Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Definium Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 362
- +119 vs. Q1 2026
- Shares held
- 114.8M
- +40.3M (+54.1%) vs. Q1 2026
- Total value
- $5.35B
- +$3.94B (+280.1%) vs. Q1 2026
- New holders
- 148
- 117 more added
- Sold out
- 29
- 64 more reduced
5 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Stableford Capital II LLC | 27,141 | $1.28M | 0.44% | +27,141 | New |
| Mariner, LLC | 27,207 | $1.28M | 0.00% | −7,644−21.9% | Reduced |
| SG Americas Securities, LLC | 28,262 | $1.33M | 0.00% | +17,769+169.3% | Added |
| Vanguard Investments Australia, Ltd. | 28,265 | $1.33M | 0.00% | +7,798+38.1% | Added |
| Cinctive Capital Management LP | 28,550 | $1.34M | 0.05% | +15,999+127.5% | Added |
| SEI Investments Co | 28,582 | $1.34M | 0.00% | +465+1.7% | Added |
| Palumbo Wealth Management LLC | 29,287 | $1.38M | 0.29% | −8,679−22.9% | Reduced |
| Arizona State Retirement System | 30,411 | $1.43M | 0.01% | +8,357+37.9% | Added |
| State of New Jersey Common Pension Fund D | 30,625 | $1.44M | 0.00% | +3,184+11.6% | Added |
| Vestmark Advisory Solutions, Inc. | 30,729 | $1.45M | 0.01% | +30,729 | New |
| Bay Rivers Group | 31,208 | $1.47M | 0.50% | +4,862+18.5% | Added |
| Kingswood Wealth Advisors, LLC | 31,444 | $1.48M | 0.06% | +4,853+18.3% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 32,394 | $1.52M | 0.00% | +11,526+55.2% | Added |
| STRS Ohio | 33,500 | $1.58M | 0.01% | +14,200+73.6% | Added |
| TD Waterhouse Canada Inc. | 36,694 | $1.59M | 0.00% | +34,892+1,936.3% | Added |
| Scotia Capital Inc. | 34,722 | $1.64M | 0.01% | −5,826−14.4% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 38,386 | $1.81M | 0.01% | +11,025+40.3% | Added |
| Susquehanna International Group, LLP | 40,954 | $1.93M | 0.00% | −40,502−49.7% | Reduced |
| CenterBook Partners LP | 41,255 | $1.94M | 0.10% | −1,574−3.7% | Reduced |
| Ghisallo Capital Management LLC | 41,500 | $1.95M | 0.04% | +41,500 | New |
| Aquatic Capital Management LLC | 43,124 | $2.03M | 0.07% | +43,124 | New |
| Polymer Capital Management (HK) LTD | 44,100 | $2.07M | 0.21% | +44,100 | New |
| Caption Management, LLC | 45,000 | $2.12M | 0.07% | +11,242+33.3% | Added |
| Jennison Associates LLC | 45,375 | $2.13M | 0.00% | +5,418+13.6% | Added |
| Allstate Corp | 45,639 | $2.15M | 0.02% | +273+0.6% | Added |
| New York State Common Retirement Fund | 45,800 | $2.15M | 0.00% | +16,200+54.7% | Added |
| Simplex Trading, LLC | 47,651 | $2.24M | 0.06% | +6,495+15.8% | Added |
| Nisa Investment Advisors, LLC | 48,369 | $2.28M | 0.01% | −534−1.1% | Reduced |
| Atom Investors LP | 49,436 | $2.33M | 0.21% | +49,436 | New |
| Barclays PLC | 50,296 | $2.37M | 0.00% | +10,613+26.7% | Added |
| Kestra Private Wealth Services, LLC | 50,588 | $2.38M | 0.03% | 00.0% | Unchanged |
| Moody Aldrich Partners LLC | 51,025 | $2.40M | 0.43% | +51,025 | New |
| State of Wisconsin Investment Board | 52,549 | $2.47M | 0.00% | +2,129+4.2% | Added |
