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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2025

Institutional positions in Rhythm Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
227
0 vs. Q1 2025
Shares held
66.5M
+1.72M (+2.7%) vs. Q1 2025
Total value
$4.20B
+$767.9M (+22.3%) vs. Q1 2025
New holders
33
93 more added
Sold out
33
74 more reduced

1 institution that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 227 institutions
Q1 2021: 124 institutionsQ2 2021: 105 institutionsQ3 2021: 97 institutionsQ4 2021: 98 institutionsQ1 2022: 111 institutionsQ2 2022: 90 institutionsQ3 2022: 101 institutionsQ4 2022: 115 institutionsQ1 2023: 126 institutionsQ2 2023: 116 institutionsQ3 2023: 144 institutionsQ4 2023: 169 institutionsQ1 2024: 167 institutionsQ2 2024: 165 institutionsQ3 2024: 176 institutionsQ4 2024: 203 institutionsQ1 2025: 228 institutionsQ2 2025: 227 institutionsQ3 2025: 264 institutionsQ4 2025: 281 institutionsQ1 2026: 285 institutionsQ2 2026: 304 institutions
Value heldQ2 2025: $4.20B
Q1 2021: $1.01BQ2 2021: $905.6MQ3 2021: $626.3MQ4 2021: $483.6MQ1 2022: $562.7MQ2 2022: $190.8MQ3 2022: $1.45BQ4 2022: $1.81BQ1 2023: $1.08BQ2 2023: $1.09BQ3 2023: $1.56BQ4 2023: $3.07BQ1 2024: $2.95BQ2 2024: $2.85BQ3 2024: $3.55BQ4 2024: $3.63BQ1 2025: $3.44BQ2 2025: $4.20BQ3 2025: $7.20BQ4 2025: $7.80BQ1 2026: $6.42BQ2 2026: $8.55B
Institutions holding RYTM and their total value by quarter
QuarterHoldersValue
Q2 2026304$8.55B
Q1 2026285$6.42B
Q4 2025281$7.80B
Q3 2025264$7.20B
Q2 2025227$4.20B
Q1 2025228$3.44B
Q4 2024203$3.63B
Q3 2024176$3.55B
Q2 2024165$2.85B
Q1 2024167$2.95B
Q4 2023169$3.07B
Q3 2023144$1.56B
Q2 2023116$1.09B
Q1 2023126$1.08B
Q4 2022115$1.81B
Q3 2022101$1.45B
Q2 202290$190.8M
Q1 2022111$562.7M
Q4 202198$483.6M
Q3 202197$626.3M
Q2 2021105$905.6M
Q1 2021124$1.01B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q1 2025.

