Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 149
- +13 vs. Q1 2026
- Shares held
- 364.6M
- +41.2M (+12.8%) vs. Q1 2026
- Total value
- $875.1M
- +$370.5M (+73.4%) vs. Q1 2026
- New holders
- 43
- 37 more added
- Sold out
- 30
- 36 more reduced
1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| SBI Securities Co., Ltd. | 19,205 | $46.1K | 0.00% | +15,124+370.6% | Added |
| Principal Financial Group Inc | 19,034 | $45.7K | 0.00% | +19,034 | New |
| Credit Agricole S A | 18,975 | $45.5K | 0.00% | 00.0% | Unchanged |
| Captrust Financial Advisors | 15,321 | $36.8K | 0.00% | −129−0.8% | Reduced |
| Callan Family Office, LLC | 14,090 | $33.8K | 0.00% | 00.0% | Unchanged |
| Truist Financial Corp | 14,000 | $33.6K | 0.00% | 00.0% | Unchanged |
| CIBC Bancorp USA Inc. | 13,740 | $33.0K | 0.00% | −1,786,260−99.2% | Reduced |
| Gotham Asset Management, LLC | 13,627 | $32.7K | 0.00% | +13,627 | New |
| CIBC Asset Management Inc | 13,102 | $31.4K | 0.00% | −26,418−66.8% | Reduced |
| Royal Bank of Canada | 12,650 | $30.0K | 0.00% | +11,099+715.6% | Added |
| HBK Sorce Advisory LLC | 11,786 | $28.9K | 0.00% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 11,741 | $28.2K | 0.00% | +11,741 | New |
| Apollon Wealth Management, LLC | 11,378 | $27.3K | 0.00% | +11,378 | New |
| Mariner, LLC | 11,239 | $27.0K | 0.00% | +167+1.5% | Added |
| Wealth Enhancement Advisory Services, LLC | 12,139 | $26.9K | 0.00% | −249−2.0% | Reduced |
| Perennial Investment Advisors, LLC | 10,990 | $26.4K | 0.00% | 00.0% | Unchanged |
| Cetera Investment Advisers | 10,524 | $25.3K | 0.00% | −2,109−16.7% | Reduced |
| NBT Bank N A | 10,000 | $24.0K | 0.00% | 00.0% | Unchanged |
| Berger Financial Group, Inc | 10,000 | $24.0K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 8,540 | $20.5K | 0.00% | +8,540 | New |
| California State Teachers Retirement System | 3,427 | $8.22K | 0.00% | +3,427 | New |
| Nisa Investment Advisors, LLC | 2,592 | $6.22K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 1,461 | $3.51K | 0.00% | 00.0% | Unchanged |
| UMA Financial Services, Inc. | 1,412 | $3.39K | 0.00% | 00.0% | Unchanged |
| Rialto Wealth Management, LLC | 1,313 | $3.15K | 0.00% | 00.0% | Unchanged |
| Cassaday & Co Wealth Management LLC | 1,000 | $2.40K | 0.00% | 00.0% | Unchanged |
| Global Retirement Partners, LLC | 1,000 | $2.40K | 0.00% | +1,000 | New |
| Massmutual Trust Co FSB | 957 | $2.30K | 0.00% | +957 | New |
| Sterling Capital Management LLC | 874 | $2.10K | 0.00% | +874 | New |
| Avion Wealth | 1,115 | $2.00K | 0.00% | −218−16.4% | Reduced |
| Aster Capital Management (DIFC) Ltd | 743 | $1.78K | 0.00% | +743 | New |
| Fortitude Family Office, LLC | 706 | $1.69K | 0.00% | 00.0% | Unchanged |
| Basecamp Wealth Advisors LLC | 691 | $1.66K | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 500 | $1.20K | 0.00% | −3−0.6% | Reduced |
| Steward Partners Investment Advisory, LLC | 400 | $960 | 0.00% | −100−20.0% | Reduced |
| Jones Financial Companies LLLP | 356 | $908 | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 300 | $720 | 0.00% | −35−10.4% | Reduced |
| Allworth Financial LP | 263 | $632 | 0.00% | +263 | New |
| Parallel Advisors, LLC | 247 | $593 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 163 | $390 | 0.00% | −500−75.4% | Reduced |
| Caitong International Asset Management Co., Ltd | 157 | $377 | 0.00% | −196−55.5% | Reduced |
| Syntax Research, Inc. | 142 | $341 | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 100 | $240 | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 100 | $240 | 0.00% | +100 | New |
| SRS Capital Advisors, Inc. | 41 | $98 | 0.00% | 00.0% | Unchanged |
| HM Payson & Co | 37 | $89 | 0.00% | 00.0% | Unchanged |
| Blume Capital Management, Inc. | 5 | $12 | 0.00% | +5 | New |
| Farther Finance Advisors, LLC | 2 | $5 | 0.00% | −253−99.2% | Reduced |
| Covestor Ltd | 81 | $0 | 0.00% | 00.0% | Unchanged |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −2,665,938−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −2,376,304−100.0% | Sold out |
| Hennion & Walsh Asset Management, Inc. | 0 | $0 | 0.00% | −848,138−100.0% | Sold out |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −399,700−100.0% | Sold out |
| Catalyst Funds Management Pty Ltd | 0 | $0 | 0.00% | −207,900−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −160,499−100.0% | Sold out |
| Jain Global LLC | 0 | $0 | 0.00% | −154,800−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −152,616−100.0% | Sold out |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −130,020−100.0% | Sold out |
| Bridgewater Advisors Inc. | 0 | $0 | 0.00% | −82,209−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −122,780−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | −108,806−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −106,800−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −68,734−100.0% | Sold out |
| Diametric Capital, LP | 0 | $0 | 0.00% | −67,841−100.0% | Sold out |
| EntryPoint Capital, LLC | 0 | $0 | 0.00% | −48,498−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −40,246−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −37,430−100.0% | Sold out |
| KWB Wealth | 0 | $0 | 0.00% | −40,640−100.0% | Sold out |
| Oppenheimer & Co Inc | 0 | $0 | 0.00% | −23,500−100.0% | Sold out |
| Cambridge Investment Research Advisors, Inc. | 0 | $0 | 0.00% | −21,505−100.0% | Sold out |
| Quantessence Capital LLC | 0 | $0 | 0.00% | −18,581−100.0% | Sold out |
| CTC Alternative Strategies, Ltd. | 0 | $0 | 0.00% | −17,544−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −17,173−100.0% | Sold out |
| Chemistry Wealth Management LLC | 0 | $0 | 0.00% | −12,000−100.0% | Sold out |
| Fortress Wealth Group, LLC | 0 | $0 | 0.00% | −11,350−100.0% | Sold out |
| Talisman Wealth Advisors LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −3,242−100.0% | Sold out |
| EverSource Wealth Advisors, LLC | 0 | $0 | 0.00% | −48−100.0% | Sold out |
| True Wealth Design, LLC | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| CWM, LLC | – | – | – | – | Not filed |