Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 149
- +13 vs. Q1 2026
- Shares held
- 364.6M
- +41.2M (+12.8%) vs. Q1 2026
- Total value
- $875.1M
- +$370.5M (+73.4%) vs. Q1 2026
- New holders
- 43
- 37 more added
- Sold out
- 30
- 36 more reduced
1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 81 | $0 | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 2 | $5 | 0.00% | −253−99.2% | Reduced |
| Blume Capital Management, Inc. | 5 | $12 | 0.00% | +5 | New |
| HM Payson & Co | 37 | $89 | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 41 | $98 | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 100 | $240 | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 100 | $240 | 0.00% | +100 | New |
| Syntax Research, Inc. | 142 | $341 | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 157 | $377 | 0.00% | −196−55.5% | Reduced |
| Advisor Group Holdings, Inc. | 163 | $390 | 0.00% | −500−75.4% | Reduced |
| Parallel Advisors, LLC | 247 | $593 | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 263 | $632 | 0.00% | +263 | New |
| Rockefeller Capital Management L.P. | 300 | $720 | 0.00% | −35−10.4% | Reduced |
| Jones Financial Companies LLLP | 356 | $908 | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 400 | $960 | 0.00% | −100−20.0% | Reduced |
| Northwestern Mutual Wealth Management Co | 500 | $1.20K | 0.00% | −3−0.6% | Reduced |
| Basecamp Wealth Advisors LLC | 691 | $1.66K | 0.00% | 00.0% | Unchanged |
| Fortitude Family Office, LLC | 706 | $1.69K | 0.00% | 00.0% | Unchanged |
| Aster Capital Management (DIFC) Ltd | 743 | $1.78K | 0.00% | +743 | New |
| Avion Wealth | 1,115 | $2.00K | 0.00% | −218−16.4% | Reduced |
| Sterling Capital Management LLC | 874 | $2.10K | 0.00% | +874 | New |
| Massmutual Trust Co FSB | 957 | $2.30K | 0.00% | +957 | New |
| Cassaday & Co Wealth Management LLC | 1,000 | $2.40K | 0.00% | 00.0% | Unchanged |
| Global Retirement Partners, LLC | 1,000 | $2.40K | 0.00% | +1,000 | New |
| Rialto Wealth Management, LLC | 1,313 | $3.15K | 0.00% | 00.0% | Unchanged |
| UMA Financial Services, Inc. | 1,412 | $3.39K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 1,461 | $3.51K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 2,592 | $6.22K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 3,427 | $8.22K | 0.00% | +3,427 | New |
| Simplex Trading, LLC | 8,540 | $20.5K | 0.00% | +8,540 | New |
| NBT Bank N A | 10,000 | $24.0K | 0.00% | 00.0% | Unchanged |
| Berger Financial Group, Inc | 10,000 | $24.0K | 0.00% | 00.0% | Unchanged |
| Cetera Investment Advisers | 10,524 | $25.3K | 0.00% | −2,109−16.7% | Reduced |
| Perennial Investment Advisors, LLC | 10,990 | $26.4K | 0.00% | 00.0% | Unchanged |
| Wealth Enhancement Advisory Services, LLC | 12,139 | $26.9K | 0.00% | −249−2.0% | Reduced |
| Mariner, LLC | 11,239 | $27.0K | 0.00% | +167+1.5% | Added |
| Apollon Wealth Management, LLC | 11,378 | $27.3K | 0.00% | +11,378 | New |
| Squarepoint Ops LLC | 11,741 | $28.2K | 0.00% | +11,741 | New |
| HBK Sorce Advisory LLC | 11,786 | $28.9K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 12,650 | $30.0K | 0.00% | +11,099+715.6% | Added |
| CIBC Asset Management Inc | 13,102 | $31.4K | 0.00% | −26,418−66.8% | Reduced |
| Gotham Asset Management, LLC | 13,627 | $32.7K | 0.00% | +13,627 | New |
| CIBC Bancorp USA Inc. | 13,740 | $33.0K | 0.00% | −1,786,260−99.2% | Reduced |
| Truist Financial Corp | 14,000 | $33.6K | 0.00% | 00.0% | Unchanged |
| Callan Family Office, LLC | 14,090 | $33.8K | 0.00% | 00.0% | Unchanged |
| Captrust Financial Advisors | 15,321 | $36.8K | 0.00% | −129−0.8% | Reduced |
| Credit Agricole S A | 18,975 | $45.5K | 0.00% | 00.0% | Unchanged |
| Principal Financial Group Inc | 19,034 | $45.7K | 0.00% | +19,034 | New |
| SBI Securities Co., Ltd. | 19,205 | $46.1K | 0.00% | +15,124+370.6% | Added |
| Tower Research Capital LLC (TRC) | 19,486 | $46.8K | 0.00% | +19,486 | New |
