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Spruce Biosciences, Inc.

SPRB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001683553

No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.

13F holders, Q1 2021

Institutional positions in Spruce Biosciences, Inc. as of Mar 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
40
No complete 13F data for Q4 2020
Shares held
18.9M
No complete 13F data for Q4 2020
Total value
$313.2M
No complete 13F data for Q4 2020

Holders and value by quarter

Institutions reporting SPRB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2021: 40 institutions
Q1 2021: 40 institutionsQ2 2021: 41 institutionsQ3 2021: 44 institutionsQ4 2021: 50 institutionsQ1 2022: 43 institutionsQ2 2022: 38 institutionsQ3 2022: 36 institutionsQ4 2022: 31 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 41 institutionsQ4 2023: 40 institutionsQ1 2024: 50 institutionsQ2 2024: 38 institutionsQ3 2024: 30 institutionsQ4 2024: 31 institutionsQ1 2025: 31 institutionsQ2 2025: 3 institutionsQ3 2025: 9 institutionsQ4 2025: 32 institutionsQ1 2026: 32 institutionsQ2 2026: 65 institutions
Value heldQ1 2021: $313.2M
Q1 2021: $313.2MQ2 2021: $225.3MQ3 2021: $118.1MQ4 2021: $79.0MQ1 2022: $34.4MQ2 2022: $28.5MQ3 2022: $24.7MQ4 2022: $20.0MQ1 2023: $74.5MQ2 2023: $68.7MQ3 2023: $72.0MQ4 2023: $94.4MQ1 2024: $14.1MQ2 2024: $8.61MQ3 2024: $6.41MQ4 2024: $4.69MQ1 2025: $3.03MQ2 2025: $146.6KQ3 2025: $25.1MQ4 2025: $65.6MQ1 2026: $48.3MQ2 2026: $116.3M
Institutions holding SPRB and their total value by quarter
QuarterHoldersValue
Q2 202665$116.3M
Q1 202632$48.3M
Q4 202532$65.6M
Q3 20259$25.1M
Q2 20253$146.6K
Q1 202531$3.03M
Q4 202431$4.69M
Q3 202430$6.41M
Q2 202438$8.61M
Q1 202450$14.1M
Q4 202340$94.4M
Q3 202341$72.0M
Q2 202339$68.7M
Q1 202344$74.5M
Q4 202231$20.0M
Q3 202236$24.7M
Q2 202238$28.5M
Q1 202243$34.4M
Q4 202150$79.0M
Q3 202144$118.1M
Q2 202141$225.3M
Q1 202140$313.2M

Institutions, Q1 2021

Shares, value and share of portfolio for each institution holding Spruce Biosciences, Inc..

Livermore's 13F data starts with Q1 2021, so Q1 2021 has no change from the previous quarter.

Institutions holding SPRB in Q1 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Bank of Montreal216$3.00K0.00%––
Citigroup Inc462$8.00K0.00%––
Ameritas Investment Partners, Inc.584$10.0K0.00%––
Tower Research Capital LLC (TRC)685$11.0K0.00%––
Legal & General Group Plc707$12.0K0.00%––
Royal Bank of Canada797$13.0K0.00%––
Wells Fargo & Company2,174$36.0K0.00%––
STRS Ohio2,400$39.0K0.00%––
American International Group, Inc.4,060$67.0K0.00%––
Deutsche Bank AG4,459$74.0K0.00%––
New York State Common Retirement Fund6,000$100.0K0.00%––
California State Teachers Retirement System10,536$175.0K0.00%––
Nuveen Asset Management, LLC11,422$190.0K0.00%––
Goldman Sachs Group Inc12,447$207.0K0.00%––
Bank of America Corp12,877$214.0K0.00%––
Bank of New York Mellon Corp19,180$318.0K0.00%––
Laurion Capital Management LP20,000$332.0K0.00%––
Credit Suisse AG23,899$397.0K0.00%––
Morgan Stanley34,292$569.0K0.00%––
Charles Schwab Investment Management Inc44,138$733.0K0.00%––
Millennium Management LLC73,081$1.21M0.00%––
Northern Trust Corp76,144$1.26M0.00%––
State Street Corp94,749$1.57M0.00%––
Granite Point Capital Management, L.P.100,000$1.66M0.49%––
Geode Capital Management, LLC109,547$1.82M0.00%––
ArrowMark Colorado Holdings LLC128,000$2.13M0.02%––
JPMorgan Chase & Co180,023$2.99M0.00%––
Vanguard Group Inc188,517$3.13M0.00%––
Adage Capital Partners GP, L.L.C.290,511$4.82M0.01%––
BlackRock Inc.345,306$5.73M0.00%––
PFM Health Sciences, LP489,631$8.13M0.28%––
Sands Capital Management, LLC787,007$13.1M0.03%––
Sio Capital Management, LLC812,884$13.5M2.82%––
FMR LLC1,195,090$19.8M0.00%––
Aisling Capital Management LP1,205,511$20.0M3.60%––
Rock Springs Capital Management LP1,579,301$26.2M0.57%––
Citadel Advisors LLC1,702,805$28.3M0.03%––
RiverVest Venture Management LLC2,148,281$35.7M5.49%––
Omega Fund Management, LLC2,161,022$35.9M3.39%––
Novo Holdings A/S4,989,336$82.8M3.42%––