Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Praxis Precision Medicines, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 309
- +20 vs. Q1 2026
- Shares held
- 33.7M
- +5.40M (+19.0%) vs. Q1 2026
- Total value
- $11.3B
- +$2.17B (+23.8%) vs. Q1 2026
- New holders
- 59
- 123 more added
- Sold out
- 39
- 93 more reduced
2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| State Street Corp | 1,026,443 | $343.7M | 0.01% | +142,205+16.1% | Added |
| Vanguard Capital Management LLC | 1,235,299 | $413.6M | 0.01% | +13,355+1.1% | Added |
| Vanguard Portfolio Management LLC | 1,335,185 | $447.0M | 0.02% | +578,437+76.4% | Added |
| Orbis Allan Gray Ltd | 1,529,788 | $512.2M | 1.76% | −942,692−38.1% | Reduced |
| Baker Bros. Advisors LP | 1,753,198 | $587.0M | 2.94% | 00.0% | Unchanged |
| Perceptive Advisors LLC | 2,035,986 | $681.6M | 10.58% | 00.0% | Unchanged |
| BlackRock, Inc. | 2,292,585 | $767.5M | 0.01% | −32,344−1.4% | Reduced |
| FMR LLC | 2,316,907 | $775.7M | 0.03% | +155,964+7.2% | Added |
| Jupiter Topco LLC | 3,421,374 | $1.15B | 0.47% | +3,421,374 | New |
| Persistent Asset Partners Ltd | 0 | $0 | 0.00% | −1,131−100.0% | Sold out |
| Ra Capital Management, L.P. | 0 | $0 | 0.00% | −373,787−100.0% | Sold out |
| Canada Pension Plan Investment Board | 0 | $0 | 0.00% | −40,130−100.0% | Sold out |
| Ally Bridge Group (NY) LLC | 0 | $0 | 0.00% | −32,810−100.0% | Sold out |
| Congress Asset Management Co | 0 | $0 | 0.00% | −24,839−100.0% | Sold out |
| EAM Investors, LLC | 0 | $0 | 0.00% | −18,995−100.0% | Sold out |
| Polygon Management Ltd. | 0 | $0 | 0.00% | −15,952−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −14,742−100.0% | Sold out |
| Braidwell LP | 0 | $0 | 0.00% | −9,976−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −9,064−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −6,626−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −1,660−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −1,640−100.0% | Sold out |
| Martingale Asset Management L P | 0 | $0 | 0.00% | −1,615−100.0% | Sold out |
| Centiva Capital, LP | 0 | $0 | 0.00% | −1,501−100.0% | Sold out |
| PSP Research LLC | 0 | $0 | 0.00% | −1,500−100.0% | Sold out |
| Fieldview Capital Management, LLC | 0 | $0 | 0.00% | −1,223−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −1,393−100.0% | Sold out |
| AlphaGrep UK Ltd | 0 | $0 | 0.00% | −1,134−100.0% | Sold out |
| QP Wealth Management, LLC | 0 | $0 | 0.00% | −995−100.0% | Sold out |
| CTC Alternative Strategies, Ltd. | 0 | $0 | 0.00% | −925−100.0% | Sold out |
| GTS Securities LLC | 0 | $0 | 0.00% | −837−100.0% | Sold out |
| Perbak Capital Partners LLP | 0 | $0 | 0.00% | −799−100.0% | Sold out |
| Pinnacle Associates Ltd | 0 | $0 | 0.00% | −744−100.0% | Sold out |
| Pinnacle Wealth Management Advisory Group, LLC | 0 | $0 | 0.00% | −744−100.0% | Sold out |
| Commonwealth Equity Services, LLC | 0 | $0 | 0.00% | −660−100.0% | Sold out |
| MML Investors Services, LLC | 0 | $0 | 0.00% | −639−100.0% | Sold out |
| Caitong International Asset Management Co., Ltd | 0 | $0 | 0.00% | −472−100.0% | Sold out |
| ABS Direct Equity Fund LLC | 0 | $0 | 0.00% | −400−100.0% | Sold out |
| Parallel Advisors, LLC | 0 | $0 | 0.00% | −124−100.0% | Sold out |
| MAI Capital Management | 0 | $0 | 0.00% | −106−100.0% | Sold out |
| Aster Capital Management (DIFC) Ltd | 0 | $0 | 0.00% | −260−100.0% | Sold out |
| Golden State Equity Partners | 0 | $0 | 0.00% | −24−100.0% | Sold out |
| AdvisorNet Financial, Inc | 0 | $0 | 0.00% | −20−100.0% | Sold out |
| Root Financial Partners, LLC | 0 | $0 | 0.00% | −7−100.0% | Sold out |
| Wealth Preservation Advisors, LLC | 0 | $0 | 0.00% | −5−100.0% | Sold out |
| Twin Peaks Wealth Advisors, LLC | 0 | $0 | 0.00% | −5−100.0% | Sold out |
| National Bank of Canada | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| Quadrant Capital Group LLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Janus Henderson Group PLC | – | – | – | – | Not filed |
| CWM, LLC | – | – | – | – | Not filed |