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Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q3 2021

Institutional positions in Praxis Precision Medicines, Inc. as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
93
+13 vs. Q2 2021
Shares held
42.8M
+1.64M (+4.0%) vs. Q2 2021
Total value
$791.5M
+$40.5M (+5.4%) vs. Q2 2021
New holders
22
38 more added
Sold out
9
17 more reduced

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 93 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ3 2021: $791.5M
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q2 2021.

Institutions holding PRAX in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Ellevest, Inc.4$00.00%+4New
Lindbrook Capital, LLC26$00.00%+26New
Bessemer Group Inc62$1.00K0.00%00.0%Unchanged
Newbridge Financial Services Group, Inc.23$1.00K0.00%00.0%Unchanged
Captrust Financial Advisors53$1.00K0.00%+53New
UBS Group AG55$1.00K0.00%+55New
Quadrant Capital Group LLC124$2.00K0.00%+124New
Parallel Advisors, LLC166$3.00K0.00%+119+253.2%Added
Signaturefd, LLC141$3.00K0.00%+141New
US Bancorp230$4.00K0.00%+50+27.8%Added
Evolution Wealth Advisors, LLC257$5.00K0.00%−385−60.0%Reduced
Rockefeller Capital Management L.P.400$7.00K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,141$21.0K0.00%−3,149−73.4%Reduced
Macquarie Group Ltd1,239$23.0K0.00%+1,239New
Wells Fargo & Company1,528$28.0K0.00%+1,343+725.9%Added
Ameritas Investment Partners, Inc.2,483$46.0K0.00%+571+29.9%Added
Royal Bank of Canada3,609$67.0K0.00%+1,936+115.7%Added
Cubist Systematic Strategies, LLC7,410$137.0K0.00%−40,387−84.5%Reduced
Legal & General Group Plc7,902$147.0K0.00%+4,950+167.7%Added
Metropolitan Life Insurance Co8,298$153.4K0.00%+8,298New
Virtus ETF Advisers LLC10,260$190.0K0.08%−541−5.0%Reduced
Zuckerman Investment Group, LLC10,479$194.0K0.03%+10,479New
MetLife Investment Management10,839$200.4K0.00%00.0%Unchanged
Invesco Ltd.10,909$201.0K0.00%+10,909New
Boothbay Fund Management, LLC10,860$201.0K0.01%+10,860New
Bradley Foster & Sargent Inc11,000$203.0K0.00%00.0%Unchanged
Voloridge Investment Management, LLC11,548$214.0K0.00%−31,756−73.3%Reduced
Veritable, L.P.11,908$220.0K0.00%+11,908New
Voya Investment Management LLC11,958$221.0K0.00%+11,958New
Credit Suisse AG13,183$243.0K0.00%+2,357+21.8%Added
Schonfeld Strategic Advisors LLC14,300$265.0K0.00%+14,300New
Morgan Stanley14,484$267.0K0.00%−85,533−85.5%Reduced
Parametric Portfolio Associates LLC15,804$292.0K0.00%+15,804New
New York State Common Retirement Fund16,250$300.0K0.00%−4,739−22.6%Reduced
Cna Financial Corp16,841$311.0K0.08%+2,010+13.6%Added
American International Group, Inc.17,731$328.0K0.00%+4,065+29.7%Added
Manufacturers Life Insurance Company, The17,775$329.0K0.00%+3,232+22.2%Added
SG Americas Securities, LLC19,483$360.0K0.00%+19,483New
Price T Rowe Associates Inc20,760$384.0K0.00%+20,760New
State Board of Administration of Florida Retirement System20,861$386.0K0.00%+20,861New
Deutsche Bank AG21,123$391.0K0.00%+4,159+24.5%Added
JPMorgan Chase & Co23,026$425.0K0.00%+6,626+40.4%Added
Mirabella Financial Services LLP23,572$436.0K0.06%+23,572New
Bank of America Corp25,021$462.0K0.00%+10,750+75.3%Added
Values First Advisors, Inc.26,477$490.0K0.32%+26,477New
Two Sigma Advisers, LP30,000$555.0K0.00%+5,900+24.5%Added
