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Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

13F holders, Q2 2022

Institutional positions in Lexicon Pharmaceuticals, Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
86
−12 vs. Q1 2022
Shares held
118.8M
−1.29M (−1.1%) vs. Q1 2022
Total value
$221.0M
−$30.1M (−12.0%) vs. Q1 2022
New holders
5
30 more added
Sold out
17
31 more reduced

3 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2022: 86 institutions
Q1 2021: 107 institutionsQ2 2021: 107 institutionsQ3 2021: 96 institutionsQ4 2021: 110 institutionsQ1 2022: 101 institutionsQ2 2022: 86 institutionsQ3 2022: 98 institutionsQ4 2022: 105 institutionsQ1 2023: 104 institutionsQ2 2023: 123 institutionsQ3 2023: 112 institutionsQ4 2023: 106 institutionsQ1 2024: 118 institutionsQ2 2024: 127 institutionsQ3 2024: 137 institutionsQ4 2024: 127 institutionsQ1 2025: 127 institutionsQ2 2025: 123 institutionsQ3 2025: 124 institutionsQ4 2025: 126 institutionsQ1 2026: 137 institutionsQ2 2026: 149 institutions
Value heldQ2 2022: $221.0M
Q1 2021: $711.5MQ2 2021: $540.2MQ3 2021: $583.0MQ4 2021: $478.9MQ1 2022: $251.3MQ2 2022: $221.0MQ3 2022: $357.3MQ4 2022: $280.5MQ1 2023: $353.8MQ2 2023: $438.2MQ3 2023: $205.8MQ4 2023: $279.8MQ1 2024: $417.8MQ2 2024: $471.0MQ3 2024: $453.1MQ4 2024: $220.1MQ1 2025: $122.5MQ2 2025: $242.9MQ3 2025: $344.4MQ4 2025: $299.5MQ1 2026: $504.5MQ2 2026: $875.1M
Institutions holding LXRX and their total value by quarter
QuarterHoldersValue
Q2 2026149$875.1M
Q1 2026137$504.5M
Q4 2025126$299.5M
Q3 2025124$344.4M
Q2 2025123$242.9M
Q1 2025127$122.5M
Q4 2024127$220.1M
Q3 2024137$453.1M
Q2 2024127$471.0M
Q1 2024118$417.8M
Q4 2023106$279.8M
Q3 2023112$205.8M
Q2 2023123$438.2M
Q1 2023104$353.8M
Q4 2022105$280.5M
Q3 202298$357.3M
Q2 202286$221.0M
Q1 2022101$251.3M
Q4 2021110$478.9M
Q3 202196$583.0M
Q2 2021107$540.2M
Q1 2021107$711.5M

Institutions, Q2 2022

Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q1 2022.

