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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2025

Institutional positions in Rhythm Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
228
+26 vs. Q4 2024
Shares held
64.8M
+48.3K (+0.1%) vs. Q4 2024
Total value
$3.44B
−$189.2M (−5.2%) vs. Q4 2024
New holders
45
86 more added
Sold out
19
69 more reduced

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 228 institutions
Q1 2021: 124 institutionsQ2 2021: 105 institutionsQ3 2021: 97 institutionsQ4 2021: 98 institutionsQ1 2022: 111 institutionsQ2 2022: 90 institutionsQ3 2022: 101 institutionsQ4 2022: 115 institutionsQ1 2023: 126 institutionsQ2 2023: 116 institutionsQ3 2023: 144 institutionsQ4 2023: 169 institutionsQ1 2024: 167 institutionsQ2 2024: 165 institutionsQ3 2024: 176 institutionsQ4 2024: 203 institutionsQ1 2025: 228 institutionsQ2 2025: 227 institutionsQ3 2025: 264 institutionsQ4 2025: 281 institutionsQ1 2026: 285 institutionsQ2 2026: 304 institutions
Value heldQ1 2025: $3.44B
Q1 2021: $1.01BQ2 2021: $905.6MQ3 2021: $626.3MQ4 2021: $483.6MQ1 2022: $562.7MQ2 2022: $190.8MQ3 2022: $1.45BQ4 2022: $1.81BQ1 2023: $1.08BQ2 2023: $1.09BQ3 2023: $1.56BQ4 2023: $3.07BQ1 2024: $2.95BQ2 2024: $2.85BQ3 2024: $3.55BQ4 2024: $3.63BQ1 2025: $3.44BQ2 2025: $4.20BQ3 2025: $7.20BQ4 2025: $7.80BQ1 2026: $6.42BQ2 2026: $8.55B
Institutions holding RYTM and their total value by quarter
QuarterHoldersValue
Q2 2026304$8.55B
Q1 2026285$6.42B
Q4 2025281$7.80B
Q3 2025264$7.20B
Q2 2025227$4.20B
Q1 2025228$3.44B
Q4 2024203$3.63B
Q3 2024176$3.55B
Q2 2024165$2.85B
Q1 2024167$2.95B
Q4 2023169$3.07B
Q3 2023144$1.56B
Q2 2023116$1.09B
Q1 2023126$1.08B
Q4 2022115$1.81B
Q3 2022101$1.45B
Q2 202290$190.8M
Q1 2022111$562.7M
Q4 202198$483.6M
Q3 202197$626.3M
Q2 2021105$905.6M
Q1 2021124$1.01B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q4 2024.

