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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2026

Institutional positions in Rhythm Pharmaceuticals, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
304
+23 vs. Q1 2026
Shares held
77.2M
+4.58M (+6.3%) vs. Q1 2026
Total value
$8.55B
+$2.21B (+34.8%) vs. Q1 2026
New holders
64
105 more added
Sold out
41
101 more reduced

4 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 304 institutions
Q1 2021: 124 institutionsQ2 2021: 105 institutionsQ3 2021: 97 institutionsQ4 2021: 98 institutionsQ1 2022: 111 institutionsQ2 2022: 90 institutionsQ3 2022: 101 institutionsQ4 2022: 115 institutionsQ1 2023: 126 institutionsQ2 2023: 116 institutionsQ3 2023: 144 institutionsQ4 2023: 169 institutionsQ1 2024: 167 institutionsQ2 2024: 165 institutionsQ3 2024: 176 institutionsQ4 2024: 203 institutionsQ1 2025: 228 institutionsQ2 2025: 227 institutionsQ3 2025: 264 institutionsQ4 2025: 281 institutionsQ1 2026: 285 institutionsQ2 2026: 304 institutions
Value heldQ2 2026: $8.55B
Q1 2021: $1.01BQ2 2021: $905.6MQ3 2021: $626.3MQ4 2021: $483.6MQ1 2022: $562.7MQ2 2022: $190.8MQ3 2022: $1.45BQ4 2022: $1.81BQ1 2023: $1.08BQ2 2023: $1.09BQ3 2023: $1.56BQ4 2023: $3.07BQ1 2024: $2.95BQ2 2024: $2.85BQ3 2024: $3.55BQ4 2024: $3.63BQ1 2025: $3.44BQ2 2025: $4.20BQ3 2025: $7.20BQ4 2025: $7.80BQ1 2026: $6.42BQ2 2026: $8.55B
Institutions holding RYTM and their total value by quarter
QuarterHoldersValue
Q2 2026304$8.55B
Q1 2026285$6.42B
Q4 2025281$7.80B
Q3 2025264$7.20B
Q2 2025227$4.20B
Q1 2025228$3.44B
Q4 2024203$3.63B
Q3 2024176$3.55B
Q2 2024165$2.85B
Q1 2024167$2.95B
Q4 2023169$3.07B
Q3 2023144$1.56B
Q2 2023116$1.09B
Q1 2023126$1.08B
Q4 2022115$1.81B
Q3 2022101$1.45B
Q2 202290$190.8M
Q1 2022111$562.7M
Q4 202198$483.6M
Q3 202197$626.3M
Q2 2021105$905.6M
Q1 2021124$1.01B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q1 2026.

Institutions holding RYTM in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Sound View Wealth Advisors Group, LLC3,682$408.8K0.03%+3,682New
Freestone Capital Holdings, LLC3,700$410.8K0.01%00.0%Unchanged
Virginia Retirement Systems Et Al3,700$410.8K0.00%+3,700New
Ensign Peak Advisors, Inc3,709$411.8K0.00%−150−3.9%Reduced
Envestnet Asset Management Inc3,769$418.5K0.00%+3,769New
Quantinno Capital Management LP3,838$426.1K0.00%−13−0.3%Reduced
Mitsubishi UFJ Trust & Banking Corp3,860$428.6K0.00%+3,860New
Magnetar Financial LLC3,908$433.9K0.00%+3,908New
Matisse Capital4,000$444.1K0.18%+4,000New
JustInvest LLC4,054$450.1K0.00%+952+30.7%Added
O'Shaughnessy Asset Management, LLC4,122$457.7K0.00%+4,122New
Principal Financial Group Inc4,220$468.5K0.00%−1,417−25.1%Reduced
Abel Hall, LLC4,258$472.8K0.08%+243+6.1%Added
