Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Opko Health, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 221
- −3 vs. Q3 2025
- Shares held
- 199.6M
- +3.58M (+1.8%) vs. Q3 2025
- Total value
- $251.1M
- −$52.0M (−17.2%) vs. Q3 2025
- New holders
- 30
- 43 more added
- Sold out
- 33
- 77 more reduced
9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Centerpoint Advisors, LLC | 100 | $0 | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 72 | $0 | 0.00% | −244−77.2% | Reduced |
| Motiv8 Investments LLC | 300 | $0 | 0.00% | +300 | New |
| LRI Investments, LLC | 1 | $1 | 0.00% | 00.0% | Unchanged |
| Crewe Advisors LLC | 1 | $2 | 0.00% | 00.0% | Unchanged |
| Atlantic Union Bankshares Corp | 1 | $2 | 0.00% | +1 | New |
| SBI Securities Co., Ltd. | 2 | $3 | 0.00% | −51−96.2% | Reduced |
| Darwin Advisors, LLC | 5 | $6 | 0.00% | 00.0% | Unchanged |
| Dunhill Financial, LLC | 9 | $11 | 0.00% | +9 | New |
| Larson Financial Group LLC | 40 | $50 | 0.00% | 00.0% | Unchanged |
| Transamerica Financial Advisors, Inc. | 56 | $71 | 0.00% | −131−70.1% | Reduced |
| Boreal Capital Management LLC | 69 | $87 | 0.00% | 00.0% | Unchanged |
| Root Financial Partners, LLC | 100 | $126 | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 108 | $135 | 0.00% | +107+10,700.0% | Added |
| Harbor Investment Advisory, LLC | 180 | $227 | 0.00% | 00.0% | Unchanged |
| Medallion Wealth Advisors, LLC | 200 | $252 | 0.00% | 00.0% | Unchanged |
| Hilton Head Capital Partners, LLC | 200 | $252 | 0.00% | +200 | New |
| Northwestern Mutual Wealth Management Co | 228 | $287 | 0.00% | +1+0.4% | Added |
| Pittenger & Anderson Inc | 250 | $315 | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 401 | $505 | 0.00% | −1,000−71.4% | Reduced |
| IFP Advisors, Inc | 432 | $544 | 0.00% | −179−29.3% | Reduced |
| Rothschild Investment LLC | 449 | $566 | 0.00% | −230−33.9% | Reduced |
| US Bancorp | 500 | $630 | 0.00% | −600−54.5% | Reduced |
| True Wealth Design, LLC | 872 | $1.10K | 0.00% | +6+0.7% | Added |
| Salomon & Ludwin, LLC | 921 | $1.18K | 0.00% | −30−3.2% | Reduced |
| PFS Partners, LLC | 1,100 | $1.39K | 0.00% | 00.0% | Unchanged |
| Godfrey Financial Associates, Inc. | 1,250 | $1.57K | 0.00% | +1,250 | New |
| Nisa Investment Advisors, LLC | 1,312 | $1.65K | 0.00% | −3,160−70.7% | Reduced |
| Optiver Holding B.V. | 1,393 | $1.75K | 0.00% | −1,363−49.5% | Reduced |
| Aster Capital Management (DIFC) Ltd | 1,408 | $1.77K | 0.00% | −3,272−69.9% | Reduced |
| CoreCap Advisors, LLC | 1,600 | $2.02K | 0.00% | 00.0% | Unchanged |
| Essential Partners LLC | 1,716 | $2.16K | 0.00% | −3,666−68.1% | Reduced |
| Smartleaf Asset Management LLC | 2,757 | $3.58K | 0.00% | 00.0% | Unchanged |
| Gables Capital Management Inc. | 3,000 | $3.78K | 0.00% | 00.0% | Unchanged |
| Altshuler Shaham Ltd | 3,292 | $4.21K | 0.00% | +2,160+190.8% | Added |
| CIBC Private Wealth Group, LLC | 5,000 | $6.30K | 0.00% | +5,000 | New |
| EverSource Wealth Advisors, LLC | 5,625 | $7.09K | 0.00% | −1,168−17.2% | Reduced |
| National Bank of Canada | 6,200 | $7.75K | 0.00% | 00.0% | Unchanged |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 6,045 | $8.00K | 0.00% | +2,268+60.0% | Added |
| Steward Partners Investment Advisory, LLC | 7,110 | $8.96K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 8,151 | $10.3K | 0.00% | +2,166+36.2% | Added |
| Aventura Private Wealth, LLC | 8,400 | $10.6K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 9,128 | $11.5K | 0.00% | −12,415−57.6% | Reduced |
| KLCM Advisors, Inc. | 10,000 | $12.6K | 0.00% | 00.0% | Unchanged |
| Greenbush Financial Group, LLC | 10,000 | $12.6K | 0.00% | 00.0% | Unchanged |
| MRP Capital Investments, LLC | 10,000 | $12.6K | 0.01% | 00.0% | Unchanged |
| SEI Investments Co | 10,163 | $12.8K | 0.00% | 00.0% | Unchanged |
| Diversified Trust Co | 10,374 | $13.1K | 0.00% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 10,637 | $13.4K | 0.00% | +10,637 | New |