Institutions holding LXRX in Q2 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Northwestern Mutual Wealth Management Co500$1.00K0.00%00.0%Unchanged
Daiwa Securities Group Inc.434$1.00K0.00%00.0%Unchanged
Costello Asset Management, INC500$1.00K0.00%00.0%Unchanged
Avion Wealth407$1.00K0.00%00.0%Unchanged
Wells Fargo & Company1,327$2.00K0.00%−178,625−99.3%Reduced
Royal Bank of Canada920$2.00K0.00%−3,891−80.9%Reduced
Farmers & Merchants Investments Inc1,000$2.00K0.00%00.0%Unchanged
Hall Laurie J Trustee1,650$3.00K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.2,591$4.00K0.00%+109+4.4%Added
Quintet Private Bank (Europe) S.A.1,895$4.40K0.00%+1,895New
Simplex Trading, LLC4,069$7.00K0.00%−6,109−60.0%Reduced
Ameritas Investment Partners, Inc.5,367$9.00K0.00%00.0%Unchanged
Great West Life Assurance Co4,635$9.00K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)6,157$11.0K0.00%−10,108−62.1%Reduced
Amalgamated Bank9,924$18.0K0.00%+303+3.1%Added
Estabrook Capital Management10,000$18.6K0.00%00.0%Unchanged
Pegasus Asset Management, Inc.10,000$19.0K0.01%00.0%Unchanged
Berger Financial Group, Inc10,929$20.0K0.00%00.0%Unchanged
Janus Henderson Group PLC11,361$21.0K0.00%−454−3.8%Reduced
Victory Capital Management Inc11,560$22.0K0.00%−23−0.2%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)12,688$24.0K0.00%00.0%Unchanged
State of Wisconsin Investment Board14,568$27.0K0.00%−73,232−83.4%Reduced
BNP Paribas Arbitrage, SA16,103$30.0K0.00%−90,461−84.9%Reduced
Arizona State Retirement System16,216$30.0K0.00%+116+0.7%Added
Balyasny Asset Management LLC16,363$30.0K0.00%+16,363New
Allspring Global Investments Holdings, LLC17,024$31.0K0.00%−186,730−91.6%Reduced
Citigroup Inc16,553$31.0K0.00%+7,877+90.8%Added
Legal & General Group Plc18,848$35.0K0.00%+1,282+7.3%Added
ProShare Advisors LLC19,832$37.0K0.00%−8,703−30.5%Reduced
AXA S.A.20,900$38.9K0.00%00.0%Unchanged
LPL Financial LLC20,700$39.0K0.00%+9,700+88.2%Added
Commonwealth Equity Services, LLC24,576$45.0K0.00%+10,300+72.1%Added
Voya Investment Management LLC26,351$49.0K0.00%−4,629−14.9%Reduced
Wolverine Trading, LLC22,169$50.0K0.00%+22,169New
Invesco Ltd.28,523$53.0K0.00%−1,326−4.4%Reduced
State Board of Administration of Florida Retirement System29,400$55.0K0.00%+100.0%Added
Deutsche Bank AG33,092$61.0K0.00%−4,803−12.7%Reduced
New York State Common Retirement Fund33,342$62.0K0.00%−157−0.5%Reduced
American International Group, Inc.34,092$63.0K0.00%−665−1.9%Reduced
University of Texas/Texas Am Investment Managment Co35,714$66.0K0.03%00.0%Unchanged
SG Americas Securities, LLC35,467$66.0K0.00%+1,747+5.2%Added
Bank of America Corp38,310$71.0K0.00%−8,406−18.0%Reduced
Credit Suisse AG38,975$72.0K0.00%−4,175−9.7%Reduced
Alliancebernstein L.P.56,611$105.0K0.00%+6,200+12.3%Added
Salem Investment Counselors Inc73,000$136.0K0.01%00.0%Unchanged
Barclays PLC75,254$140.0K0.00%−7,983−9.6%Reduced
California State Teachers Retirement System81,225$151.0K0.00%+2,499+3.2%Added
Susquehanna International Group, LLP93,951$175.0K0.00%−21,956−18.9%Reduced
Group One Trading, L.P.94,600$176.0K0.01%+14,637+18.3%Added
Rhumbline Advisers97,470$181.0K0.00%+17,536+21.9%Added
Compagnie Lombard Odier SCmA98,000$182.0K0.00%+94,000+2,350.0%Added
Tudor Investment Corp Et Al105,106$195.0K0.01%−34,495−24.7%Reduced
Prudential Financial Inc124,508$232.0K0.00%−44,500−26.3%Reduced
Stifel Financial Corp139,377$259.0K0.00%+6,328+4.8%Added
Swiss National Bank140,800$262.0K0.00%00.0%Unchanged
Los Angeles Capital Management LLC144,269$268.0K0.00%+1,722+1.2%Added
Citadel Advisors LLC165,679$308.0K0.00%−286,133−63.3%Reduced
UBS Asset Management Americas Inc175,950$327.3K0.00%+92,076+109.8%Added
Price T Rowe Associates Inc197,441$367.0K0.00%+43,509+28.3%Added
Goldman Sachs Group Inc208,025$387.0K0.00%+25,354+13.9%Added
UBS Group AG212,153$395.0K0.00%+870.0%Added
Wellington Management Group LLP217,197$404.0K0.00%00.0%Unchanged
Millennium Management LLC217,948$405.0K0.00%−150,706−40.9%Reduced
Nomura Holdings Inc212,620$410.0K0.00%−421,018−66.4%Reduced
Nuveen Asset Management, LLC249,934$465.0K0.00%+6,054+2.5%Added
Russell Investments Group, Ltd.250,317$465.0K0.00%00.0%Unchanged
Parkman Healthcare Partners LLC250,000$465.0K0.17%+250,000New
Bank of New York Mellon Corp257,096$478.0K0.00%−27,514−9.7%Reduced
Integral Health Asset Management, LLC300,000$558.0K0.11%+300,000New
Gsa Capital Partners LLP371,598$691.0K0.10%+141,095+61.2%Added
Charles Schwab Investment Management Inc434,564$809.0K0.00%−66,564−13.3%Reduced
Morgan Stanley568,908$1.06M0.00%+382,326+204.9%Added
Fisher Asset Management, LLC605,528$1.13M0.00%+237,334+64.5%Added
Dimensional Fund Advisors LP664,788$1.24M0.00%−204,823−23.6%Reduced
Northern Trust Corp672,463$1.25M0.00%+12,057+1.8%Added
JPMorgan Chase & Co1,132,777$2.11M0.00%+3,456+0.3%Added
Geode Capital Management, LLC1,341,413$2.50M0.00%+83,549+6.6%Added
State Street Corp1,352,001$2.52M0.00%+27,616+2.1%Added
Pinnacle Associates Ltd2,087,463$3.88M0.08%−6,831−0.3%Reduced
NEA Management Company, LLC2,382,286$4.43M0.23%00.0%Unchanged
D. E. Shaw & Co., Inc.3,228,072$6.00M0.01%−6320.0%Reduced
Vanguard Group Inc3,921,970$7.29M0.00%−234,266−5.6%Reduced
BlackRock Inc.4,519,829$8.41M0.00%+74,077+1.7%Added
FMR LLC5,290,614$9.84M0.00%+650.0%Added
BVF Inc14,149,179$26.3M1.27%−207,410−1.4%Reduced
Artal Group S.A.71,178,364$132.4M7.36%00.0%Unchanged
HRT Financial LP0$00.00%−242,211−100.0%Sold out
Walleye Capital LLC0$00.00%−200,968−100.0%Sold out
Renaissance Technologies LLC0$00.00%−88,776−100.0%Sold out
Panagora Asset Management Inc0$00.00%−53,152−100.0%Sold out
Principal Financial Group Inc0$00.00%−51,855−100.0%Sold out
AQR Capital Management LLC0$00.00%−47,677−100.0%Sold out
Virtus ETF Advisers LLC0$00.00%−39,262−100.0%Sold out
Manufacturers Life Insurance Company, The0$00.00%−33,729−100.0%Sold out
Squarepoint Ops LLC0$00.00%−26,189−100.0%Sold out
Jane Street Group, LLC0$00.00%−19,723−100.0%Sold out
Parallax Volatility Advisers, L.P.0$00.00%−19,265−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−16,301−100.0%Sold out
Teacher Retirement System of Texas0$00.00%−12,393−100.0%Sold out
Bank of Montreal0$00.00%−12,000−100.0%Sold out