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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Fulcrum Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
122
+5 vs. Q1 2025
Shares held
54.4M
+3.03M (+5.9%) vs. Q1 2025
Total value
$374.5M
+$226.7M (+153.4%) vs. Q1 2025
New holders
24
34 more added
Sold out
19
46 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 122 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ2 2025: $374.5M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q1 2025.

Institutions holding FULC in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Connor, Clark & Lunn Investment Management Ltd.342,547$2.36M0.01%+124,798+57.3%Added
Charles Schwab Investment Management Inc387,782$2.67M0.00%+6,423+1.7%Added
Ikarian Capital, LLC428,521$2.95M0.98%+228,425+114.2%Added
Exome Asset Management LLC444,949$3.06M2.52%−244,188−35.4%Reduced
Invesco Ltd.470,333$3.24M0.00%+384,566+448.4%Added
Point72 Asset Management, L.P.498,219$3.43M0.01%+498,219New
Acadian Asset Management LLC563,380$3.87M0.01%+218,819+63.5%Added
Northern Trust Corp611,536$4.21M0.00%−29,411−4.6%Reduced
Woodline Partners LP897,617$6.18M0.03%00.0%Unchanged
Goldman Sachs Group Inc1,143,536$7.87M0.00%+740,936+184.0%Added
D. E. Shaw & Co., Inc.1,176,711$8.10M0.01%+596,050+102.7%Added
Geode Capital Management, LLC1,193,138$8.21M0.00%−38,237−3.1%Reduced
State Street Corp1,218,366$8.38M0.00%−34,074−2.7%Reduced
Balyasny Asset Management LLC1,338,214$9.21M0.02%+1,338,214New
Dimensional Fund Advisors LP1,372,637$9.44M0.00%−34,412−2.4%Reduced
Vanguard Group Inc3,146,443$21.6M0.00%−73,935−2.3%Reduced
Nantahala Capital Management, LLC4,288,299$29.5M2.09%−534,394−11.1%Reduced
BlackRock, Inc.4,379,023$30.1M0.00%−331,674−7.0%Reduced
Adage Capital Partners GP, L.L.C.4,589,000$31.6M0.05%+1,589,000+53.0%Added
Suvretta Capital Management, LLC5,082,900$35.0M1.32%+15,506+0.3%Added
TCG Crossover Management, LLC5,250,000$36.1M4.13%00.0%Unchanged
Ra Capital Management, L.P.10,229,099$70.4M1.19%00.0%Unchanged
Shay Capital LLC0$00.00%−224,305−100.0%Sold out
Verition Fund Management LLC0$00.00%−65,388−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−57,070−100.0%Sold out
HRT Financial LP0$00.00%−50,490−100.0%Sold out
XTX Topco Ltd0$00.00%−49,878−100.0%Sold out
Algert Global LLC0$00.00%−36,147−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−32,086−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−26,381−100.0%Sold out
SG Americas Securities, LLC0$00.00%−25,375−100.0%Sold out
Zacks Investment Management0$00.00%−20,999−100.0%Sold out
Virtu Financial LLC0$00.00%−13,564−100.0%Sold out
Jain Global LLC0$00.00%−13,051−100.0%Sold out
Engineers Gate Manager LP0$00.00%−12,519−100.0%Sold out
CIBC World Markets Corp0$00.00%−11,949−100.0%Sold out
Jump Financial, LLC0$00.00%−10,550−100.0%Sold out
Caitong International Asset Management Co., Ltd0$00.00%−1,507−100.0%Sold out
Steward Partners Investment Advisory, LLC0$00.00%−790−100.0%Sold out
UBS Asset Management Americas Inc0$00.00%−703−100.0%Sold out
Coldstream Capital Management Inc0$00.00%−105−100.0%Sold out