Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 149
- +13 vs. Q1 2026
- Shares held
- 364.6M
- +41.2M (+12.8%) vs. Q1 2026
- Total value
- $875.1M
- +$370.5M (+73.4%) vs. Q1 2026
- New holders
- 43
- 37 more added
- Sold out
- 30
- 36 more reduced
1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| JPMorgan Chase & Co | 109,839 | $290.0K | 0.00% | +109,839 | New |
| Panagora Asset Management Inc | 132,042 | $316.9K | 0.00% | +132,042 | New |
| Morgan Stanley | 132,902 | $319.0K | 0.00% | −86,960−39.6% | Reduced |
| MetLife Investment Management | 146,410 | $351.4K | 0.00% | +146,410 | New |
| Quarry LP | 156,186 | $374.8K | 0.06% | +46,186+42.0% | Added |
| Ikarian Capital, LLC | 164,674 | $395.2K | 0.06% | 00.0% | Unchanged |
| Headlands Technologies LLC | 167,198 | $401.3K | 0.04% | −24,124−12.6% | Reduced |
| Virtus Investment Advisers, Inc. | 170,415 | $409.0K | 0.10% | +170,415 | New |
| Group One Trading, L.P. | 175,013 | $420.0K | 0.01% | −9,993−5.4% | Reduced |
| Citigroup Inc | 175,205 | $420.5K | 0.00% | +8,807+5.3% | Added |
| Wellington Management Group LLP | 179,700 | $431.3K | 0.00% | +179,700 | New |
| Price T Rowe Associates Inc | 204,391 | $491.0K | 0.00% | +204,391 | New |
| Wells Fargo & Company | 230,470 | $553.1K | 0.00% | +222,710+2,870.0% | Added |
| Deutsche Bank AG | 247,528 | $594.1K | 0.00% | +247,528 | New |
| Rhumbline Advisers | 256,885 | $616.5K | 0.00% | +256,885 | Added |
| Canada Pension Plan Investment Board | 257,900 | $619.0K | 0.00% | +257,900 | New |
| Janney Montgomery Scott LLC | 295,548 | $709.0K | 0.00% | +295,548 | New |
| XTX Topco Ltd | 357,877 | $858.9K | 0.01% | +43,263+13.8% | Added |
| Barclays PLC | 387,483 | $930.0K | 0.00% | +281,996+267.3% | Added |
| Gsa Capital Partners LLP | 397,219 | $953.0K | 0.06% | −532,870−57.3% | Reduced |
| Bank of America Corp | 421,299 | $1.01M | 0.00% | −104,804−19.9% | Reduced |
| Compagnie Lombard Odier SCmA | 480,000 | $1.15M | 0.01% | −30,000−5.9% | Reduced |
| Goldman Sachs Group Inc | 485,546 | $1.17M | 0.00% | −584,971−54.6% | Reduced |
| Invesco Ltd. | 508,071 | $1.22M | 0.00% | −4,355−0.8% | Reduced |
| Bank of New York Mellon Corp | 568,706 | $1.36M | 0.00% | +541,247+1,971.1% | Added |
| Nuveen, LLC | 586,664 | $1.41M | 0.00% | +586,664 | New |
| Two Sigma Investments, LP | 643,444 | $1.54M | 0.00% | −556,188−46.4% | Reduced |
| UBS Group AG | 684,713 | $1.64M | 0.00% | −1,798,469−72.4% | Reduced |
| Acadian Asset Management LLC | 696,617 | $1.67M | 0.00% | +251,329+56.4% | Added |
| Susquehanna International Group, LLP | 696,776 | $1.67M | 0.00% | −1,424,388−67.2% | Reduced |
| ADAR1 Capital Management, LLC | 750,000 | $1.80M | 0.08% | 00.0% | Unchanged |
| Mackenzie Financial Corp | 963,354 | $2.31M | 0.00% | +190,677+24.7% | Added |
| Renaissance Technologies LLC | 1,127,000 | $2.70M | 0.00% | −473,500−29.6% | Reduced |
| Millennium Management LLC | 1,134,229 | $2.72M | 0.00% | −3,810,502−77.1% | Reduced |
| Ishara Investments LP | 1,271,000 | $3.05M | 2.28% | +369,000+40.9% | Added |
| Citadel Advisors LLC | 1,601,182 | $3.84M | 0.00% | +506,281+46.2% | Added |
| Vanguard Fiduciary Trust Co | 1,634,571 | $3.92M | 0.00% | +302,287+22.7% | Added |