| HBK Sorce Advisory LLC | 11,057 | $13.7K | 0.00% | −2,470−18.3% | Reduced |
| Atomi Financial Group, Inc. | 11,500 | $14.5K | 0.00% | +11,500 | New |
| Buckingham Strategic Partners | 11,664 | $14.7K | 0.00% | −6,367−35.3% | Reduced |
| Traphagen Investment Advisors LLC | 11,680 | $14.7K | 0.00% | 00.0% | Unchanged |
| Mill Creek Capital Advisors, LLC | 12,383 | $15.6K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 12,929 | $16.0K | 0.00% | +1,819+16.4% | Added |
| Formidable Asset Management, LLC | 11,296 | $17.5K | 0.00% | −3,000−21.0% | Reduced |
| FMR LLC | 14,087 | $17.8K | 0.00% | −2,477−15.0% | Reduced |
| Jones Financial Companies LLLP | 14,125 | $17.8K | 0.00% | 00.0% | Unchanged |
| Colony Family Offices, LLC | 14,729 | $18.6K | 0.00% | 00.0% | Unchanged |
| Sanctuary Advisors, LLC | 14,758 | $18.6K | 0.00% | −909−5.8% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 14,823 | $18.7K | 0.00% | 00.0% | Unchanged |
| Key Financial Inc | 15,250 | $19.2K | 0.00% | +4,250+38.6% | Added |
| Jump Financial, LLC | 15,277 | $19.2K | 0.00% | +15,277 | New |
| Stifel Financial Corp | 15,358 | $19.4K | 0.00% | −1,500−8.9% | Reduced |
| Sigma Planning Corp | 15,807 | $19.9K | 0.00% | 00.0% | Unchanged |
| Commons Capital, LLC | 16,300 | $20.5K | 0.01% | 00.0% | Unchanged |
| Citigroup Inc | 16,542 | $20.8K | 0.00% | −16,206−49.5% | Reduced |
| CAPROCK Group, Inc. | 16,770 | $21.1K | 0.00% | 00.0% | Unchanged |
| Shufro Rose & Co LLC | 17,000 | $21.4K | 0.00% | 00.0% | Unchanged |
| CIBC World Markets Inc. | 17,228 | $21.7K | 0.00% | −12,700−42.4% | Reduced |
| Cerity Partners LLC | 17,382 | $21.9K | 0.00% | −17,184−49.7% | Reduced |
| Quantinno Capital Management LP | 17,716 | $22.3K | 0.00% | +17,716 | New |
| Principal Financial Group Inc | 17,752 | $22.4K | 0.00% | −10,985−38.2% | Reduced |
| Westmount Partners, LLC | 18,550 | $23.4K | 0.01% | +2,000+12.1% | Added |
| Swiss Life Asset Management Ltd | 19,164 | $24.1K | 0.00% | 00.0% | Unchanged |
| Cumberland Advisors Inc | 19,500 | $24.6K | 0.01% | 00.0% | Unchanged |
| Capital Advisors Inc | 370,000 | $25.3K | 0.00% | 00.0% | Unchanged |
| Sax Wealth Advisors, LLC | 20,298 | $25.6K | 0.00% | −82−0.4% | Reduced |
| Zacks Investment Management | 21,322 | $26.9K | 0.00% | +21,322 | New |
| StoneX Group Inc. | 21,599 | $27.2K | 0.00% | +21,599 | New |
| CIBC Asset Management Inc | 21,918 | $27.6K | 0.00% | 00.0% | Unchanged |
| LPL Financial LLC | 22,458 | $28.3K | 0.00% | −8,477−27.4% | Reduced |
| Sterling Capital Management LLC | 23,720 | $29.9K | 0.00% | −4,676−16.5% | Reduced |
| Arrow Financial Corp | 25,000 | $31.5K | 0.00% | 00.0% | Unchanged |
| SlateStone Wealth, LLC | 25,770 | $32.0K | 0.00% | 00.0% | Unchanged |
| Cim Investment Mangement Inc | 25,804 | $32.5K | 0.01% | 00.0% | Unchanged |
| Prudential Financial Inc | 26,366 | $33.2K | 0.00% | −28,406−51.9% | Reduced |
| State of Wisconsin Investment Board | 26,437 | $33.3K | 0.00% | −12,660−32.4% | Reduced |
| Mackenzie Financial Corp | 25,843 | $33.5K | 0.00% | 00.0% | Unchanged |
| CIBC World Markets Corp | 27,225 | $34.3K | 0.00% | +27,225 | New |
| Atom Investors LP | 28,258 | $35.6K | 0.00% | −13,614−32.5% | Reduced |
| EP Wealth Advisors, LLC | 29,446 | $37.1K | 0.00% | +29,446 | New |
| Brinker Capital Investments, LLC | 30,000 | $37.8K | 0.00% | −96−0.3% | Reduced |
| Fisher Asset Management, LLC | 30,000 | $37.8K | 0.00% | 00.0% | Unchanged |
| IPG Investment Advisors LLC | 30,000 | $37.8K | 0.01% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 31,889 | $40.2K | 0.00% | 00.0% | Unchanged |
| STRS Ohio | 31,900 | $40.2K | 0.00% | 00.0% | Unchanged |
| Diversify Wealth Management, LLC | 30,000 | $40.2K | 0.00% | 00.0% | Unchanged |
| Operose Advisors LLC | 32,000 | $40.3K | 0.01% | 00.0% | Unchanged |
| Xponance, Inc. | 32,361 | $40.8K | 0.00% | +191+0.6% | Added |