Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Praxis Precision Medicines, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 291
- +48 vs. Q4 2025
- Shares held
- 31.8M
- +3.79M (+13.5%) vs. Q4 2025
- Total value
- $10.2B
- +$1.98B (+24.0%) vs. Q4 2025
- New holders
- 80
- 121 more added
- Sold out
- 32
- 68 more reduced
7 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Tower Research Capital LLC (TRC) | 1,333 | $429.5K | 0.01% | +722+118.2% | Added |
| JustInvest LLC | 1,344 | $433.0K | 0.00% | +1,344 | New |
| XTX Topco Ltd | 1,344 | $433.0K | 0.01% | +1,344 | New |
| Abel Hall, LLC | 1,392 | $448.5K | 0.10% | +360+34.9% | Added |
| Swiss Life Asset Management Ltd | 1,402 | $451.7K | 0.00% | +456+48.2% | Added |
| CWM, LLC | 1,432 | $461.4K | 0.00% | +558+63.8% | Added |
| Mirae Asset Global Investments Co., Ltd. | 1,453 | $468.1K | 0.00% | +238+19.6% | Added |
| StoneX Group Inc. | 1,469 | $473.3K | 0.03% | −297−16.8% | Reduced |
| PSP Research LLC | 1,500 | $483.3K | 0.34% | −482−24.3% | Reduced |
| ADAR1 Capital Management, LLC | 1,500 | $483.3K | 0.03% | 00.0% | Unchanged |
| Centiva Capital, LP | 1,501 | $483.6K | 0.02% | +1,501 | New |
| US Bancorp | 1,539 | $495.9K | 0.00% | −286−15.7% | Reduced |
| Cerity Partners LLC | 1,599 | $515.2K | 0.00% | −2,328−59.3% | Reduced |
| HSBC Holdings PLC | 1,634 | $518.3K | 0.00% | +809+98.1% | Added |
| Martingale Asset Management L P | 1,615 | $520.3K | 0.01% | +559+52.9% | Added |
| Hudson Bay Capital Management LP | 1,640 | $528.4K | 0.00% | +1,640 | New |
| Simplex Trading, LLC | 1,660 | $534.8K | 0.02% | +1,660 | New |
| Brinker Capital Investments, LLC | 1,734 | $558.7K | 0.00% | −251−12.6% | Reduced |
| Bellevue Group AG | 1,757 | $566.1K | 0.01% | +1,757 | New |
| Virginia Retirement Systems Et Al | 1,800 | $579.9K | 0.00% | −1,700−48.6% | Reduced |
| Amundi | 1,802 | $580.6K | 0.00% | +1,012+128.1% | Added |
| Mercer Global Advisors Inc | 1,850 | $596.1K | 0.00% | +638+52.6% | Added |
| E Fund Management Co., Ltd. | 1,956 | $630.2K | 0.02% | +1,956 | New |
| Ethic Inc. | 1,990 | $641.2K | 0.01% | −203−9.3% | Reduced |
| Squarepoint Ops LLC | 2,010 | $647.6K | 0.00% | +120+6.3% | Added |
| Ameritas Investment Partners, Inc. | 2,113 | $680.8K | 0.02% | +247+13.2% | Added |
| Public Employees Retirement Association of Colorado | 2,390 | $770.0K | 0.00% | 00.0% | Unchanged |
| Xponance, Inc. | 2,420 | $779.7K | 0.01% | +656+37.2% | Added |
| Artia Global Partners LP | 2,500 | $805.5K | 0.18% | 00.0% | Unchanged |
| Guggenheim Capital LLC | 2,670 | $860.2K | 0.01% | +2,670 | New |
| ACT Capital Management, LLC | 2,700 | $869.9K | 0.68% | +2,000+285.7% | Added |
| Quarry LP | 2,750 | $886.0K | 0.18% | −1,250−31.3% | Reduced |
| LPL Financial LLC | 2,923 | $941.8K | 0.00% | +2,923 | New |
| Teacher Retirement System of Texas | 3,062 | $986.5K | 0.00% | +9+0.3% | Added |
| Man Group plc | 3,173 | $1.02M | 0.00% | −17,997−85.0% | Reduced |
| RE Advisers Corp | 3,300 | $1.06M | 0.03% | +3,300 | New |
| Quantinno Capital Management LP | 3,320 | $1.07M | 0.00% | +597+21.9% | Added |
| FORA Capital, LLC | 3,412 | $1.10M | 0.08% | +3,412 | New |
| Glenmede Trust Co NA | 3,410 | $1.10M | 0.01% | −2,878−45.8% | Reduced |
| Allstate Corp | 3,512 | $1.13M | 0.01% | +3,512 | New |
| Fifth Third Bancorp | 3,589 | $1.16M | 0.00% | +3,589 | New |
| STRS Ohio | 3,600 | $1.16M | 0.00% | +400+12.5% | Added |
| Millennium Management LLC | 3,831 | $1.23M | 0.00% | +3,831 | New |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 3,855 | $1.24M | 1.81% | +1,773+85.2% | Added |
| Coastal Bridge Advisors, LLC | 3,906 | $1.26M | 0.09% | −248−6.0% | Reduced |
| Nicholas Investment Partners, LP | 3,948 | $1.27M | 0.09% | +3,948 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 4,049 | $1.30M | 0.00% | +3,951+4,031.6% | Added |
| Royal Bank of Canada | 4,133 | $1.33M | 0.00% | +755+22.4% | Added |
| Hussman Strategic Advisors, Inc. | 4,200 | $1.35M | 0.29% | −4,200−50.0% | Reduced |
| Lion Point Capital, LP | 4,450 | $1.43M | 8.57% | 00.0% | Unchanged |
