Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 123
- −4 vs. Q1 2025
- Shares held
- 256.3M
- −9.49M (−3.6%) vs. Q1 2025
- Total value
- $242.9M
- +$120.5M (+98.4%) vs. Q1 2025
- New holders
- 29
- 31 more added
- Sold out
- 33
- 36 more reduced
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 81 | $0 | 0.00% | 00.0% | Unchanged |
| IFP Advisors, Inc | 1 | $1 | 0.00% | +1 | New |
| CBIZ Investment Advisory Services, LLC | 71 | $67 | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 100 | $95 | 0.00% | 00.0% | Unchanged |
| Comerica Bank | 122 | $115 | 0.00% | 00.0% | Unchanged |
| Syntax Research, Inc. | 142 | $135 | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 500 | $473 | 0.00% | 00.0% | Unchanged |
| Fortitude Family Office, LLC | 706 | $668 | 0.00% | +706 | New |
| Advisor Group Holdings, Inc. | 742 | $697 | 0.00% | −200−21.2% | Reduced |
| True Wealth Design, LLC | 743 | $703 | 0.00% | +124+20.0% | Added |
| Global Retirement Partners, LLC | 1,000 | $946 | 0.00% | +1,000 | New |
| Farther Finance Advisors, LLC | 1,002 | $948 | 0.00% | +1,000+50,000.0% | Added |
| Daiwa Securities Group Inc. | 1,369 | $1.00K | 0.00% | 00.0% | Unchanged |
| Avion Wealth | 1,333 | $1.00K | 0.00% | +199+17.5% | Added |
| EverSource Wealth Advisors, LLC | 1,163 | $1.10K | 0.00% | +233+25.1% | Added |
| Rialto Wealth Management, LLC | 1,313 | $1.24K | 0.00% | 00.0% | Unchanged |
| UMA Financial Services, Inc. | 1,412 | $1.34K | 0.00% | +1,412 | New |
| The PNC Financial Services Group, Inc. | 1,461 | $1.38K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 2,042 | $1.67K | 0.00% | 00.0% | Unchanged |
| Quintet Private Bank (Europe) S.A. | 1,928 | $1.82K | 0.00% | 00.0% | Unchanged |
| Raymond James Financial Inc | 2,076 | $1.96K | 0.00% | −9,836−82.6% | Reduced |
| Essential Partners LLC | 2,134 | $2.02K | 0.00% | +2,134 | New |
| Nisa Investment Advisors, LLC | 2,592 | $2.45K | 0.00% | +1,992+332.0% | Added |
| Optiver Holding B.V. | 3,035 | $2.87K | 0.00% | +1,192+64.7% | Added |
| Golden State Wealth Management, LLC | 3,700 | $3.50K | 0.00% | 00.0% | Unchanged |
| Vermillion & White Wealth Management Group, LLC | 6,500 | $6.15K | 0.00% | +6,500 | New |
| Point72 (DIFC) Ltd | 6,982 | $6.60K | 0.00% | −6,345−47.6% | Reduced |
| BNP Paribas Arbitrage, SA | 8,703 | $8.23K | 0.00% | −80,411−90.2% | Reduced |
| NBT Bank N A | 10,000 | $9.46K | 0.00% | +10,000 | New |
| Berger Financial Group, Inc | 10,929 | $10.3K | 0.00% | 00.0% | Unchanged |
| Perennial Investment Advisors, LLC | 10,990 | $10.4K | 0.00% | +10,990 | New |
| North Star Asset Management Inc | 11,500 | $10.9K | 0.00% | 00.0% | Unchanged |
| Avantax Advisory Services, Inc. | 11,724 | $11.1K | 0.00% | 00.0% | Unchanged |
| HBK Sorce Advisory LLC | 11,786 | $11.1K | 0.00% | +11,786 | New |
| Chemistry Wealth Management LLC | 12,000 | $11.3K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 12,690 | $12.0K | 0.00% | −15,417−54.9% | Reduced |
| ExodusPoint Capital Management, LP | 12,241 | $12.0K | 0.00% | +12,241 | New |
| ProShare Advisors LLC | 13,561 | $12.8K | 0.00% | −27,601−67.1% | Reduced |
| SG Americas Securities, LLC | 13,814 | $13.0K | 0.00% | −54,198−79.7% | Reduced |
| Buckingham Strategic Partners | 13,746 | $13.0K | 0.00% | +1,650+13.6% | Added |
| Truist Financial Corp | 14,000 | $13.2K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 14,029 | $13.3K | 0.00% | +1,933+16.0% | Added |
| HighTower Advisors, LLC | 14,910 | $14.1K | 0.00% | +14,910 | New |
| Jump Financial, LLC | 15,993 | $15.1K | 0.00% | +15,993 | New |
| Integrated Wealth Concepts LLC | 16,210 | $15.3K | 0.00% | +16,210 | New |
| Merit Financial Group, LLC | 16,699 | $15.8K | 0.00% | +1,207+7.8% | Added |
| Bank of New York Mellon Corp | 19,124 | $18.1K | 0.00% | −290,995−93.8% | Reduced |
| SBI Securities Co., Ltd. | 19,237 | $18.2K | 0.00% | +15,917+479.4% | Added |
| KWB Wealth | 40,640 | $18.7K | 0.00% | 00.0% | Unchanged |
