
| Worth Venture Partners, LLC | 277,624 | $596.9K | 0.33% | +7,000+2.6% | Added |
| DAFNA Capital Management LLC | 312,000 | $670.8K | 0.18% | 00.0% | Unchanged |
| Millennium Management LLC | 577,658 | $1.24M | 0.00% | −31,187−5.1% | Reduced |
| Sands Capital Ventures, LLC | 787,007 | $1.69M | 0.50% | 00.0% | Unchanged |
| Alyeska Investment Group, L.P. | 1,000,000 | $2.15M | 0.02% | 00.0% | Unchanged |
| Verition Fund Management LLC | 1,083,730 | $2.33M | 0.04% | +121,831+12.7% | Added |
| AIGH Capital Management LLC | 1,111,000 | $2.39M | 0.98% | +7,000+0.6% | Added |
| Aisling Capital Management LP | 1,205,511 | $2.59M | 1.27% | 00.0% | Unchanged |
| Omega Fund Management, LLC | 2,161,022 | $4.65M | 2.60% | 00.0% | Unchanged |
| 5AM Venture Management, LLC | 2,364,000 | $5.08M | 1.27% | 00.0% | Unchanged |
| Rock Springs Capital Management LP | 2,728,125 | $5.87M | 0.14% | 00.0% | Unchanged |
| Carlyle Group Inc. | 2,896,518 | $6.23M | 0.22% | 00.0% | Unchanged |
| RiverVest Venture Management LLC | 2,936,281 | $6.31M | 7.00% | 00.0% | Unchanged |
| Armistice Capital, LLC | 3,498,000 | $7.52M | 0.19% | −430,000−10.9% | Reduced |
| Novo Holdings A/S | 6,722,336 | $14.5M | 1.12% | 00.0% | Unchanged |
| CVI Holdings, LLC | 0 | $0 | 0.00% | −472,000−100.0% | Sold out |
| Goldman Sachs Group Inc | 0 | $0 | 0.00% | −182,656−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −13,722−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −13,340−100.0% | Sold out |
| Barclays PLC | 0 | $0 | 0.00% | −7,484−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −1,032−100.0% | Sold out |
| TCI Wealth Advisors, Inc. | 0 | $0 | 0.00% | −250−100.0% | Sold out |
| Bank of America Corp | 0 | $0 | 0.00% | −249−100.0% | Sold out |
| FMR LLC | 0 | $0 | 0.00% | −50−100.0% | Sold out |