Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Opko Health, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 221
- −3 vs. Q3 2025
- Shares held
- 199.6M
- +3.58M (+1.8%) vs. Q3 2025
- Total value
- $251.1M
- −$52.0M (−17.2%) vs. Q3 2025
- New holders
- 30
- 43 more added
- Sold out
- 33
- 77 more reduced
9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| IFP Advisors, Inc | 432 | $544 | 0.00% | −179−29.3% | Reduced |
| Rockefeller Capital Management L.P. | 401 | $505 | 0.00% | −1,000−71.4% | Reduced |
| Pittenger & Anderson Inc | 250 | $315 | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 228 | $287 | 0.00% | +1+0.4% | Added |
| Medallion Wealth Advisors, LLC | 200 | $252 | 0.00% | 00.0% | Unchanged |
| Hilton Head Capital Partners, LLC | 200 | $252 | 0.00% | +200 | New |
| Harbor Investment Advisory, LLC | 180 | $227 | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 108 | $135 | 0.00% | +107+10,700.0% | Added |
| Root Financial Partners, LLC | 100 | $126 | 0.00% | 00.0% | Unchanged |
| Boreal Capital Management LLC | 69 | $87 | 0.00% | 00.0% | Unchanged |
| Transamerica Financial Advisors, Inc. | 56 | $71 | 0.00% | −131−70.1% | Reduced |
| Larson Financial Group LLC | 40 | $50 | 0.00% | 00.0% | Unchanged |
| Dunhill Financial, LLC | 9 | $11 | 0.00% | +9 | New |
| Darwin Advisors, LLC | 5 | $6 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 2 | $3 | 0.00% | −51−96.2% | Reduced |
| Crewe Advisors LLC | 1 | $2 | 0.00% | 00.0% | Unchanged |
| Atlantic Union Bankshares Corp | 1 | $2 | 0.00% | +1 | New |
| LRI Investments, LLC | 1 | $1 | 0.00% | 00.0% | Unchanged |
| Centerpoint Advisors, LLC | 100 | $0 | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 72 | $0 | 0.00% | −244−77.2% | Reduced |
| Motiv8 Investments LLC | 300 | $0 | 0.00% | +300 | New |
| Weiss Asset Management LP | 0 | $0 | 0.00% | −1,130,771−100.0% | Sold out |
| State of Wyoming | 0 | $0 | 0.00% | −135,954−100.0% | Sold out |
| Csenge Advisory Group | 0 | $0 | 0.00% | −117,001−100.0% | Sold out |
| Humankind Investments LLC | 0 | $0 | 0.00% | −114,644−100.0% | Sold out |
| Phoenix Holdings Ltd. | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| SRS Capital Advisors, Inc. | 0 | $0 | 0.00% | −63,780−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −59,700−100.0% | Sold out |
| Brighton Jones LLC | 0 | $0 | 0.00% | −59,426−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −42,519−100.0% | Sold out |
| Kestra Advisory Services, LLC | 0 | $0 | 0.00% | −38,807−100.0% | Sold out |
| Norris Perne & French LLP | 0 | $0 | 0.00% | −32,000−100.0% | Sold out |
| Moseley Investment Management Inc | 0 | $0 | 0.00% | −25,153−100.0% | Sold out |
| X-Square Capital, LLC | 0 | $0 | 0.00% | −20,933−100.0% | Sold out |
| Sovereign Financial Group, Inc. | 0 | $0 | 0.00% | −20,078−100.0% | Sold out |
| Integrated Wealth Concepts LLC | 0 | $0 | 0.00% | −17,698−100.0% | Sold out |
| Equitable Holdings, Inc. | 0 | $0 | 0.00% | −17,056−100.0% | Sold out |
| Colony Group, LLC | 0 | $0 | 0.00% | −15,675−100.0% | Sold out |
| Kovack Advisors, Inc. | 0 | $0 | 0.00% | −15,000−100.0% | Sold out |
| MML Investors Services, LLC | 0 | $0 | 0.00% | −14,026−100.0% | Sold out |
| Merit Financial Group, LLC | 0 | $0 | 0.00% | −13,585−100.0% | Sold out |
| NorthCrest Asset Manangement, LLC | 0 | $0 | 0.00% | −12,470−100.0% | Sold out |
| Pallas Capital Advisors LLC | 0 | $0 | 0.00% | −11,710−100.0% | Sold out |
| Stillwater Capital Advisors, LLC | 0 | $0 | 0.00% | −11,380−100.0% | Sold out |
| Capital Square, LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Simplicity Wealth,LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Krilogy Financial LLC | 0 | $0 | 0.00% | −10,910−100.0% | Sold out |
| Wealthspire Advisors, LLC | 0 | $0 | 0.00% | −3,700−100.0% | Sold out |
| MAI Capital Management | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| Parkside Financial Bank & Trust | 0 | $0 | 0.00% | −395−100.0% | Sold out |
| Global Retirement Partners, LLC | 0 | $0 | 0.00% | −200−100.0% | Sold out |
| Salem Investment Counselors Inc | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −23−100.0% | Sold out |
| GWM Advisors LLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Glenmede Investment Management, LP | – | – | – | – | Not filed |
| Cubist Systematic Strategies, LLC | – | – | – | – | Not filed |
| CIBC Bancorp USA Inc. | – | – | – | – | Not filed |
| PBMares Wealth Management LLC | – | – | – | – | Not filed |
| Shell Asset Management Co | – | – | – | – | Not filed |
| Point72 (DIFC) Ltd | – | – | – | – | Not filed |
| Point72 Asia (Singapore) Pte. Ltd. | – | – | – | – | Not filed |
| FSA Wealth Management LLC | – | – | – | – | Not filed |
| Guerra Advisors Inc | – | – | – | – | Not filed |