Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 305 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2025
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 227
- 0 vs. Q1 2025
- Shares held
- 66.5M
- +1.72M (+2.7%) vs. Q1 2025
- Total value
- $4.20B
- +$767.9M (+22.3%) vs. Q1 2025
- New holders
- 33
- 93 more added
- Sold out
- 33
- 74 more reduced
1 institution that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 305 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Citigroup Inc | 34,324 | $2.17M | 0.00% | −51,882−60.2% | Reduced |
| Alps Advisors Inc | 34,178 | $2.16M | 0.01% | −12,029−26.0% | Reduced |
| SEI Investments Co | 33,145 | $2.09M | 0.00% | +764+2.4% | Added |
| MetLife Investment Management | 32,395 | $2.05M | 0.01% | −19−0.1% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 32,351 | $2.04M | 0.00% | −2,931−8.3% | Reduced |
| State of New Jersey Common Pension Fund D | 30,373 | $1.92M | 0.01% | −5,019−14.2% | Reduced |
| Wedge Capital Management L L P | 29,991 | $1.90M | 0.03% | −6,993−18.9% | Reduced |
| HighVista Strategies LLC | 28,068 | $1.77M | 0.65% | −6,971−19.9% | Reduced |
| Intech Investment Management LLC | 27,443 | $1.73M | 0.02% | −6,450−19.0% | Reduced |
| SummitTX Capital, L.P. | 25,452 | $1.61M | 0.07% | +8,109+46.8% | Added |
| Readystate Asset Management LP | 24,666 | $1.56M | 0.06% | +24,666 | New |
| D. E. Shaw & Co., Inc. | 24,278 | $1.53M | 0.00% | −59,591−71.1% | Reduced |
| Wellington Management Group LLP | 22,425 | $1.42M | 0.00% | −1,133−4.8% | Reduced |
| Bellevue Group AG | 20,906 | $1.32M | 0.03% | +5,356+34.4% | Added |
| Stifel Financial Corp | 18,177 | $1.15M | 0.00% | −310−1.7% | Reduced |
| Engineers Gate Manager LP | 17,676 | $1.12M | 0.01% | −4,207−19.2% | Reduced |
| Jump Financial, LLC | 17,671 | $1.12M | 0.01% | −24,089−57.7% | Reduced |
| Ensign Peak Advisors, Inc | 17,659 | $1.12M | 0.00% | 00.0% | Unchanged |
| Schroder Investment Management Group | 17,618 | $1.11M | 0.00% | 00.0% | Unchanged |
| Captrust Financial Advisors | 17,471 | $1.10M | 0.00% | +114+0.7% | Added |
| STRS Ohio | 17,400 | $1.10M | 0.00% | −1,100−5.9% | Reduced |
| Creative Planning | 17,222 | $1.09M | 0.00% | +4,889+39.6% | Added |
| Victory Capital Management Inc | 16,241 | $1.03M | 0.00% | −1,085−6.3% | Reduced |
| Handelsbanken Fonder AB | 15,521 | $981.0K | 0.00% | −1,500−8.8% | Reduced |
| Harvest Investment Services, LLC | 15,466 | $977.3K | 0.22% | +15,466 | New |
| Atom Investors LP | 14,866 | $939.4K | 0.08% | −96−0.6% | Reduced |
| State Board of Administration of Florida Retirement System | 14,670 | $927.0K | 0.00% | 00.0% | Unchanged |
| Arizona State Retirement System | 13,834 | $874.2K | 0.01% | +653+5.0% | Added |
| Advisors Asset Management, Inc. | 13,596 | $859.1K | 0.02% | +3,346+32.6% | Added |
| ProShare Advisors LLC | 13,536 | $855.3K | 0.00% | −1,168−7.9% | Reduced |
| Leo Wealth, LLC | 13,445 | $849.6K | 0.07% | −2,555−16.0% | Reduced |
| Point72 (DIFC) Ltd | 13,149 | $830.9K | 0.07% | +6,496+97.6% | Added |
| Principal Financial Group Inc | 13,067 | $825.7K | 0.00% | −24,089−64.8% | Reduced |
| China Universal Asset Management Co., Ltd. | 12,778 | $807.4K | 0.08% | +96+0.8% | Added |
| Teacher Retirement System of Texas | 12,772 | $807.1K | 0.00% | +368+3.0% | Added |
| Police & Firemen's Retirement System of New Jersey | 12,359 | $781.0K | 0.01% | +704+6.0% | Added |
| Allianz Asset Management GmbH | 12,100 | $764.6K | 0.00% | +6,000+98.4% | Added |
| Great West Life Assurance Co | 11,578 | $733.0K | 0.00% | 00.0% | Unchanged |
| Profund Advisors LLC | 11,254 | $711.1K | 0.03% | −1,190−9.6% | Reduced |
| Raymond James Financial Inc | 10,546 | $666.4K | 0.00% | +10,546 | New |
| KLP Kapitalforvaltning AS | 10,200 | $644.5K | 0.00% | +900+9.7% | Added |
| Fiduciary Trust Co | 10,000 | $631.9K | 0.01% | −5,000−33.3% | Reduced |
| Cannon Financial Strategists, Inc. | 10,000 | $631.9K | 0.10% | 00.0% | Unchanged |
| Toth Financial Advisory Corp | 10,000 | $631.9K | 0.07% | +10,000 | New |
| Two Sigma Advisers, LP | 9,700 | $612.9K | 0.00% | −2,400−19.8% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 9,652 | $609.9K | 0.00% | +726+8.1% | Added |