| Envestnet Asset Management Inc | 4,862 | $1.57M | 0.00% | −688−12.4% | Reduced |
| China Universal Asset Management Co., Ltd. | 4,942 | $1.59M | 0.12% | +67+1.4% | Added |
| ProShare Advisors LLC | 4,988 | $1.61M | 0.00% | −226−4.3% | Reduced |
| Ghisallo Capital Management LLC | 5,000 | $1.61M | 0.04% | +5,000 | New |
| Los Angeles Capital Management LLC | 5,060 | $1.63M | 0.01% | +4,508+816.7% | Added |
| KLP Kapitalforvaltning AS | 5,200 | $1.68M | 0.01% | +800+18.2% | Added |
| Raymond James Financial Inc | 5,320 | $1.71M | 0.00% | +85+1.6% | Added |
| Citigroup Inc | 5,646 | $1.82M | 0.00% | +60+1.1% | Added |
| State Board of Administration of Florida Retirement System | 5,902 | $1.90M | 0.00% | +96+1.7% | Added |
| Vanguard Investments Australia, Ltd. | 5,936 | $1.91M | 0.01% | +5,936 | New |
| Nisa Investment Advisors, LLC | 6,280 | $2.02M | 0.01% | −1,490−19.2% | Reduced |
| Arizona State Retirement System | 6,476 | $2.09M | 0.01% | +753+13.2% | Added |
| Trexquant Investment LP | 6,626 | $2.13M | 0.02% | −1,705−20.5% | Reduced |
| Vestmark Advisory Solutions, Inc. | 6,681 | $2.15M | 0.02% | +2,176+48.3% | Added |
| Intech Investment Management LLC | 6,977 | $2.25M | 0.02% | −1,757−20.1% | Reduced |
| Barclays PLC | 6,979 | $2.25M | 0.00% | −523,772−98.7% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 6,989 | $2.25M | 0.02% | +932+15.4% | Added |
| Profund Advisors LLC | 7,081 | $2.28M | 0.08% | −1,374−16.3% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 7,194 | $2.32M | 0.01% | +324+4.7% | Added |
| Massachusetts Financial Services Co | 7,388 | $2.38M | 0.00% | +4,072+122.8% | Added |
| State of New Jersey Common Pension Fund D | 8,058 | $2.60M | 0.01% | +1,040+14.8% | Added |
| Allspring Global Investments Holdings, LLC | 8,536 | $2.73M | 0.00% | +6,804+392.8% | Added |
| Susquehanna International Group, LLP | 8,517 | $2.74M | 0.00% | +6,174+263.5% | Added |
| New York State Common Retirement Fund | 8,749 | $2.82M | 0.00% | +1,449+19.8% | Added |
| Erste Asset Management GmbH | 10,500 | $2.90M | 0.03% | 00.0% | Unchanged |
| Prelude Capital Management, LLC | 9,064 | $2.92M | 0.22% | −6,974−43.5% | Reduced |
| Braidwell LP | 9,976 | $3.21M | 0.11% | +9,976 | New |
| Polen Capital Management LLC | 10,043 | $3.24M | 0.02% | +10,043 | New |
| Vanguard Global Advisers, LLC | 11,335 | $3.65M | 0.00% | +11,335 | New |
| Wells Fargo & Company | 11,614 | $3.74M | 0.00% | −13,621−54.0% | Reduced |
| Mutual of America Capital Management LLC | 12,473 | $4.02M | 0.05% | +12,473 | New |
| Allianz Asset Management GmbH | 14,030 | $4.52M | 0.01% | +11,630+484.6% | Added |
| Victory Capital Management Inc | 14,132 | $4.55M | 0.00% | +834+6.3% | Added |
| State of Wisconsin Investment Board | 14,642 | $4.72M | 0.01% | −589−3.9% | Reduced |
| ExodusPoint Capital Management, LP | 14,742 | $4.75M | 0.05% | +14,742 | New |
| Rafferty Asset Management, LLC | 15,188 | $4.89M | 0.02% | −7,052−31.7% | Reduced |
| J. Goldman & Co LP | 15,664 | $5.05M | 0.23% | +10,114+182.2% | Added |
| Polygon Management Ltd. | 15,952 | $5.14M | 1.01% | −7,000−30.5% | Reduced |
| Algert Global LLC | 16,168 | $5.21M | 0.08% | −64,472−80.0% | Reduced |
| Creative Planning | 16,286 | $5.25M | 0.00% | +5,443+50.2% | Added |
| Boothbay Fund Management, LLC | 17,587 | $5.67M | 0.13% | −3,387−16.1% | Reduced |
| Two Sigma Investments, LP | 17,598 | $5.67M | 0.00% | −5,500−23.8% | Reduced |
| Legal & General Group Plc | 18,482 | $5.95M | 0.00% | +501+2.8% | Added |
| EAM Investors, LLC | 18,995 | $6.12M | 0.71% | −1,946−9.3% | Reduced |
| Atom Investors LP | 21,196 | $6.83M | 0.49% | +4,709+28.6% | Added |
| Moody Aldrich Partners LLC | 21,688 | $6.99M | 1.26% | −20,043−48.0% | Reduced |
| Vanguard Asset Management, Ltd | 22,000 | $7.09M | 0.01% | +22,000 | New |
| Ishara Investments LP | 22,550 | $7.27M | 7.34% | −17,450−43.6% | Reduced |
| Russell Investments Group, Ltd. | 23,112 | $7.45M | 0.01% | +2,500+12.1% | Added |
| Susquehanna Portfolio Strategies, LLC | 23,251 | $7.49M | 0.11% | 00.0% | Unchanged |