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Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Praxis Precision Medicines, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
309
+20 vs. Q1 2026
Shares held
33.7M
+5.40M (+19.0%) vs. Q1 2026
Total value
$11.3B
+$2.17B (+23.8%) vs. Q1 2026
New holders
59
123 more added
Sold out
39
93 more reduced

2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 309 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ2 2026: $11.3B
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q1 2026.

Institutions holding PRAX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Legal & General Group Plc19,030$6.37M0.00%+548+3.0%Added
Moody Aldrich Partners LLC19,066$6.38M1.15%−2,622−12.1%Reduced
Prudential Financial Inc19,541$6.54M0.01%−10,969−36.0%Reduced
SummitTX Capital, L.P.19,779$6.62M0.17%−17,059−46.3%Reduced
Susquehanna Portfolio Strategies, LLC21,126$7.07M0.11%−2,125−9.1%Reduced
Man Group plc21,164$7.09M0.01%+17,991+567.0%Added
Ishara Investments LP22,550$7.55M5.65%00.0%Unchanged
Vanguard Asset Management, Ltd22,634$7.58M0.01%+634+2.9%Added
Citigroup Inc23,599$7.90M0.00%+17,953+318.0%Added
Castleark Management LLC24,390$8.17M0.22%+24,390New
Allianz Asset Management GmbH25,744$8.62M0.01%+11,714+83.5%Added
Peregrine Capital Management LLC25,790$8.63M0.28%+25,790New
WCM Investment Management, LLC24,739$8.67M0.02%+24,739New
Manufacturers Life Insurance Company, The26,147$8.75M0.01%−3,946−13.1%Reduced
California State Teachers Retirement System26,603$8.91M0.01%−874−3.2%Reduced
Capital Fund Management S.A.27,058$9.06M0.06%+27,058New
TD Asset Management Inc27,162$9.09M0.01%−7,984−22.7%Reduced
Exome Asset Management LLC27,205$9.11M5.62%−18,264−40.2%Reduced
Mirae Asset Global ETFs Holdings Ltd.27,185$9.12M0.01%−559−2.0%Reduced
Wells Fargo & Company27,889$9.34M0.00%+16,275+140.1%Added
Clearbridge Investments, LLC27,981$9.37M0.01%+27,981New
Lord, Abbett & Co. LLC29,662$9.93M0.03%+43+0.1%Added
HighVista Strategies LLC30,210$10.1M2.31%+3,887+14.8%Added
Dimensional Fund Advisors LP31,574$10.6M0.00%+413+1.3%Added
Rhumbline Advisers32,347$10.8M0.01%−532−1.6%Reduced
B Group, Inc.33,237$11.1M6.32%00.0%Unchanged
University of Wisconsin Foundation34,730$11.6M9.21%+9,515+37.7%Added
Burkehill Global Management, LP35,000$11.7M0.42%00.0%Unchanged
UBS Asset Management Americas Inc36,187$12.1M0.00%−1,958−5.1%Reduced
StemPoint Capital LP37,243$12.5M2.16%−19,024−33.8%Reduced
PFM Health Sciences, LP38,575$12.9M1.12%+3,137+8.9%Added
Eventide Asset Management, LLC38,684$13.0M0.17%+44+0.1%Added
Integral Health Asset Management, LLC40,000$13.4M0.55%00.0%Unchanged
SEI Investments Co40,117$13.4M0.01%+10,592+35.9%Added
Squarepoint Ops LLC42,501$14.2M0.03%+40,491+2,014.5%Added
SEB Asset Management AB42,705$14.3M0.05%+42,705New
KVP Capital Advisors, LP42,900$14.4M10.54%00.0%Unchanged
California Public Employees Retirement System45,370$15.2M0.01%+3,207+7.6%Added
ArrowMark Colorado Holdings LLC46,030$15.4M0.64%−71,821−60.9%Reduced
Swiss National Bank46,100$15.4M0.01%−600−1.3%Reduced
Boxer Capital Management, LLC46,457$15.6M1.17%00.0%Unchanged
JPMorgan Chase & Co44,085$15.8M0.00%−36,095−45.0%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH48,118$16.1M0.02%+686+1.4%Added
Russell Investments Group, Ltd.51,033$17.1M0.01%+27,921+120.8%Added
Healthcare of Ontario Pension Plan Trust Fund56,840$19.0M0.03%+56,840New
AQR Capital Management LLC58,446$19.6M0.01%−210−0.4%Reduced
