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Opko Health, Inc.

OPK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000944809

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

Q4 2025 vs. Q3 2025

How the institutions holding Opko Health, Inc. changed between Q3 2025 and Q4 2025.

All holders in Q4 2025All holders in Q3 2025

13F holders of OPK: Q3 2025 compared with Q4 2025
MeasureQ3 2025Of which not filed for Q4 2025Q4 2025Change
Holders2339221−3
Shares196.3M298.1K199.6M+3.58M (+1.8%)
Value$303.6M$462.3K$251.1M−$52.0M (−17.2%)

9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (30)

Institutions that held Opko Health, Inc. at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to OPK in Q4 2025
InstitutionSharesValue% of portfolio
Clearstead Advisors, LLC882,367$1.11M0.01%
HRT Financial LP675,483$851.0K0.00%
Gsa Capital Partners LLP621,328$783.0K0.07%
XTX Topco Ltd342,757$431.9K0.01%
Millennium Management LLC265,268$334.2K0.00%
Balyasny Asset Management LLC198,821$250.5K0.00%
Mirabella Financial Services LLP193,722$244.1K0.02%
Quantbot Technologies LP122,747$154.7K0.01%
Virtu Financial LLC115,298$145.0K0.01%
Glenmede Trust Co NA113,483$143.0K0.00%
Y-Intercept (Hong Kong) Ltd112,930$142.3K0.00%
Qube Research & Technologies Ltd102,763$129.5K0.00%
Quadrature Capital Ltd91,702$115.5K0.00%
Brevan Howard Capital Management LP85,348$107.5K0.00%
Wellington Grp LLC60,000$75.6K0.03%
Warren Averett Asset Management, LLC34,727$43.8K0.00%
EP Wealth Advisors, LLC29,446$37.1K0.00%
CIBC World Markets Corp27,225$34.3K0.00%
StoneX Group Inc.21,599$27.2K0.00%
Zacks Investment Management21,322$26.9K0.00%
Quantinno Capital Management LP17,716$22.3K0.00%
Jump Financial, LLC15,277$19.2K0.00%
Atomi Financial Group, Inc.11,500$14.5K0.00%
ExodusPoint Capital Management, LP10,637$13.4K0.00%
CIBC Private Wealth Group, LLC5,000$6.30K0.00%
Godfrey Financial Associates, Inc.1,250$1.57K0.00%
Hilton Head Capital Partners, LLC200$2520.00%
Dunhill Financial, LLC9$110.00%
Atlantic Union Bankshares Corp1$20.00%
Motiv8 Investments LLC300$00.00%

Sold out (33)

Institutions that held Opko Health, Inc. at the end of Q3 2025 and filed for Q4 2025 without it.

Not filed for Q4 2025 yet (9)

Institutions that held Opko Health, Inc. at the end of Q3 2025 and haven't filed a 13F for Q4 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding OPK in Q3 2025 that haven't filed for Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Glenmede Investment Management, LP113,413$175.8K
Cubist Systematic Strategies, LLC72,127$111.8K
CIBC Bancorp USA Inc.43,868$68.0K
PBMares Wealth Management LLC27,021$41.9K
Shell Asset Management Co16,596$26.0K
Point72 (DIFC) Ltd11,450$17.7K
Point72 Asia (Singapore) Pte. Ltd.9,624$14.9K
FSA Wealth Management LLC3,950$6.12K
Guerra Advisors Inc1$2