Spruce Biosciences, Inc.
SPRB- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001683553
No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.
13F holders, Q2 2021
Institutional positions in Spruce Biosciences, Inc. as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 41
- +1 vs. Q1 2021
- Shares held
- 20.1M
- +1.23M (+6.5%) vs. Q1 2021
- Total value
- $225.3M
- −$87.9M (−28.1%) vs. Q1 2021
- New holders
- 5
- 17 more added
- Sold out
- 4
- 12 more reduced
Compare with Q1 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SPRB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 65 | $116.3M |
| Q1 2026 | 32 | $48.3M |
| Q4 2025 | 32 | $65.6M |
| Q3 2025 | 9 | $25.1M |
| Q2 2025 | 3 | $146.6K |
| Q1 2025 | 31 | $3.03M |
| Q4 2024 | 31 | $4.69M |
| Q3 2024 | 30 | $6.41M |
| Q2 2024 | 38 | $8.61M |
| Q1 2024 | 50 | $14.1M |
| Q4 2023 | 40 | $94.4M |
| Q3 2023 | 41 | $72.0M |
| Q2 2023 | 39 | $68.7M |
| Q1 2023 | 44 | $74.5M |
| Q4 2022 | 31 | $20.0M |
| Q3 2022 | 36 | $24.7M |
| Q2 2022 | 38 | $28.5M |
| Q1 2022 | 43 | $34.4M |
| Q4 2021 | 50 | $79.0M |
| Q3 2021 | 44 | $118.1M |
| Q2 2021 | 41 | $225.3M |
| Q1 2021 | 40 | $313.2M |
Institutions, Q2 2021
Shares, value and share of portfolio for each institution holding Spruce Biosciences, Inc.; share changes are against Q1 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Citigroup Inc | 414 | $5.00K | 0.00% | −48−10.4% | Reduced |
| Royal Bank of Canada | 595 | $7.00K | 0.00% | −202−25.3% | Reduced |
| Ameritas Investment Partners, Inc. | 584 | $7.00K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 782 | $9.00K | 0.00% | +75+10.6% | Added |
| Tower Research Capital LLC (TRC) | 933 | $10.0K | 0.00% | +248+36.2% | Added |
| STRS Ohio | 2,400 | $26.0K | 0.00% | 00.0% | Unchanged |
| American International Group, Inc. | 4,866 | $55.0K | 0.00% | +806+19.9% | Added |
| Deutsche Bank AG | 5,185 | $58.0K | 0.00% | +726+16.3% | Added |
| New York State Common Retirement Fund | 6,059 | $68.0K | 0.00% | +59+1.0% | Added |
| Wells Fargo & Company | 7,034 | $79.0K | 0.00% | +4,860+223.6% | Added |
| Bank of America Corp | 7,853 | $88.0K | 0.00% | −5,024−39.0% | Reduced |
| Goldman Sachs Group Inc | 10,770 | $121.0K | 0.00% | −1,677−13.5% | Reduced |
| Two Sigma Investments, LP | 11,975 | $134.0K | 0.00% | +11,975 | New |
| California State Teachers Retirement System | 12,006 | $135.0K | 0.00% | +1,470+14.0% | Added |
| Laurion Capital Management LP | 14,957 | $168.0K | 0.00% | −5,043−25.2% | Reduced |
| Millennium Management LLC | 17,216 | $193.0K | 0.00% | −55,865−76.4% | Reduced |
| Alyeska Investment Group, L.P. | 19,413 | $218.0K | 0.00% | +19,413 | New |
| Bank of New York Mellon Corp | 25,566 | $286.0K | 0.00% | +6,386+33.3% | Added |
| Nuveen Asset Management, LLC | 29,616 | $332.0K | 0.00% | +18,194+159.3% | Added |
| Alps Advisors Inc | 30,726 | $344.0K | 0.00% | +30,726 | New |
| Charles Schwab Investment Management Inc | 43,229 | $485.0K | 0.00% | −909−2.1% | Reduced |
| Northern Trust Corp | 77,864 | $873.0K | 0.00% | +1,720+2.3% | Added |
| Caas Capital Management LP | 92,412 | $1.04M | 0.06% | +92,412 | New |
| Granite Point Capital Management, L.P. | 100,000 | $1.12M | 0.33% | 00.0% | Unchanged |
| Morgan Stanley | 122,590 | $1.38M | 0.00% | +88,298+257.5% | Added |
| State Street Corp | 124,918 | $1.40M | 0.00% | +30,169+31.8% | Added |
| Geode Capital Management, LLC | 128,546 | $1.44M | 0.00% | +18,999+17.3% | Added |
| JPMorgan Chase & Co | 163,857 | $1.84M | 0.00% | −16,166−9.0% | Reduced |
| Adage Capital Partners GP, L.L.C. | 240,511 | $2.70M | 0.01% | −50,000−17.2% | Reduced |
| Vanguard Group Inc | 369,520 | $4.14M | 0.00% | +181,003+96.0% | Added |
| BlackRock Inc. | 419,789 | $4.71M | 0.00% | +74,483+21.6% | Added |
| Sio Capital Management, LLC | 647,239 | $7.26M | 1.97% | −165,645−20.4% | Reduced |
| Sands Capital Management, LLC | 787,007 | $8.82M | 0.01% | 00.0% | Unchanged |
| FMR LLC | 1,185,673 | $13.3M | 0.00% | −9,417−0.8% | Reduced |
| Aisling Capital Management LP | 1,205,511 | $13.5M | 2.16% | 00.0% | Unchanged |
| Rock Springs Capital Management LP | 1,605,001 | $18.0M | 0.36% | +25,700+1.6% | Added |
| Citadel Advisors LLC | 1,703,014 | $19.1M | 0.02% | +2090.0% | Added |
| Deerfield Management Company, L.P. (Series C) | 2,046,958 | $22.9M | 0.41% | +2,046,958 | New |
| RiverVest Venture Management LLC | 2,148,281 | $24.1M | 4.71% | 00.0% | Unchanged |
| Omega Fund Management, LLC | 2,161,022 | $24.2M | 2.74% | 00.0% | Unchanged |
| Novo Holdings A/S | 4,514,336 | $50.6M | 2.24% | −475,000−9.5% | Reduced |
| PFM Health Sciences, LP | 0 | $0 | 0.00% | −489,631−100.0% | Sold out |
| ArrowMark Colorado Holdings LLC | 0 | $0 | 0.00% | −128,000−100.0% | Sold out |
| Credit Suisse AG | 0 | $0 | 0.00% | −23,899−100.0% | Sold out |
| Bank of Montreal | 0 | $0 | 0.00% | −216−100.0% | Sold out |