Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 123
- −4 vs. Q1 2025
- Shares held
- 256.3M
- −9.49M (−3.6%) vs. Q1 2025
- Total value
- $242.9M
- +$120.5M (+98.4%) vs. Q1 2025
- New holders
- 29
- 31 more added
- Sold out
- 33
- 36 more reduced
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Northern Trust Corp | 416,372 | $393.8K | 0.00% | −693,515−62.5% | Reduced |
| Invesco Ltd. | 420,700 | $397.9K | 0.00% | +134,941+47.2% | Added |
| Wellington Management Group LLP | 486,674 | $460.2K | 0.00% | +486,674 | New |
| HRT Financial LP | 488,468 | $461.0K | 0.00% | +488,468 | New |
| Monaco Asset Management SAM | 531,600 | $502.7K | 0.19% | −202,548−27.6% | Reduced |
| Susquehanna International Group, LLP | 755,652 | $714.6K | 0.00% | −195,483−20.6% | Reduced |
| Royal Bank of Canada | 774,474 | $732.0K | 0.00% | +771,315+24,416.4% | Added |
| Hennion & Walsh Asset Management, Inc. | 793,400 | $750.3K | 0.03% | −36,654−4.4% | Reduced |
| Jane Street Group, LLC | 804,667 | $761.0K | 0.00% | +804,667 | New |
| State Street Corp | 818,621 | $774.2K | 0.00% | −1,788,953−68.6% | Reduced |
| Charles Schwab Investment Management Inc | 883,227 | $835.3K | 0.00% | −267,544−23.2% | Reduced |
| AQR Capital Management LLC | 1,402,210 | $1.33M | 0.00% | +228,985+19.5% | Added |
| Millennium Management LLC | 1,643,264 | $1.55M | 0.00% | +1,643,264 | New |
| Geode Capital Management, LLC | 2,377,694 | $2.25M | 0.00% | −1,311,577−35.6% | Reduced |
| CIBC Private Wealth Group, LLC | 2,450,400 | $2.32M | 0.00% | +210,400+9.4% | Added |
| Gsa Capital Partners LLP | 2,830,659 | $2.68M | 0.19% | +2,023,167+250.5% | Added |
| Sessa Capital IM, L.P. | 3,000,000 | $2.84M | 0.09% | +3,000,000 | New |
| BlackRock, Inc. | 3,354,669 | $3.17M | 0.00% | −6,658,338−66.5% | Reduced |
| Schonfeld Strategic Advisors LLC | 4,576,152 | $4.33M | 0.03% | −3,636,841−44.3% | Reduced |
| Vanguard Group Inc | 8,851,036 | $8.37M | 0.00% | −706,139−7.4% | Reduced |
| FMR LLC | 38,137,535 | $36.1M | 0.00% | +3,594,338+10.4% | Added |
| Siren, L.L.C. | 38,918,903 | $36.8M | 1.90% | 00.0% | Unchanged |
| Artal Group S.A. | 136,180,481 | $129.4M | 13.91% | 00.0% | Unchanged |
| Rhumbline Advisers | 0 | $0 | 0.00% | −137,230−100.0% | Sold out |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −1,150,268−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −573,688−100.0% | Sold out |
| BBR Partners, LLC | 0 | $0 | 0.00% | −570,000−100.0% | Sold out |
| Nantahala Capital Management, LLC | 0 | $0 | 0.00% | −460,850−100.0% | Sold out |
| Virtus Investment Advisers, Inc. | 0 | $0 | 0.00% | −436,672−100.0% | Sold out |
| Alliancebernstein L.P. | 0 | $0 | 0.00% | −246,121−100.0% | Sold out |
| Deutsche Bank AG | 0 | $0 | 0.00% | −94,394−100.0% | Sold out |
| Price T Rowe Associates Inc | 0 | $0 | 0.00% | −92,248−100.0% | Sold out |
| Intech Investment Management LLC | 0 | $0 | 0.00% | −73,853−100.0% | Sold out |
| Mirae Asset Global ETFs Holdings Ltd. | 0 | $0 | 0.00% | −68,683−100.0% | Sold out |
| Corebridge Financial, Inc. | 0 | $0 | 0.00% | −56,248−100.0% | Sold out |
| New York State Common Retirement Fund | 0 | $0 | 0.00% | −33,702−100.0% | Sold out |
| Police & Firemen's Retirement System of New Jersey | 0 | $0 | 0.00% | −29,715−100.0% | Sold out |
| CIBC World Markets Corp | 0 | $0 | 0.00% | −25,477−100.0% | Sold out |
| SIH Partners, LLLP | 0 | $0 | 0.00% | −23,712−100.0% | Sold out |
| Simplicity Wealth,LLC | 0 | $0 | 0.00% | −20,447−100.0% | Sold out |
| Ethic Inc. | 0 | $0 | 0.00% | −17,259−100.0% | Sold out |
| HSBC Holdings PLC | 0 | $0 | 0.00% | −13,415−100.0% | Sold out |
| Voya Investment Management LLC | 0 | $0 | 0.00% | −13,922−100.0% | Sold out |
| Legal & General Group Plc | 0 | $0 | 0.00% | −11,466−100.0% | Sold out |
| Chaney Capital Management, Inc. | 0 | $0 | 0.00% | −11,167−100.0% | Sold out |
| Unique Wealth Strategies, LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Ameritas Investment Partners, Inc. | 0 | $0 | 0.00% | −8,867−100.0% | Sold out |
| California State Teachers Retirement System | 0 | $0 | 0.00% | −8,319−100.0% | Sold out |
| Amalgamated Bank | 0 | $0 | 0.00% | −2,409−100.0% | Sold out |
| Coldstream Capital Management Inc | 0 | $0 | 0.00% | −1,388−100.0% | Sold out |
| Sterling Capital Management LLC | 0 | $0 | 0.00% | −1,280−100.0% | Sold out |
| US Bancorp | 0 | $0 | 0.00% | −1,082−100.0% | Sold out |
| Pinney & Scofield, Inc. | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −406−100.0% | Sold out |
| SJS Investment Consulting Inc. | 0 | $0 | 0.00% | −400−100.0% | Sold out |
| GWM Advisors LLC | 0 | $0 | 0.00% | −5−100.0% | Sold out |