Fifth Third Bancorp4,290$476.4K0.00%−970−18.4%Reduced
Susquehanna International Group, LLP4,372$485.4K0.00%−46,412−91.4%Reduced
Two Sigma Investments, LP4,600$510.7K0.00%+300+7.0%Added
E Fund Management Co., Ltd.4,751$527.5K0.01%−1,702−26.4%Reduced
Allstate Corp4,925$546.8K0.01%+4,925New
Fulcrum Asset Management LLP5,049$555.6K0.06%+5,049New
Ameritas Investment Partners, Inc.5,010$556.3K0.01%+645+14.8%Added
Nelson, Van Denburg & Campbell Wealth Management Group, LLC5,440$604.0K0.02%+790+17.0%Added
Xponance, Inc.5,465$606.8K0.00%+475+9.5%Added
Public Employees Retirement Association of Colorado5,463$607.0K0.00%00.0%Unchanged
Gotham Asset Management, LLC5,516$612.4K0.00%+668+13.8%Added
E. Ohman J:or Asset Management AB5,523$613.2K0.01%+1,114+25.3%Added
Teachers Retirement System of the State of Kentucky5,601$622.0K0.00%+5,601New
Great West Life Assurance Co5,797$642.0K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.5,945$660.1K0.00%+1,101+22.7%Added
Walleye Capital LLC5,996$665.7K0.00%+5,996New
STRS Ohio6,000$666.2K0.00%−22,914−79.2%Reduced
LPL Financial LLC6,284$697.7K0.00%+86+1.4%Added
State of Wyoming6,354$705.5K0.07%+6,354New
Teacher Retirement System of Texas6,370$707.3K0.00%−960−13.1%Reduced
Pathstone Holdings, LLC6,911$767.3K0.00%+6,911New
The PNC Financial Services Group, Inc.7,657$850.2K0.00%+719+10.4%Added
Victory Capital Management Inc7,679$852.6K0.00%−12,825−62.5%Reduced
Toth Financial Advisory Corp7,800$866.0K0.08%−2,200−22.0%Reduced
Y-Intercept (Hong Kong) Ltd7,925$879.9K0.02%+7,925New
Exchange Traded Concepts, LLC7,966$884.5K0.00%−497−5.9%Reduced
Marshall Wace, LLP8,174$907.6K0.00%−1,454−15.1%Reduced
Inceptionr LLC9,353$1.04M0.26%+4,974+113.6%Added
Universal- Beteiligungs- und Servicegesellschaft mbH9,393$1.04M0.00%−53,543−85.1%Reduced
AlphaCentric Advisors LLC9,449$1.05M0.89%+152+1.6%Added
ProShare Advisors LLC9,476$1.05M0.00%−1,244−11.6%Reduced
Cannon Financial Strategists, Inc.10,000$1.11M0.13%00.0%Unchanged
China Universal Asset Management Co., Ltd.10,917$1.21M0.07%−1,201−9.9%Reduced
Mackenzie Financial Corp10,936$1.21M0.00%+10,936New
Guggenheim Capital LLC10,984$1.22M0.01%−5,570−33.6%Reduced
Susquehanna Portfolio Strategies, LLC11,073$1.23M0.02%+11,073New
Bridgefront Capital, LLC11,282$1.25M0.33%−1,213−9.7%Reduced
DnB Asset Management AS11,465$1.27M0.00%+270+2.4%Added
Intech Investment Management LLC11,664$1.30M0.01%−2,075−15.1%Reduced
Jones Financial Companies LLLP12,066$1.33M0.00%+7,148+145.3%Added
Entropy Technologies, LP12,077$1.34M0.05%+1,759+17.0%Added
KLP Kapitalforvaltning AS12,500$1.39M0.00%00.0%Unchanged
Stifel Financial Corp12,689$1.41M0.00%+350+2.8%Added
Virtus Investment Advisers, Inc.13,158$1.46M0.34%+5,724+77.0%Added
Barclays PLC13,209$1.47M0.00%+2,557+24.0%Added