Candriam Luxembourg S.C.A.60,856$20.4M0.09%−2,772−4.4%Reduced
Raymond James Financial Inc61,980$20.8M0.01%+56,660+1,065.0%Added
Deutsche Bank AG64,263$21.5M0.01%+6,484+11.2%Added
Ameriprise Financial Inc64,295$21.5M0.00%+33,075+105.9%Added
Silverarc Capital Management, LLC65,679$22.0M2.45%−5,873−8.2%Reduced
72 Investment Holdings, LLC65,933$22.1M44.18%00.0%Unchanged
Alliancebernstein L.P.71,518$23.0M0.01%+43,818+158.2%Added
Ikarian Capital, LLC72,842$24.4M3.99%+1,261+1.8%Added
Ensign Peak Advisors, Inc72,952$24.4M0.04%+4,569+6.7%Added
Frontier Capital Management Co LLC74,207$24.8M0.23%+20,842+39.1%Added
ADAR1 Capital Management, LLC74,253$24.9M1.17%+72,753+4,850.2%Added
Alyeska Investment Group, L.P.80,846$27.1M0.07%+8,668+12.0%Added
Acuta Capital Partners, LLC82,796$27.7M19.32%−2,105−2.5%Reduced
First Turn Management, LLC83,528$28.0M2.99%+41,087+96.8%Added
Bank of New York Mellon Corp85,376$28.6M0.00%−1,671−1.9%Reduced
Velan Capital Investment Management LP88,781$29.7M18.21%−12,000−11.9%Reduced
Neuberger Berman Group LLC89,468$30.0M0.02%+63,508+244.6%Added
MetLife Investment Management90,543$30.3M0.14%+9,613+11.9%Added
Massachusetts Financial Services Co107,409$36.0M0.01%+100,021+1,353.8%Added
Nuveen, LLC108,032$36.2M0.01%+35,989+50.0%Added
Voya Investment Management LLC122,227$40.9M0.04%+94,093+334.4%Added
Wellington Management Group LLP125,867$42.1M0.01%−48,483−27.8%Reduced
UBS Group AG131,046$43.9M0.01%+22,600+20.8%Added
Marshall Wace, LLP137,008$45.9M0.04%+91,859+203.5%Added
Qube Research & Technologies Ltd152,475$51.0M0.06%+24,247+18.9%Added
T. Rowe Price Investment Management, Inc.160,477$53.7M0.04%−14,760−8.4%Reduced
Standard Life Aberdeen plc166,399$55.7M0.08%−6,085−3.5%Reduced
Soleus Capital Management, L.P.177,517$59.4M2.05%−153,000−46.3%Reduced
Affinity Asset Advisors, LLC185,000$61.9M3.03%+15,000+8.8%Added
Vanguard Fiduciary Trust Co188,161$63.0M0.01%+18,259+10.7%Added
BNP Paribas Arbitrage, SA188,409$63.1M0.03%+45,327+31.7%Added
Woodline Partners LP200,013$67.0M0.21%00.0%Unchanged
Westfield Capital Management Co LP218,898$73.3M0.24%+218,236+32,966.2%Added
Charles Schwab Investment Management Inc220,008$73.7M0.01%+4,561+2.1%Added
OrbiMed Advisors LLC230,100$77.0M1.46%+57,600+33.4%Added
American Century Companies Inc237,315$79.5M0.04%+109,061+85.0%Added
Northern Trust Corp240,887$80.6M0.01%+12,953+5.7%Added
Logos Global Management LP260,000$87.0M3.75%−25,000−8.8%Reduced
Vivo Capital, LLC271,116$90.8M8.29%−67,779−20.0%Reduced
Polar Capital Holdings Plc279,131$93.5M0.26%+279,131New
Pictet Asset Management Holding SA291,689$98.0M0.09%+5,045+1.8%Added
Franklin Resources Inc327,124$109.5M0.02%+51,001+18.5%Added
Norges Bank346,969$116.2M0.01%+346,969New
Hood River Capital Management LLC425,167$142.3M1.03%+66,549+18.6%Added
Invesco Ltd.537,548$180.0M0.01%+476,151+775.5%Added
Bank of America Corp546,930$183.1M0.01%+12,326+2.3%Added
Goldman Sachs Group Inc548,830$183.7M0.02%−161,904−22.8%Reduced
Cormorant Asset Management, LP640,000$214.3M10.98%−245,500−27.7%Reduced
Geode Capital Management, LLC748,039$250.5M0.01%+97,135+14.9%Added
Morgan Stanley854,112$285.9M0.02%+20,621+2.5%Added
Price T Rowe Associates Inc942,999$315.7M0.03%+312,147+49.5%Added
Driehaus Capital Management LLC959,048$321.1M1.86%+9,823+1.0%Added
Deerfield Management Company, L.P. (Series C)963,351$322.5M3.36%00.0%Unchanged
Adage Capital Partners GP, L.L.C.1,015,480$340.0M0.48%+199,741+24.5%Added