Institutions holding RYTM in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd6$00.00%−4−40.0%Reduced
Skopos Labs, Inc.5$2650.00%+5New
Whipplewood Advisors, LLC13$5830.00%+2+18.2%Added
Hexagon Capital Partners LLC11$5830.00%+4+57.1%Added
CVA Family Office, LLC12$6360.00%00.0%Unchanged
Farther Finance Advisors, LLC14$7000.00%00.0%Unchanged
Parallel Advisors, LLC19$1.01K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC19$1.01K0.00%+7+58.3%Added
Parkside Financial Bank & Trust20$1.06K0.00%+20New
Stephens Consulting, LLC20$1.06K0.00%+20New
ORG Partners LLC24$1.20K0.00%+24New
Coldstream Capital Management Inc30$1.59K0.00%+30New
Northwestern Mutual Wealth Management Co48$2.54K0.00%+48New
Versant Capital Management, Inc55$2.91K0.00%+55New
True Wealth Design, LLC57$3.02K0.00%+57New
Sterling Capital Management LLC58$3.07K0.00%+2+3.6%Added
Allworth Financial LP50$3.15K0.00%+50New
South State Corp.71$3.76K0.00%+71New
Bessemer Group Inc66$4.00K0.00%+36+120.0%Added
Rothschild Investment LLC90$4.77K0.00%+25+38.5%Added
Lindbrook Capital, LLC129$6.83K0.00%+3+2.4%Added
Royal Bank of Canada131$7.00K0.00%−1,083−89.2%Reduced
Truvestments Capital LLC138$7.31K0.00%00.0%Unchanged
US Bancorp146$7.73K0.00%+5+3.5%Added
Optiver Holding B.V.155$8.21K0.00%+155New
Daiwa Securities Group Inc.203$11.0K0.00%00.0%Unchanged
Signaturefd, LLC224$11.9K0.00%+2+0.9%Added
Jones Financial Companies LLLP231$12.7K0.00%00.0%Unchanged
Smartleaf Asset Management LLC255$14.0K0.00%+62+32.1%Added
GAMMA Investing LLC281$14.9K0.00%+80+39.8%Added
Ameriflex Group, Inc.360$19.1K0.01%00.0%Unchanged
SBI Securities Co., Ltd.466$24.7K0.00%−200−30.0%Reduced
SRS Capital Advisors, Inc.518$27.4K0.00%+64+14.1%Added
Advisor Group Holdings, Inc.590$31.3K0.00%−83−12.3%Reduced
BI Asset Management Fondsmaeglerselskab A/S648$34.0K0.00%+648New
Tower Research Capital LLC (TRC)1,058$56.0K0.00%−3,481−76.7%Reduced
Nisa Investment Advisors, LLC1,240$65.7K0.00%−45−3.5%Reduced
GF Fund Management Co. Ltd.1,573$83.3K0.00%+283+21.9%Added
Whittier Trust Co1,760$93.2K0.00%00.0%Unchanged
Amalgamated Bank1,881$100.0K0.00%+6+0.3%Added
ZRC Wealth Management, LLC1,971$104.4K0.05%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.2,116$116.0K0.00%+68+3.3%Added
KBC Group NV2,251$119.0K0.00%00.0%Unchanged
CWM, LLC2,584$137.0K0.00%+1,240+92.3%Added
Bayforest Capital Ltd3,134$166.0K0.07%+3,134New
JGP Global Gestao de Recursos Ltda.3,824$202.6K0.15%−1,554−28.9%Reduced
SIH Partners, LLLP3,980$210.8K0.02%+3,980New
LPL Financial LLC4,214$223.2K0.00%+39+0.9%Added
Chicago Partners Investment Group LLC3,510$226.9K0.01%−186−5.0%Reduced
Mackenzie Financial Corp4,343$230.0K0.00%00.0%Unchanged
Cinctive Capital Management LP4,356$230.7K0.02%−78,399−94.7%Reduced
Xponance, Inc.4,365$231.2K0.00%+197+4.7%Added
Verition Fund Management LLC4,424$234.3K0.00%−3,613−45.0%Reduced
The PNC Financial Services Group, Inc.4,518$239.3K0.00%+4,214+1,386.2%Added
Mariner, LLC4,585$242.9K0.00%+60+1.3%Added
Nelson, Van Denburg & Campbell Wealth Management Group, LLC4,589$243.1K0.01%+4,589New
Prudential Financial Inc4,355$243.4K0.00%+200+4.8%Added
Gotham Asset Management, LLC4,750$251.6K0.00%−2,036−30.0%Reduced
Gsa Capital Partners LLP5,069$269.0K0.02%+5,069New
Quadrature Capital Ltd5,278$279.6K0.01%+5,278New
E Fund Management Co., Ltd.5,396$285.8K0.01%+5,396New
Public Employees Retirement Association of Colorado5,463$289.0K0.00%00.0%Unchanged
Entropy Technologies, LP5,502$291.4K0.03%+5,502New
Ameritas Investment Partners, Inc.5,546$293.8K0.01%00.0%Unchanged
Jasper Ridge Partners, L.P.5,639$298.7K0.01%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd5,966$316.0K0.02%+100+1.7%Added
BIT Capital GmbH6,013$318.5K0.04%+6,013New
Fieldview Capital Management, LLC6,037$319.8K0.05%+6,037New
Allianz Asset Management GmbH6,100$323.1K0.00%00.0%Unchanged
Springhill Fund Asset Management (HK) Co Ltd6,277$332.5K1.59%+6,277New
Bridgefront Capital, LLC6,414$339.8K0.10%+1,810+39.3%Added
Virtus Investment Advisers, Inc.6,446$341.4K0.09%+6,446New
Quest Partners LLC6,607$350.0K0.04%+6,606+660,600.0%Added
Point72 (DIFC) Ltd6,653$352.4K0.03%+6,653New
Aigen Investment Management, LP7,701$407.9K0.07%+7,701New
Zurcher Kantonalbank (Zurich Cantonalbank)8,926$472.8K0.00%−108−1.2%Reduced
KLP Kapitalforvaltning AS9,300$492.6K0.00%00.0%Unchanged
Cannon Financial Strategists, Inc.10,000$529.7K0.09%00.0%Unchanged
Advisors Asset Management, Inc.10,250$542.9K0.01%+3,176+44.9%Added
Persistent Asset Partners Ltd11,501$609.2K0.54%−6,811−37.2%Reduced
Great West Life Assurance Co11,578$615.0K0.00%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey11,655$617.4K0.01%00.0%Unchanged
Exchange Traded Concepts, LLC11,912$631.0K0.01%−463−3.7%Reduced
Two Sigma Advisers, LP12,100$640.9K0.00%−1,000−7.6%Reduced
CIBC World Markets Corp12,148$643.5K0.01%+7,025+137.1%Added
Creative Planning12,333$653.3K0.00%+2,109+20.6%Added
Teacher Retirement System of Texas12,404$657.0K0.00%−1,182−8.7%Reduced
Profund Advisors LLC12,444$659.2K0.03%+1,963+18.7%Added
China Universal Asset Management Co., Ltd.12,682$671.8K0.06%−349−2.7%Reduced
Arizona State Retirement System13,181$698.2K0.00%−106−0.8%Reduced
American Century Companies Inc13,282$703.5K0.00%−20,484−60.7%Reduced
Voleon Capital Management LP13,819$732.0K0.06%+13,819New
Renaissance Technologies LLC14,112$747.5K0.00%+14,112New
State Board of Administration of Florida Retirement System14,670$777.1K0.00%00.0%Unchanged
ProShare Advisors LLC14,704$778.9K0.00%−3,624−19.8%Reduced
Atom Investors LP14,962$792.5K0.10%+3,357+28.9%Added
Fiduciary Trust Co15,000$794.5K0.01%−5,000−25.0%Reduced
HSBC Holdings PLC15,570$823.3K0.00%−717−4.4%Reduced
Bellevue Group AG15,550$823.7K0.02%−8,046−34.1%Reduced
Leo Wealth, LLC16,000$847.5K0.12%+16,000New