| E. Ohman J:or Asset Management AB | 8,213 | $519.0K | 0.01% | +8,213 | New |
| Caption Management, LLC | 7,540 | $476.5K | 0.04% | +7,540 | New |
| Trexquant Investment LP | 7,083 | $447.6K | 0.01% | −31,641−81.7% | Reduced |
| Virtus Investment Advisers, Inc. | 7,052 | $445.6K | 0.15% | +606+9.4% | Added |
| CIBC World Markets Corp | 6,706 | $423.8K | 0.00% | −5,442−44.8% | Reduced |
| Prudential Financial Inc | 7,095 | $422.7K | 0.00% | +2,740+62.9% | Added |
| SG Americas Securities, LLC | 6,185 | $391.0K | 0.00% | −13,482−68.6% | Reduced |
| Tower Research Capital LLC (TRC) | 6,111 | $386.2K | 0.01% | +5,053+477.6% | Added |
| Gsa Capital Partners LLP | 6,097 | $385.0K | 0.03% | +1,028+20.3% | Added |
| E Fund Management Co., Ltd. | 5,761 | $364.0K | 0.02% | +365+6.8% | Added |
| Jasper Ridge Partners, L.P. | 5,639 | $356.3K | 0.01% | 00.0% | Unchanged |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 5,635 | $356.1K | 0.01% | +1,046+22.8% | Added |
| Ameritas Investment Partners, Inc. | 5,546 | $350.5K | 0.01% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 5,543 | $350.3K | 0.00% | +1,025+22.7% | Added |
| Public Employees Retirement Association of Colorado | 5,463 | $345.0K | 0.00% | 00.0% | Unchanged |
| Gotham Asset Management, LLC | 4,851 | $306.5K | 0.00% | +101+2.1% | Added |
| LPL Financial LLC | 4,805 | $303.6K | 0.00% | +591+14.0% | Added |
| Axq Capital, LP | 4,560 | $288.1K | 0.09% | +4,560 | New |
| Mackenzie Financial Corp | 4,411 | $278.7K | 0.00% | +68+1.6% | Added |
| Chicago Partners Investment Group LLC | 3,115 | $273.5K | 0.01% | −395−11.3% | Reduced |
| Mariner, LLC | 4,321 | $273.0K | 0.00% | −264−5.8% | Reduced |
| Tudor Investment Corp Et Al | 4,272 | $269.9K | 0.00% | −25,241−85.5% | Reduced |
| Xponance, Inc. | 4,272 | $269.9K | 0.00% | −93−2.1% | Reduced |
| Aigen Investment Management, LP | 4,214 | $266.3K | 0.04% | −3,487−45.3% | Reduced |
| Aquatic Capital Management LLC | 3,953 | $249.8K | 0.01% | −37,523−90.5% | Reduced |
| Jain Global LLC | 3,908 | $246.9K | 0.00% | +3,908 | New |
| Los Angeles Capital Management LLC | 3,872 | $244.7K | 0.00% | +3,872 | New |
| JGP Global Gestao de Recursos Ltda. | 3,824 | $241.6K | 0.12% | 00.0% | Unchanged |
| Freestone Capital Holdings, LLC | 3,700 | $233.8K | 0.01% | +3,700 | New |
| O'Shaughnessy Asset Management, LLC | 3,476 | $219.6K | 0.00% | +3,476 | New |
| CWM, LLC | 3,091 | $195.0K | 0.00% | +507+19.6% | Added |
| Mirae Asset Global Investments Co., Ltd. | 2,458 | $155.3K | 0.00% | +342+16.2% | Added |
| ZRC Wealth Management, LLC | 1,971 | $124.5K | 0.05% | 00.0% | Unchanged |
| Amalgamated Bank | 1,881 | $119.0K | 0.00% | 00.0% | Unchanged |
| Whittier Trust Co | 1,760 | $111.2K | 0.00% | 00.0% | Unchanged |
| KBC Group NV | 1,707 | $108.0K | 0.00% | −544−24.2% | Reduced |
| GF Fund Management Co. Ltd. | 1,573 | $99.4K | 0.00% | 00.0% | Unchanged |
| Quest Partners LLC | 1,470 | $92.9K | 0.01% | −5,137−77.8% | Reduced |
| Nisa Investment Advisors, LLC | 1,254 | $79.2K | 0.00% | +14+1.1% | Added |
| State of Wyoming | 1,065 | $67.3K | 0.01% | +1,065 | New |
| Advisor Group Holdings, Inc. | 979 | $61.9K | 0.00% | +389+65.9% | Added |
| Clearstead Advisors, LLC | 590 | $37.3K | 0.00% | +590 | New |
| SRS Capital Advisors, Inc. | 558 | $35.3K | 0.00% | +40+7.7% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 421 | $27.0K | 0.00% | +421 | New |
| Global Retirement Partners, LLC | 400 | $25.3K | 0.00% | +400 | New |
| Ameriflex Group, Inc. | 360 | $22.1K | 0.01% | 00.0% | Unchanged |
| Compagnie Lombard Odier SCmA | 250 | $15.8K | 0.00% | +250 | New |
| Jones Financial Companies LLLP | 231 | $14.5K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 224 | $14.2K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 229 | $14.0K | 0.00% | +26+12.8% | Added |
| Optiver Holding B.V. | 221 | $14.0K | 0.00% | +66+42.6% | Added |
| GAMMA Investing LLC | 211 | $13.3K | 0.00% | −70−24.9% | Reduced |
| First Horizon Advisors, Inc. | 200 | $12.6K | 0.00% | +200 | New |
| SBI Securities Co., Ltd. | 168 | $10.6K | 0.00% | −298−63.9% | Reduced |