| Russell Investments Group, Ltd. | 19,902 | $47.8K | 0.00% | +19,902 | New |
| Wedbush Securities Inc | 20,000 | $48.0K | 0.00% | −20,850−51.0% | Reduced |
| Tiaa-Cref Individual & Institutional Services, LLC | 20,000 | $48.0K | 0.00% | 00.0% | Unchanged |
| Diker Management LLC | 20,000 | $48.0K | 0.04% | 00.0% | Unchanged |
| Invera Wealth Advisors, LLC | 20,000 | $48.0K | 0.03% | 00.0% | Unchanged |
| Quadrature Capital Ltd | 21,998 | $52.8K | 0.00% | −88,381−80.1% | Reduced |
| D. E. Shaw & Co., Inc. | 22,200 | $53.3K | 0.00% | +22,200 | New |
| Ameritas Investment Partners, Inc. | 22,986 | $55.2K | 0.00% | +22,986 | New |
| Graham Capital Management, L.P. | 23,541 | $56.5K | 0.00% | −10,486−30.8% | Reduced |
| Xponance, Inc. | 23,763 | $57.0K | 0.00% | +23,763 | New |
| Legal & General Group Plc | 24,185 | $58.0K | 0.00% | +24,185 | New |
| Victory Capital Management Inc | 24,223 | $58.1K | 0.00% | +1,544+6.8% | Added |
| Security National Bank of Sioux City Iowa | 26,650 | $64.0K | 0.03% | 00.0% | Unchanged |
| Pinnacle Associates Ltd | 29,015 | $69.6K | 0.00% | 00.0% | Unchanged |
| Pathstone Holdings, LLC | 29,969 | $71.9K | 0.00% | +195+0.7% | Added |
| Leonteq Securities AG | 30,000 | $72.0K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 32,588 | $78.2K | 0.00% | +32,588 | New |
| Rafferty Asset Management, LLC | 34,090 | $81.8K | 0.00% | +34,090 | New |
| BNP Paribas Arbitrage, SA | 37,780 | $90.7K | 0.00% | +20,230+115.3% | Added |
| Bank of Montreal | 40,000 | $96.0K | 0.00% | −30,000−42.9% | Reduced |
| LMR Partners LLP | 41,091 | $98.6K | 0.00% | +17,786+76.3% | Added |
| Intech Investment Management LLC | 42,491 | $102.0K | 0.00% | +42,491 | New |
| Winton Group Ltd | 43,200 | $103.7K | 0.00% | +17,700+69.4% | Added |
| Alliancebernstein L.P. | 67,800 | $105.8K | 0.00% | +67,800 | New |
| Boothbay Fund Management, LLC | 44,315 | $106.4K | 0.00% | 00.0% | Unchanged |
| Axq Capital, LP | 45,727 | $109.7K | 0.01% | +25,577+126.9% | Added |
| Voya Investment Management LLC | 47,771 | $114.7K | 0.00% | +47,771 | New |
| Profund Advisors LLC | 48,586 | $116.6K | 0.00% | +48,586 | New |
| Scotia Capital Inc. | 48,871 | $117.3K | 0.00% | −110,960−69.4% | Reduced |
| Schonfeld Strategic Advisors LLC | 49,435 | $118.6K | 0.00% | −25,675−34.2% | Reduced |
| Fortis Group Advisors, LLC | 50,000 | $120.0K | 0.02% | 00.0% | Unchanged |
| JustInvest LLC | 54,334 | $130.4K | 0.00% | −631−1.1% | Reduced |
| R Squared Ltd | 54,985 | $132.0K | 0.07% | −12,541−18.6% | Reduced |
| Straight Path Wealth Management | 62,666 | $150.4K | 0.04% | 00.0% | Unchanged |
| SEI Investments Co | 63,937 | $153.4K | 0.00% | +63,937 | New |
| Two Sigma Securities, LLC | 66,375 | $159.3K | 0.01% | +66,375 | New |
| New York State Common Retirement Fund | 68,400 | $164.2K | 0.00% | +68,400 | New |
| Manufacturers Life Insurance Company, The | 69,747 | $167.4K | 0.00% | +69,747 | New |
| Prudential Financial Inc | 71,345 | $171.2K | 0.00% | +37,545+111.1% | Added |
| University of Texas/Texas Am Investment Managment Co | 71,427 | $171.4K | 0.02% | +35,713+100.0% | Added |
| Police & Firemen's Retirement System of New Jersey | 73,402 | $176.2K | 0.00% | +73,402 | New |
| AQR Capital Management LLC | 75,230 | $180.6K | 0.00% | −21,004−21.8% | Reduced |
| Vanguard Global Advisers, LLC | 77,946 | $187.1K | 0.00% | −15,695−16.8% | Reduced |
| LPL Financial LLC | 84,916 | $203.8K | 0.00% | +15,133+21.7% | Added |
| Bank of Nova Scotia | 86,607 | $207.9K | 0.00% | +12,900+17.5% | Added |
| Algert Global LLC | 92,150 | $221.2K | 0.00% | +92,150 | New |
| Cerity Partners LLC | 98,400 | $236.2K | 0.00% | −12,058−10.9% | Reduced |
| Cornerstone Investment Partners, LLC | 113,739 | $273.0K | 0.01% | +113,739 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 114,114 | $273.9K | 0.00% | +114,114 | New |
| State of Wyoming | 119,090 | $285.8K | 0.03% | +108,311+1,004.8% | Added |