Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 127
- +2 vs. Q4 2024
- Shares held
- 265.8M
- −30.8M (−10.4%) vs. Q4 2024
- Total value
- $122.5M
- −$96.9M (−44.2%) vs. Q4 2024
- New holders
- 31
- 34 more added
- Sold out
- 29
- 32 more reduced
2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Goldman Sachs Group Inc | 355,152 | $163.7K | 0.00% | −185,055−34.3% | Reduced |
| Group One Trading, L.P. | 365,806 | $168.6K | 0.01% | +51,402+16.3% | Added |
| Virtus Investment Advisers, Inc. | 436,672 | $201.2K | 0.05% | +436,672 | New |
| Boothbay Fund Management, LLC | 454,891 | $209.6K | 0.01% | −25,931−5.4% | Reduced |
| Nantahala Capital Management, LLC | 460,850 | $212.4K | 0.02% | −6,143,300−93.0% | Reduced |
| BBR Partners, LLC | 570,000 | $262.7K | 0.02% | +100,000+21.3% | Added |
| Acadian Asset Management LLC | 573,688 | $263.0K | 0.00% | +573,688 | New |
| Morgan Stanley | 641,629 | $295.7K | 0.00% | +115,479+21.9% | Added |
| Monaco Asset Management SAM | 734,148 | $338.3K | 0.17% | +734,148 | New |
| Gsa Capital Partners LLP | 807,492 | $372.0K | 0.03% | +807,492 | New |
| Hennion & Walsh Asset Management, Inc. | 830,054 | $382.5K | 0.02% | −33,201−3.8% | Reduced |
| Susquehanna International Group, LLP | 951,135 | $438.3K | 0.00% | +400,244+72.7% | Added |
| Northern Trust Corp | 1,109,887 | $511.4K | 0.00% | −198,764−15.2% | Reduced |
| Tang Capital Management LLC | 1,150,268 | $530.0K | 0.03% | +300,000+35.3% | Added |
| Charles Schwab Investment Management Inc | 1,150,771 | $530.3K | 0.00% | −40,320−3.4% | Reduced |
| AQR Capital Management LLC | 1,173,225 | $540.6K | 0.00% | +1,173,225 | New |
| Ikarian Capital, LLC | 1,417,952 | $653.4K | 0.21% | −132,048−8.5% | Reduced |
| UBS Group AG | 2,095,340 | $966.0K | 0.00% | +1,409,223+205.4% | Added |
| CIBC Private Wealth Group, LLC | 2,240,000 | $1.12M | 0.00% | +2,240,000 | New |
| State Street Corp | 2,607,574 | $1.20M | 0.00% | −110,674−4.1% | Reduced |
| Geode Capital Management, LLC | 3,689,271 | $1.70M | 0.00% | +168,016+4.8% | Added |
| Schonfeld Strategic Advisors LLC | 8,212,993 | $3.78M | 0.03% | +654,372+8.7% | Added |
| Vanguard Group Inc | 9,557,175 | $4.41M | 0.00% | −324,553−3.3% | Reduced |
| BlackRock, Inc. | 10,013,007 | $4.61M | 0.00% | −320,151−3.1% | Reduced |
| FMR LLC | 34,543,197 | $15.9M | 0.00% | −17,427,258−33.5% | Reduced |
| Siren, L.L.C. | 38,918,903 | $17.9M | 1.01% | 00.0% | Unchanged |
| Artal Group S.A. | 136,180,481 | $62.6M | 7.08% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −8,988,421−100.0% | Sold out |
| NEA Management Company, LLC | 0 | $0 | 0.00% | −2,382,286−100.0% | Sold out |
| Wellington Management Group LLP | 0 | $0 | 0.00% | −747,996−100.0% | Sold out |
| Swiss National Bank | 0 | $0 | 0.00% | −426,600−100.0% | Sold out |
| Virtus ETF Advisers LLC | 0 | $0 | 0.00% | −425,269−100.0% | Sold out |
| UBS Asset Management Americas Inc | 0 | $0 | 0.00% | −353,508−100.0% | Sold out |
| Woodline Partners LP | 0 | $0 | 0.00% | −229,376−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −220,264−100.0% | Sold out |
| Stifel Financial Corp | 0 | $0 | 0.00% | −112,853−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −88,982−100.0% | Sold out |
| Teacher Retirement System of Texas | 0 | $0 | 0.00% | −65,415−100.0% | Sold out |
| Dimensional Fund Advisors LP | 0 | $0 | 0.00% | −64,966−100.0% | Sold out |
| Arizona State Retirement System | 0 | $0 | 0.00% | −62,976−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −51,141−100.0% | Sold out |
| Great West Life Assurance Co | 0 | $0 | 0.00% | −46,013−100.0% | Sold out |
| Rpo LLC | 0 | $0 | 0.00% | −44,242−100.0% | Sold out |
| Bayesian Capital Management, LP | 0 | $0 | 0.00% | −42,000−100.0% | Sold out |
| Kestra Advisory Services, LLC | 0 | $0 | 0.00% | −31,500−100.0% | Sold out |
| Manufacturers Life Insurance Company, The | 0 | $0 | 0.00% | −29,646−100.0% | Sold out |
| KLP Kapitalforvaltning AS | 0 | $0 | 0.00% | −26,200−100.0% | Sold out |
| State of Wisconsin Investment Board | 0 | $0 | 0.00% | −15,034−100.0% | Sold out |
| Vermillion & White Wealth Management Group, LLC | 0 | $0 | 0.00% | −13,415−100.0% | Sold out |
| Pinnacle Wealth Management Advisory Group, LLC | 0 | $0 | 0.00% | −12,445−100.0% | Sold out |
| Estabrook Capital Management | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Nordwand Advisors, LLC | 0 | $0 | 0.00% | −4,000−100.0% | Sold out |
| R Squared Ltd | 0 | $0 | 0.00% | −3,040−100.0% | Sold out |
| Manchester Capital Management LLC | 0 | $0 | 0.00% | −2,380−100.0% | Sold out |
| Signaturefd, LLC | 0 | $0 | 0.00% | −388−100.0% | Sold out |
| Coppell Advisory Solutions LLC | 0 | $0 | 0.00% | −52−100.0% | Sold out |
| Nuveen Asset Management, LLC | – | – | – | – | Not filed |
| Global Retirement Partners, LLC | – | – | – | – | Not filed |