| Charles Schwab Investment Management Inc | 1,956,775 | $4.70M | 0.00% | +645,477+49.2% | Added |
| Northern Trust Corp | 1,968,619 | $4.72M | 0.00% | +1,473,953+298.0% | Added |
| Vanguard Portfolio Management LLC | 2,357,749 | $5.66M | 0.00% | +1,811,149+331.3% | Added |
| State Street Corp | 4,917,769 | $11.8M | 0.00% | +3,953,731+410.1% | Added |
| Geode Capital Management, LLC | 6,244,372 | $15.0M | 0.00% | +3,075,261+97.0% | Added |
| Point72 Asset Management, L.P. | 8,251,325 | $19.8M | 0.03% | +436,719+5.6% | Added |
| Vanguard Capital Management LLC | 9,901,208 | $23.8M | 0.00% | +382,041+4.0% | Added |
| BlackRock, Inc. | 17,348,741 | $41.6M | 0.00% | +14,026,522+422.2% | Added |
| Sessa Capital IM, L.P. | 18,960,836 | $45.5M | 0.79% | +1,047,875+5.8% | Added |
| Siren, L.L.C. | 44,303,518 | $106.3M | 2.16% | 00.0% | Unchanged |
| FMR LLC | 51,782,045 | $124.3M | 0.01% | +6,725,707+14.9% | Added |
| Artal Group S.A. | 175,156,062 | $420.4M | 45.15% | +20,421,735+13.2% | Added |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −2,665,938−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −2,376,304−100.0% | Sold out |
| Hennion & Walsh Asset Management, Inc. | 0 | $0 | 0.00% | −848,138−100.0% | Sold out |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −399,700−100.0% | Sold out |
| Catalyst Funds Management Pty Ltd | 0 | $0 | 0.00% | −207,900−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −160,499−100.0% | Sold out |
| Jain Global LLC | 0 | $0 | 0.00% | −154,800−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −152,616−100.0% | Sold out |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −130,020−100.0% | Sold out |
| Bridgewater Advisors Inc. | 0 | $0 | 0.00% | −82,209−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −122,780−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | −108,806−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −106,800−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −68,734−100.0% | Sold out |
| Diametric Capital, LP | 0 | $0 | 0.00% | −67,841−100.0% | Sold out |
| EntryPoint Capital, LLC | 0 | $0 | 0.00% | −48,498−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −40,246−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −37,430−100.0% | Sold out |
| KWB Wealth | 0 | $0 | 0.00% | −40,640−100.0% | Sold out |
| Oppenheimer & Co Inc | 0 | $0 | 0.00% | −23,500−100.0% | Sold out |
| Cambridge Investment Research Advisors, Inc. | 0 | $0 | 0.00% | −21,505−100.0% | Sold out |
| Quantessence Capital LLC | 0 | $0 | 0.00% | −18,581−100.0% | Sold out |
| CTC Alternative Strategies, Ltd. | 0 | $0 | 0.00% | −17,544−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −17,173−100.0% | Sold out |
| Chemistry Wealth Management LLC | 0 | $0 | 0.00% | −12,000−100.0% | Sold out |
| Fortress Wealth Group, LLC | 0 | $0 | 0.00% | −11,350−100.0% | Sold out |
| Talisman Wealth Advisors LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −3,242−100.0% | Sold out |
| EverSource Wealth Advisors, LLC | 0 | $0 | 0.00% | −48−100.0% | Sold out |
| True Wealth Design, LLC | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| CWM, LLC | – | – | – | – | Not filed |