| Invera Wealth Advisors, LLC | 20,000 | $18.9K | 0.01% | 00.0% | Unchanged |
| Tiaa Trust, National Association | 20,000 | $18.9K | 0.00% | 00.0% | Unchanged |
| Victory Capital Management Inc | 21,115 | $20.0K | 0.00% | −518−2.4% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 21,500 | $20.0K | 0.00% | −575−2.6% | Reduced |
| Steward Partners Investment Advisory, LLC | 21,423 | $20.3K | 0.00% | +100+0.5% | Added |
| Oppenheimer & Co Inc | 23,500 | $22.2K | 0.00% | +3,400+16.9% | Added |
| D. E. Shaw & Co., Inc. | 23,723 | $22.4K | 0.00% | +23,723 | New |
| JPMorgan Chase & Co | 24,684 | $23.3K | 0.00% | −63,515−72.0% | Reduced |
| Wells Fargo & Company | 26,423 | $25.0K | 0.00% | −37,505−58.7% | Reduced |
| Hudson Bay Capital Management LP | 27,010 | $25.5K | 0.00% | +27,010 | New |
| R Squared Ltd | 29,559 | $28.0K | 0.02% | +29,559 | New |
| Pathstone Holdings, LLC | 30,041 | $28.4K | 0.00% | −1,356−4.3% | Reduced |
| Bank of America Corp | 32,097 | $30.3K | 0.00% | −64,290−66.7% | Reduced |
| Barclays PLC | 32,270 | $30.5K | 0.00% | −113,801−77.9% | Reduced |
| Captrust Financial Advisors | 35,582 | $33.6K | 0.00% | +2,398+7.2% | Added |
| University of Texas/Texas Am Investment Managment Co | 35,714 | $33.8K | 0.01% | 00.0% | Unchanged |
| Pallas Capital Advisors LLC | 36,765 | $34.8K | 0.00% | +557+1.5% | Added |
| Wedbush Securities Inc | 40,850 | $39.0K | 0.00% | 00.0% | Unchanged |
| Two Sigma Securities, LLC | 42,405 | $40.1K | 0.00% | +42,405 | New |
| Citigroup Inc | 48,544 | $45.9K | 0.00% | −48,424−49.9% | Reduced |
| Pinnacle Associates Ltd | 50,815 | $48.1K | 0.00% | −3,365−6.2% | Reduced |
| Simplex Trading, LLC | 52,680 | $49.0K | 0.00% | −122,302−69.9% | Reduced |
| Catalyst Funds Management Pty Ltd | 53,700 | $50.8K | 0.01% | +53,700 | New |
| Boothbay Fund Management, LLC | 56,120 | $53.1K | 0.00% | −398,771−87.7% | Reduced |
| Scientech Research LLC | 57,862 | $54.7K | 0.01% | +57,862 | New |
| Straight Path Wealth Management | 62,666 | $59.3K | 0.02% | 00.0% | Unchanged |
| JustInvest LLC | 65,330 | $61.8K | 0.00% | +28,594+77.8% | Added |
| Fortis Group Advisors, LLC | 57,800 | $61.8K | 0.01% | +20,000+52.9% | Added |
| XTX Topco Ltd | 66,276 | $62.7K | 0.00% | +53,805+431.4% | Added |
| Point72 Asia (Singapore) Pte. Ltd. | 70,045 | $66.2K | 0.01% | −101,102−59.1% | Reduced |
| Wealth Enhancement Advisory Services, LLC | 74,454 | $67.1K | 0.00% | +5,247+7.6% | Added |
| China Universal Asset Management Co., Ltd. | 72,943 | $69.0K | 0.01% | +434+0.6% | Added |
| Quantessence Capital LLC | 84,098 | $79.5K | 0.02% | +84,098 | New |
| Commonwealth Equity Services, LLC | 90,864 | $86.0K | 0.00% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 95,617 | $90.4K | 0.00% | −99,792−51.1% | Reduced |
| Bank of Montreal | 100,000 | $94.6K | 0.00% | 00.0% | Unchanged |
| LPL Financial LLC | 104,433 | $98.8K | 0.00% | +33,476+47.2% | Added |
| CWM, LLC | 109,330 | $103.0K | 0.00% | +3,826+3.6% | Added |
| Aster Capital Management (DIFC) Ltd | 130,452 | $123.4K | 0.03% | +130,452 | New |
| Morgan Stanley | 131,393 | $124.3K | 0.00% | −510,236−79.5% | Reduced |
| Virtu Financial LLC | 146,805 | $139.0K | 0.01% | +146,805 | New |
| Jain Global LLC | 151,813 | $143.6K | 0.00% | +151,813 | New |
| Cubist Systematic Strategies, LLC | 158,204 | $149.6K | 0.00% | +144,407+1,046.7% | Added |
| Ikarian Capital, LLC | 176,479 | $166.9K | 0.06% | −1,241,473−87.6% | Reduced |
| Ieq Capital, LLC | 192,101 | $181.7K | 0.00% | +14,799+8.3% | Added |
| Cerity Partners LLC | 206,279 | $195.1K | 0.00% | +35,892+21.1% | Added |
| Goldman Sachs Group Inc | 325,746 | $308.1K | 0.00% | −29,406−8.3% | Reduced |
| Compagnie Lombard Odier SCmA | 330,000 | $312.1K | 0.00% | +220,000+200.0% | Added |
| Group One Trading, L.P. | 346,752 | $327.9K | 0.01% | −19,054−5.2% | Reduced |
| UBS Group AG | 400,732 | $379.1K | 0.00% | −1,694,608−80.9% | Reduced |
| Two Sigma Investments, LP | 403,922 | $382.0K | 0.00% | +403,922 | New |