Institutions holding RYTM in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd5$00.00%−1−16.7%Reduced
Twin Peaks Wealth Advisors, LLC5$4820.00%+5New
Bare Financial Services, Inc10$6320.00%+10New
Whipplewood Advisors, LLC11$6950.00%−2−15.4%Reduced
CVA Family Office, LLC12$7580.00%00.0%Unchanged
UMA Financial Services, Inc.16$1.01K0.00%+16New
IFP Advisors, Inc15$1.20K0.00%+15New
Parallel Advisors, LLC19$1.20K0.00%00.0%Unchanged
Skopos Labs, Inc.21$1.33K0.00%+16+320.0%Added
ORG Partners LLC24$1.57K0.00%00.0%Unchanged
Farther Finance Advisors, LLC29$1.83K0.00%+15+107.1%Added
Parkside Financial Bank & Trust33$2.09K0.00%+13+65.0%Added
Versant Capital Management, Inc36$2.27K0.00%−19−34.5%Reduced
WPG Advisers, LLC57$3.60K0.00%+57New
Caitong International Asset Management Co., Ltd58$3.67K0.00%+58New
Bessemer Group Inc66$4.00K0.00%00.0%Unchanged
Allworth Financial LP64$4.04K0.00%+14+28.0%Added
EverSource Wealth Advisors, LLC65$4.11K0.00%+46+242.1%Added
South State Corp.71$4.49K0.00%00.0%Unchanged
Rothschild Investment LLC105$6.63K0.00%+15+16.7%Added
Bayforest Capital Ltd116$7.33K0.00%−3,018−96.3%Reduced
Essential Partners LLC120$7.58K0.00%+120New
Sterling Capital Management LLC132$8.34K0.00%+74+127.6%Added
Truvestments Capital LLC138$8.72K0.00%00.0%Unchanged
Smartleaf Asset Management LLC145$9.10K0.00%−110−43.1%Reduced
US Bancorp146$9.23K0.00%00.0%Unchanged
True Wealth Design, LLC147$9.29K0.00%+90+157.9%Added
SBI Securities Co., Ltd.168$10.6K0.00%−298−63.9%Reduced
First Horizon Advisors, Inc.200$12.6K0.00%+200New
GAMMA Investing LLC211$13.3K0.00%−70−24.9%Reduced
Optiver Holding B.V.221$14.0K0.00%+66+42.6%Added
Daiwa Securities Group Inc.229$14.0K0.00%+26+12.8%Added
Signaturefd, LLC224$14.2K0.00%00.0%Unchanged
Jones Financial Companies LLLP231$14.5K0.00%00.0%Unchanged
Compagnie Lombard Odier SCmA250$15.8K0.00%+250New
Ameriflex Group, Inc.360$22.1K0.01%00.0%Unchanged
Global Retirement Partners, LLC400$25.3K0.00%+400New
BNP PARIBAS ASSET MANAGEMENT Holding S.A.421$27.0K0.00%+421New
SRS Capital Advisors, Inc.558$35.3K0.00%+40+7.7%Added
Clearstead Advisors, LLC590$37.3K0.00%+590New
Advisor Group Holdings, Inc.979$61.9K0.00%+389+65.9%Added
State of Wyoming1,065$67.3K0.01%+1,065New
Nisa Investment Advisors, LLC1,254$79.2K0.00%+14+1.1%Added
Quest Partners LLC1,470$92.9K0.01%−5,137−77.8%Reduced
GF Fund Management Co. Ltd.1,573$99.4K0.00%00.0%Unchanged
KBC Group NV1,707$108.0K0.00%−544−24.2%Reduced
Whittier Trust Co1,760$111.2K0.00%00.0%Unchanged
Amalgamated Bank1,881$119.0K0.00%00.0%Unchanged
ZRC Wealth Management, LLC1,971$124.5K0.05%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.2,458$155.3K0.00%+342+16.2%Added
CWM, LLC3,091$195.0K0.00%+507+19.6%Added
O'Shaughnessy Asset Management, LLC3,476$219.6K0.00%+3,476New
Freestone Capital Holdings, LLC3,700$233.8K0.01%+3,700New
JGP Global Gestao de Recursos Ltda.3,824$241.6K0.12%00.0%Unchanged
Los Angeles Capital Management LLC3,872$244.7K0.00%+3,872New
Jain Global LLC3,908$246.9K0.00%+3,908New
Aquatic Capital Management LLC3,953$249.8K0.01%−37,523−90.5%Reduced
Aigen Investment Management, LP4,214$266.3K0.04%−3,487−45.3%Reduced
Tudor Investment Corp Et Al4,272$269.9K0.00%−25,241−85.5%Reduced
Xponance, Inc.4,272$269.9K0.00%−93−2.1%Reduced
Mariner, LLC4,321$273.0K0.00%−264−5.8%Reduced
Chicago Partners Investment Group LLC3,115$273.5K0.01%−395−11.3%Reduced
Mackenzie Financial Corp4,411$278.7K0.00%+68+1.6%Added
Axq Capital, LP4,560$288.1K0.09%+4,560New
LPL Financial LLC4,805$303.6K0.00%+591+14.0%Added
Gotham Asset Management, LLC4,851$306.5K0.00%+101+2.1%Added
Public Employees Retirement Association of Colorado5,463$345.0K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.5,543$350.3K0.00%+1,025+22.7%Added
Ameritas Investment Partners, Inc.5,546$350.5K0.01%00.0%Unchanged
Nelson, Van Denburg & Campbell Wealth Management Group, LLC5,635$356.1K0.01%+1,046+22.8%Added
Jasper Ridge Partners, L.P.5,639$356.3K0.01%00.0%Unchanged
E Fund Management Co., Ltd.5,761$364.0K0.02%+365+6.8%Added
Gsa Capital Partners LLP6,097$385.0K0.03%+1,028+20.3%Added
Tower Research Capital LLC (TRC)6,111$386.2K0.01%+5,053+477.6%Added
SG Americas Securities, LLC6,185$391.0K0.00%−13,482−68.6%Reduced
Prudential Financial Inc7,095$422.7K0.00%+2,740+62.9%Added
CIBC World Markets Corp6,706$423.8K0.00%−5,442−44.8%Reduced
Virtus Investment Advisers, Inc.7,052$445.6K0.15%+606+9.4%Added
Trexquant Investment LP7,083$447.6K0.01%−31,641−81.7%Reduced
Caption Management, LLC7,540$476.5K0.04%+7,540New
E. Ohman J:or Asset Management AB8,213$519.0K0.01%+8,213New
Zurcher Kantonalbank (Zurich Cantonalbank)9,652$609.9K0.00%+726+8.1%Added
Two Sigma Advisers, LP9,700$612.9K0.00%−2,400−19.8%Reduced
Fiduciary Trust Co10,000$631.9K0.01%−5,000−33.3%Reduced
Cannon Financial Strategists, Inc.10,000$631.9K0.10%00.0%Unchanged
Toth Financial Advisory Corp10,000$631.9K0.07%+10,000New
KLP Kapitalforvaltning AS10,200$644.5K0.00%+900+9.7%Added
Raymond James Financial Inc10,546$666.4K0.00%+10,546New
Profund Advisors LLC11,254$711.1K0.03%−1,190−9.6%Reduced
Great West Life Assurance Co11,578$733.0K0.00%00.0%Unchanged
Allianz Asset Management GmbH12,100$764.6K0.00%+6,000+98.4%Added
Police & Firemen's Retirement System of New Jersey12,359$781.0K0.01%+704+6.0%Added
Teacher Retirement System of Texas12,772$807.1K0.00%+368+3.0%Added
China Universal Asset Management Co., Ltd.12,778$807.4K0.08%+96+0.8%Added
Principal Financial Group Inc13,067$825.7K0.00%−24,089−64.8%Reduced
Point72 (DIFC) Ltd13,149$830.9K0.07%+6,496+97.6%Added
Leo Wealth, LLC13,445$849.6K0.07%−2,555−16.0%Reduced
ProShare Advisors LLC13,536$855.3K0.00%−1,168−7.9%Reduced
Advisors Asset Management, Inc.13,596$859.1K0.02%+3,346+32.6%Added
Arizona State Retirement System13,834$874.2K0.01%+653+5.0%Added