Alta Wealth Advisors LLC31,028$574.0K0.42%00.0%Unchanged
State of Wisconsin Investment Board31,500$582.0K0.00%00.0%Unchanged
California State Teachers Retirement System35,358$654.0K0.00%+1,726+5.1%Added
Rhumbline Advisers35,638$659.0K0.00%+6,568+22.6%Added
Citigroup Inc38,115$705.0K0.00%+1,222+3.3%Added
Swiss National Bank48,000$888.0K0.00%00.0%Unchanged
Alps Advisors Inc55,043$1.02M0.01%−2,412−4.2%Reduced
Tekla Capital Management LLC75,000$1.39M0.04%00.0%Unchanged
Healthcare of Ontario Pension Plan Trust Fund82,000$1.52M0.00%+82,000New
Bank of New York Mellon Corp103,588$1.92M0.00%+34,657+50.3%Added
Goldman Sachs Group Inc108,879$2.01M0.00%+22,493+26.0%Added
Millennium Management LLC111,981$2.07M0.00%+50,667+82.6%Added
Raymond James & Associates118,294$2.19M0.00%+1,971+1.7%Added
Nuveen Asset Management, LLC125,219$2.32M0.00%+5,215+4.3%Added
Two Sigma Investments, LP126,608$2.34M0.01%−57,684−31.3%Reduced
Endurant Capital Management LP153,599$2.84M0.86%−45,966−23.0%Reduced
Marshall Wace North America L.P.168,497$3.12M0.01%+28,600+20.4%Added
Jennison Associates LLC195,422$3.61M0.00%−2,088−1.1%Reduced
Marshall Wace, LLP201,311$3.72M0.02%+12,475+6.6%Added
Charles Schwab Investment Management Inc237,915$4.40M0.00%+118,196+98.7%Added
Novo Holdings A/S250,000$4.62M0.24%−660,450−72.5%Reduced
Ghost Tree Capital, LLC250,000$4.62M1.52%+250,000New
Franklin Resources Inc274,806$5.08M0.00%00.0%Unchanged
Northern Trust Corp298,224$5.51M0.00%+75,038+33.6%Added
Woodline Partners LP308,746$5.71M0.09%−47,694−13.4%Reduced
Verition Fund Management LLC412,292$7.62M0.12%−1560.0%Reduced
Kingdon Capital Management, L.L.C.414,489$7.66M1.34%+164,489+65.8%Added
PFM Health Sciences, LP455,374$8.42M0.27%00.0%Unchanged
Laurion Capital Management LP494,579$9.14M0.13%+921+0.2%Added
State Street Corp507,904$9.39M0.00%+156,591+44.6%Added
Geode Capital Management, LLC584,254$10.8M0.00%+240,237+69.8%Added
Adage Capital Partners GP, L.L.C.612,081$11.3M0.02%+25,000+4.3%Added
Harvard Management Co Inc778,517$14.4M0.84%00.0%Unchanged
72 Investment Holdings, LLC988,995$18.3M22.84%00.0%Unchanged
Cormorant Asset Management, LP1,024,161$18.9M0.77%+160.0%Added
Point72 Asset Management, L.P.1,136,995$21.0M0.10%+350,000+44.5%Added
Artal Group S.A.1,200,000$22.2M0.55%00.0%Unchanged
Avoro Capital Advisors LLC1,600,000$29.6M0.47%00.0%Unchanged
Citadel Advisors LLC1,638,730$30.3M0.03%−220,183−11.8%Reduced
Alliancebernstein L.P.1,645,008$30.4M0.01%+225,640+15.9%Added
BlackRock Inc.2,144,669$39.7M0.00%+630,696+41.7%Added
Vida Ventures Advisors, LLC2,939,329$54.3M15.57%00.0%Unchanged
Vanguard Group Inc3,207,925$59.3M0.00%+660,172+25.9%Added
Janus Henderson Group PLC3,279,165$60.6M0.03%+300,680+10.1%Added
Eventide Asset Management, LLC3,810,599$70.5M0.93%+23,546+0.6%Added
FMR LLC4,656,829$86.1M0.01%−46,100−1.0%Reduced
Blackstone Group Inc.5,340,655$98.7M0.22%−460,832−7.9%Reduced
Monashee Investment Management LLC0$00.00%−100,000−100.0%Sold out
Sphera Funds Management Ltd.0$00.00%−75,600−100.0%Sold out
Alyeska Investment Group, L.P.0$00.00%−75,000−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−45,264−100.0%Sold out
Renaissance Technologies LLC0$00.00%−37,400−100.0%Sold out
Los Angeles Capital Management LLC0$00.00%−17,600−100.0%Sold out
Squarepoint Ops LLC0$00.00%−17,427−100.0%Sold out