HighVista Strategies LLC13,657$1.52M0.35%−3,139−18.7%Reduced
Jasper Ridge Partners, L.P.13,845$1.54M0.03%00.0%Unchanged
Tudor Investment Corp Et Al13,886$1.54M0.01%−5,760−29.3%Reduced
Natixis Advisors, L.P.14,483$1.61M0.00%+14,483New
Vanguard Investments Australia, Ltd.14,666$1.63M0.00%+739+5.3%Added
Arizona State Retirement System15,073$1.67M0.01%−508−3.3%Reduced
State Board of Administration of Florida Retirement System15,342$1.70M0.00%+692+4.7%Added
Los Angeles Capital Management LLC15,641$1.74M0.01%+6,422+69.7%Added
Police & Firemen's Retirement System of New Jersey16,280$1.81M0.01%+1,686+11.6%Added
Profund Advisors LLC16,805$1.87M0.05%−5,982−26.3%Reduced
State of New Jersey Common Pension Fund D17,664$1.96M0.01%−1,722−8.9%Reduced
Knights of Columbus Asset Advisors LLC18,043$2.00M0.10%+2,454+15.7%Added
Lazard Asset Management LLC18,319$2.03M0.00%−14,569−44.3%Reduced
Handelsbanken Fonder AB18,921$2.10M0.01%+1,400+8.0%Added
Dimensional Fund Advisors LP18,973$2.11M0.00%−178−0.9%Reduced
Legato Capital Management LLC19,024$2.11M0.18%+19,024New
Aquatic Capital Management LLC19,754$2.19M0.08%−9,917−33.4%Reduced
Captrust Financial Advisors19,945$2.21M0.00%+1,798+9.9%Added
SG Americas Securities, LLC21,333$2.37M0.00%+2,573+13.7%Added
Advisors Asset Management, Inc.21,896$2.43M0.04%+3,178+17.0%Added
SEI Investments Co22,087$2.45M0.00%−18,598−45.7%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)23,109$2.57M0.00%+7,511+48.2%Added
Wedge Capital Management L L P23,422$2.60M0.04%−1,113−4.5%Reduced
Vanguard Global Advisers, LLC23,654$2.63M0.00%−6,046−20.4%Reduced
Creative Planning25,835$2.87M0.00%+4,750+22.5%Added
Mutual of America Capital Management LLC27,861$3.09M0.03%+5,332+23.7%Added
Aspiriant, LLC27,960$3.10M0.08%−5,047−15.3%Reduced
Schonfeld Strategic Advisors LLC28,607$3.18M0.02%+28,607New
Mirae Asset Global ETFs Holdings Ltd.29,159$3.23M0.00%−5,518−15.9%Reduced
D. E. Shaw & Co., Inc.30,168$3.35M0.00%−2,484−7.6%Reduced
MetLife Investment Management32,104$3.56M0.02%+3,215+11.1%Added
State of Wisconsin Investment Board32,189$3.57M0.01%−4,382−12.0%Reduced
Rafferty Asset Management, LLC32,207$3.58M0.01%−17,898−35.7%Reduced
Exome Asset Management LLC32,209$3.58M2.21%−8,372−20.6%Reduced
First Trust Advisors LP32,482$3.61M0.00%−53,024−62.0%Reduced
EFG International AG33,577$3.73M0.07%−637−1.9%Reduced
TD Asset Management Inc38,778$4.31M0.00%00.0%Unchanged
BNP PARIBAS ASSET MANAGEMENT Holding S.A.41,929$4.66M0.00%−1,943−4.4%Reduced
Zweig-DiMenna Associates LLC42,100$4.67M0.42%+42,100New
Cinctive Capital Management LP42,739$4.75M0.19%+42,739New
Legal & General Group Plc43,908$4.88M0.00%−3,124−6.6%Reduced
Hillsdale Investment Management Inc.44,000$4.89M0.11%+3,700+9.2%Added