Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 305 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2025
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 228
- +26 vs. Q4 2024
- Shares held
- 64.8M
- +48.3K (+0.1%) vs. Q4 2024
- Total value
- $3.44B
- −$189.2M (−5.2%) vs. Q4 2024
- New holders
- 45
- 86 more added
- Sold out
- 19
- 69 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 305 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Mirae Asset Global ETFs Holdings Ltd. | 35,282 | $1.87M | 0.00% | +2,126+6.4% | Added |
| HighVista Strategies LLC | 35,039 | $1.86M | 0.72% | −2,387−6.4% | Reduced |
| Intech Investment Management LLC | 33,893 | $1.80M | 0.02% | +5,801+20.7% | Added |
| StemPoint Capital LP | 33,816 | $1.79M | 0.57% | −174,200−83.7% | Reduced |
| State of Wisconsin Investment Board | 33,025 | $1.75M | 0.00% | +763+2.4% | Added |
| MetLife Investment Management | 32,414 | $1.72M | 0.01% | −1,084−3.2% | Reduced |
| SEI Investments Co | 32,381 | $1.72M | 0.00% | −1,141−3.4% | Reduced |
| XTX Topco Ltd | 29,949 | $1.59M | 0.08% | +22,344+293.8% | Added |
| Tudor Investment Corp Et Al | 29,513 | $1.56M | 0.01% | +14,268+93.6% | Added |
| Corebridge Financial, Inc. | 26,821 | $1.42M | 0.01% | −399−1.5% | Reduced |
| Dark Forest Capital Management LP | 25,409 | $1.35M | 0.06% | +20,198+387.6% | Added |
| Squarepoint Ops LLC | 24,413 | $1.29M | 0.00% | +24,413 | New |
| Wellington Management Group LLP | 23,558 | $1.25M | 0.00% | −1,997−7.8% | Reduced |
| Assenagon Asset Management S.A. | 22,192 | $1.18M | 0.00% | +22,192 | New |
| Engineers Gate Manager LP | 21,883 | $1.16M | 0.02% | +2,700+14.1% | Added |
| SG Americas Securities, LLC | 19,667 | $1.04M | 0.00% | +19,667 | New |
| Fox Run Management, L.L.C. | 19,172 | $1.02M | 0.16% | +19,172 | New |
| STRS Ohio | 18,500 | $979.9K | 0.00% | +2,100+12.8% | Added |
| Stifel Financial Corp | 18,487 | $979.3K | 0.00% | −1,029−5.3% | Reduced |
| Schroder Investment Management Group | 17,618 | $965.5K | 0.00% | +17,618 | New |
| Ensign Peak Advisors, Inc | 17,659 | $935.4K | 0.00% | 00.0% | Unchanged |
| Captrust Financial Advisors | 17,357 | $919.4K | 0.00% | +17,357 | New |
| SummitTX Capital, L.P. | 17,343 | $918.7K | 0.04% | +17,343 | New |
| Victory Capital Management Inc | 17,326 | $917.8K | 0.00% | +174+1.0% | Added |
| Jefferies Financial Group Inc. | 17,100 | $905.8K | 0.02% | +17,100 | New |
| Quantinno Capital Management LP | 17,086 | $905.0K | 0.01% | +966+6.0% | Added |
| Handelsbanken Fonder AB | 17,021 | $902.0K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 16,850 | $892.5K | 0.00% | 00.0% | Unchanged |
| Leo Wealth, LLC | 16,000 | $847.5K | 0.12% | +16,000 | New |
| Bellevue Group AG | 15,550 | $823.7K | 0.02% | −8,046−34.1% | Reduced |
| HSBC Holdings PLC | 15,570 | $823.3K | 0.00% | −717−4.4% | Reduced |
| Fiduciary Trust Co | 15,000 | $794.5K | 0.01% | −5,000−25.0% | Reduced |
| Atom Investors LP | 14,962 | $792.5K | 0.10% | +3,357+28.9% | Added |
| ProShare Advisors LLC | 14,704 | $778.9K | 0.00% | −3,624−19.8% | Reduced |
| State Board of Administration of Florida Retirement System | 14,670 | $777.1K | 0.00% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 14,112 | $747.5K | 0.00% | +14,112 | New |
| Voleon Capital Management LP | 13,819 | $732.0K | 0.06% | +13,819 | New |
| American Century Companies Inc | 13,282 | $703.5K | 0.00% | −20,484−60.7% | Reduced |
| Arizona State Retirement System | 13,181 | $698.2K | 0.00% | −106−0.8% | Reduced |
| China Universal Asset Management Co., Ltd. | 12,682 | $671.8K | 0.06% | −349−2.7% | Reduced |
| Profund Advisors LLC | 12,444 | $659.2K | 0.03% | +1,963+18.7% | Added |
| Teacher Retirement System of Texas | 12,404 | $657.0K | 0.00% | −1,182−8.7% | Reduced |
| Creative Planning | 12,333 | $653.3K | 0.00% | +2,109+20.6% | Added |
| CIBC World Markets Corp | 12,148 | $643.5K | 0.01% | +7,025+137.1% | Added |
| Two Sigma Advisers, LP | 12,100 | $640.9K | 0.00% | −1,000−7.6% | Reduced |
| Exchange Traded Concepts, LLC | 11,912 | $631.0K | 0.01% | −463−3.7% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 11,655 | $617.4K | 0.01% | 00.0% | Unchanged |
