Rhythm Pharmaceuticals, Inc.

RYTM

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0001649904

SEC filings (opens in a new tab)

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 305 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.

Q1 2025 vs. Q4 2024

How the institutions holding Rhythm Pharmaceuticals, Inc. changed between Q4 2024 and Q1 2025.

All holders in Q1 2025 All holders in Q4 2024

13F holders of RYTM: Q4 2024 compared with Q1 2025
Measure	Q4 2024	Of which not filed for Q1 2025	Q1 2025	Change
Holders	203	1	228	+26
Shares	64.9M	146.9K	64.8M	+48.3K (+0.1%)
Value	$3.63B	$8.22M	$3.44B	−$189.2M (−5.2%)

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (45)

Institutions that held Rhythm Pharmaceuticals, Inc. at the end of Q1 2025 but not at the end of Q4 2024.

Institutions new to RYTM in Q1 2025
Institution	Shares	Value	% of portfolio
Westfield Capital Management Co LP	1,341,092	$71.0M	0.35%
Siren, L.L.C.	277,533	$14.7M	0.83%
Cubist Systematic Strategies, LLC	173,822	$9.21M	0.12%
Nuveen, LLC	147,301	$7.80M	0.00%
Panagora Asset Management Inc	141,162	$7.48M	0.04%
Neuberger Berman Group LLC	67,939	$3.60M	0.00%
Point72 Asset Management, L.P.	63,842	$3.38M	0.01%
Kennedy Capital Management, Inc.	54,930	$2.91M	0.07%
Jump Financial, LLC	41,760	$2.21M	0.03%
Squarepoint Ops LLC	24,413	$1.29M	0.00%
Assenagon Asset Management S.A.	22,192	$1.18M	0.00%
SG Americas Securities, LLC	19,667	$1.04M	0.00%
Fox Run Management, L.L.C.	19,172	$1.02M	0.16%
Schroder Investment Management Group	17,618	$965.5K	0.00%
Captrust Financial Advisors	17,357	$919.4K	0.00%
SummitTX Capital, L.P.	17,343	$918.7K	0.04%
Jefferies Financial Group Inc.	17,100	$905.8K	0.02%
Leo Wealth, LLC	16,000	$847.5K	0.12%
Renaissance Technologies LLC	14,112	$747.5K	0.00%
Voleon Capital Management LP	13,819	$732.0K	0.06%
Aigen Investment Management, LP	7,701	$407.9K	0.07%
Point72 (DIFC) Ltd	6,653	$352.4K	0.03%
Virtus Investment Advisers, Inc.	6,446	$341.4K	0.09%
Springhill Fund Asset Management (HK) Co Ltd	6,277	$332.5K	1.59%
Fieldview Capital Management, LLC	6,037	$319.8K	0.05%
BIT Capital GmbH	6,013	$318.5K	0.04%
Entropy Technologies, LP	5,502	$291.4K	0.03%
E Fund Management Co., Ltd.	5,396	$285.8K	0.01%
Quadrature Capital Ltd	5,278	$279.6K	0.01%
Gsa Capital Partners LLP	5,069	$269.0K	0.02%
Nelson, Van Denburg & Campbell Wealth Management Group, LLC	4,589	$243.1K	0.01%
SIH Partners, LLLP	3,980	$210.8K	0.02%
Bayforest Capital Ltd	3,134	$166.0K	0.07%
BI Asset Management Fondsmaeglerselskab A/S	648	$34.0K	0.00%
Optiver Holding B.V.	155	$8.21K	0.00%
South State Corp.	71	$3.76K	0.00%
Allworth Financial LP	50	$3.15K	0.00%
True Wealth Design, LLC	57	$3.02K	0.00%
Versant Capital Management, Inc	55	$2.91K	0.00%
Northwestern Mutual Wealth Management Co	48	$2.54K	0.00%
Coldstream Capital Management Inc	30	$1.59K	0.00%
ORG Partners LLC	24	$1.20K	0.00%
Parkside Financial Bank & Trust	20	$1.06K	0.00%
Stephens Consulting, LLC	20	$1.06K	0.00%
Skopos Labs, Inc.	5	$265	0.00%

Sold out (19)

Institutions that held Rhythm Pharmaceuticals, Inc. at the end of Q4 2024 and filed for Q1 2025 without it.

Institutions that sold out of RYTM in Q1 2025
Institution	Shares, Q4 2024	Value, Q4 2024
Integral Health Asset Management, LLC	150,000	$8.40M
EAM Global Investors LLC	56,936	$3.19M
Crestline Management, LP	25,062	$1.40M
Bryce Point Capital, LLC	19,607	$1.10M
Castleark Management LLC	18,390	$1.03M
Omers Administration Corp	7,600	$425.4K
Farringdon Capital, Ltd.	6,854	$383.7K
Jain Global LLC	6,700	$375.1K
Virtus ETF Advisers LLC	6,280	$351.6K
Texas Treasury Safekeeping Trust Co	4,230	$237.0K
Raymond James Financial Inc	3,892	$217.9K
Freestone Capital Holdings, LLC	3,700	$207.1K
Simplex Trading, LLC	2,475	$138.0K
ORG Wealth Partners, LLC	1,206	$67.5K
State of Wyoming	1,084	$60.7K
Natixis	997	$55.8K
R Squared Ltd	780	$43.7K
Raleigh Capital Management Inc.	500	$28.0K
IFP Advisors, Inc	1	$56

Not filed for Q1 2025 yet (1)

Institutions that held Rhythm Pharmaceuticals, Inc. at the end of Q4 2024 and haven't filed a 13F for Q1 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding RYTM in Q4 2024 that haven't filed for Q1 2025
Institution	Shares, Q4 2024	Value, Q4 2024
Nuveen Asset Management, LLC	146,903	$8.22M