| Great West Life Assurance Co | 11,578 | $615.0K | 0.00% | 00.0% | Unchanged |
| Persistent Asset Partners Ltd | 11,501 | $609.2K | 0.54% | −6,811−37.2% | Reduced |
| Advisors Asset Management, Inc. | 10,250 | $542.9K | 0.01% | +3,176+44.9% | Added |
| Cannon Financial Strategists, Inc. | 10,000 | $529.7K | 0.09% | 00.0% | Unchanged |
| KLP Kapitalforvaltning AS | 9,300 | $492.6K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 8,926 | $472.8K | 0.00% | −108−1.2% | Reduced |
| Aigen Investment Management, LP | 7,701 | $407.9K | 0.07% | +7,701 | New |
| Point72 (DIFC) Ltd | 6,653 | $352.4K | 0.03% | +6,653 | New |
| Quest Partners LLC | 6,607 | $350.0K | 0.04% | +6,606+660,600.0% | Added |
| Virtus Investment Advisers, Inc. | 6,446 | $341.4K | 0.09% | +6,446 | New |
| Bridgefront Capital, LLC | 6,414 | $339.8K | 0.10% | +1,810+39.3% | Added |
| Springhill Fund Asset Management (HK) Co Ltd | 6,277 | $332.5K | 1.59% | +6,277 | New |
| Allianz Asset Management GmbH | 6,100 | $323.1K | 0.00% | 00.0% | Unchanged |
| Fieldview Capital Management, LLC | 6,037 | $319.8K | 0.05% | +6,037 | New |
| BIT Capital GmbH | 6,013 | $318.5K | 0.04% | +6,013 | New |
| Y-Intercept (Hong Kong) Ltd | 5,966 | $316.0K | 0.02% | +100+1.7% | Added |
| Jasper Ridge Partners, L.P. | 5,639 | $298.7K | 0.01% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 5,546 | $293.8K | 0.01% | 00.0% | Unchanged |
| Entropy Technologies, LP | 5,502 | $291.4K | 0.03% | +5,502 | New |
| Public Employees Retirement Association of Colorado | 5,463 | $289.0K | 0.00% | 00.0% | Unchanged |
| E Fund Management Co., Ltd. | 5,396 | $285.8K | 0.01% | +5,396 | New |
| Quadrature Capital Ltd | 5,278 | $279.6K | 0.01% | +5,278 | New |
| Gsa Capital Partners LLP | 5,069 | $269.0K | 0.02% | +5,069 | New |
| Gotham Asset Management, LLC | 4,750 | $251.6K | 0.00% | −2,036−30.0% | Reduced |
| Prudential Financial Inc | 4,355 | $243.4K | 0.00% | +200+4.8% | Added |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 4,589 | $243.1K | 0.01% | +4,589 | New |
| Mariner, LLC | 4,585 | $242.9K | 0.00% | +60+1.3% | Added |
| The PNC Financial Services Group, Inc. | 4,518 | $239.3K | 0.00% | +4,214+1,386.2% | Added |
| Verition Fund Management LLC | 4,424 | $234.3K | 0.00% | −3,613−45.0% | Reduced |
| Xponance, Inc. | 4,365 | $231.2K | 0.00% | +197+4.7% | Added |
| Cinctive Capital Management LP | 4,356 | $230.7K | 0.02% | −78,399−94.7% | Reduced |
| Mackenzie Financial Corp | 4,343 | $230.0K | 0.00% | 00.0% | Unchanged |
| Chicago Partners Investment Group LLC | 3,510 | $226.9K | 0.01% | −186−5.0% | Reduced |
| LPL Financial LLC | 4,214 | $223.2K | 0.00% | +39+0.9% | Added |
| SIH Partners, LLLP | 3,980 | $210.8K | 0.02% | +3,980 | New |
| JGP Global Gestao de Recursos Ltda. | 3,824 | $202.6K | 0.15% | −1,554−28.9% | Reduced |
| Bayforest Capital Ltd | 3,134 | $166.0K | 0.07% | +3,134 | New |
| CWM, LLC | 2,584 | $137.0K | 0.00% | +1,240+92.3% | Added |
| KBC Group NV | 2,251 | $119.0K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 2,116 | $116.0K | 0.00% | +68+3.3% | Added |
| ZRC Wealth Management, LLC | 1,971 | $104.4K | 0.05% | 00.0% | Unchanged |
| Amalgamated Bank | 1,881 | $100.0K | 0.00% | +6+0.3% | Added |
| Whittier Trust Co | 1,760 | $93.2K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,573 | $83.3K | 0.00% | +283+21.9% | Added |
| Nisa Investment Advisors, LLC | 1,240 | $65.7K | 0.00% | −45−3.5% | Reduced |
| Tower Research Capital LLC (TRC) | 1,058 | $56.0K | 0.00% | −3,481−76.7% | Reduced |
| BI Asset Management Fondsmaeglerselskab A/S | 648 | $34.0K | 0.00% | +648 | New |
| Advisor Group Holdings, Inc. | 590 | $31.3K | 0.00% | −83−12.3% | Reduced |
| SRS Capital Advisors, Inc. | 518 | $27.4K | 0.00% | +64+14.1% | Added |
| SBI Securities Co., Ltd. | 466 | $24.7K | 0.00% | −200−30.0% | Reduced |
| Ameriflex Group, Inc. | 360 | $19.1K | 0.01% | 00.0% | Unchanged |
| GAMMA Investing LLC | 281 | $14.9K | 0.00% | +80+39.8% | Added |
| Smartleaf Asset Management LLC | 255 | $14.0K | 0.00% | +62+32.1% | Added |