| Blair William & Co | 53,588 | $2.52M | 0.01% | −107−0.2% | Reduced |
| Cerity Partners LLC | 53,883 | $2.53M | 0.00% | +53,883 | New |
| Y-Intercept (Hong Kong) Ltd | 54,466 | $2.56M | 0.05% | +54,466 | New |
| Peak Financial Advisors LLC | 56,915 | $2.68M | 1.11% | +56,915 | New |
| Vanguard Global Advisers, LLC | 56,942 | $2.68M | 0.00% | +8,898+18.5% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 59,936 | $2.82M | 0.00% | +13,743+29.8% | Added |
| Algert Global LLC | 63,700 | $3.00M | 0.04% | +63,700 | New |
| Group One Trading, L.P. | 63,943 | $3.01M | 0.09% | −23,889−27.2% | Reduced |
| Platinum Investment Management Ltd | 70,000 | $3.29M | 0.81% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 70,111 | $3.30M | 0.01% | +14,905+27.0% | Added |
| Quantinno Capital Management LP | 70,682 | $3.32M | 0.00% | +30,724+76.9% | Added |
| Legal & General Group Plc | 74,004 | $3.48M | 0.00% | +14,205+23.8% | Added |
| MetLife Investment Management | 75,859 | $3.57M | 0.02% | +21,598+39.8% | Added |
| Sectoral Asset Management Inc | 78,310 | $3.68M | 2.57% | +78,310 | New |
| Vanguard Asset Management, Ltd | 78,604 | $3.70M | 0.00% | +24,586+45.5% | Added |
| Citigroup Inc | 79,547 | $3.74M | 0.00% | +53,061+200.3% | Added |
| Shay Capital LLC | 80,000 | $3.76M | 0.42% | +80,000 | New |
| Logos Global Management LP | 80,000 | $3.76M | 0.16% | +80,000 | New |
| XTX Topco Ltd | 84,393 | $3.97M | 0.05% | +84,393 | New |
| Squadron Capital Management LLC | 85,000 | $4.00M | 1.37% | +85,000 | New |
| LPL Financial LLC | 86,136 | $4.05M | 0.00% | +7,865+10.0% | Added |
| Pier Capital, LLC | 88,598 | $4.17M | 0.55% | +88,598 | New |
| Invesco Ltd. | 91,338 | $4.30M | 0.00% | +3,217+3.7% | Added |
| Keystone Investors Pte Ltd | 95,100 | $4.47M | 0.24% | +95,100 | New |
| Voya Investment Management LLC | 95,166 | $4.48M | 0.00% | +78,782+480.8% | Added |
| BNP Paribas Arbitrage, SA | 96,510 | $4.54M | 0.00% | +73,154+313.2% | Added |
| Burkehill Global Management, LP | 100,000 | $4.70M | 0.17% | 00.0% | Unchanged |
| Royal Bank of Canada | 100,063 | $4.71M | 0.00% | +2,871+3.0% | Added |
| Data Collective IV GP, LLC | 100,350 | $4.72M | 6.01% | 00.0% | Unchanged |
| Alps Advisors Inc | 110,388 | $5.19M | 0.02% | +110,388 | New |
| HSBC Holdings PLC | 117,482 | $5.53M | 0.00% | +117,482 | New |
| Schonfeld Strategic Advisors LLC | 119,610 | $5.63M | 0.03% | +109,198+1,048.8% | Added |
| EAM Investors, LLC | 120,928 | $5.69M | 0.51% | +120,928 | New |
| Emerald Mutual Fund Advisers Trust | 121,249 | $5.70M | 0.20% | +121,249 | New |
| AdvisorShares Investments LLC | 121,381 | $5.71M | 0.69% | +30,080+32.9% | Added |
| Atika Capital Management LLC | 122,000 | $5.74M | 0.57% | +122,000 | New |
| Wells Fargo & Company | 122,033 | $5.74M | 0.00% | +82,060+205.3% | Added |
| Fred Alger Management, LLC | 125,256 | $5.89M | 0.02% | +33,091+35.9% | Added |
| BIT Capital GmbH | 128,131 | $6.03M | 0.21% | −149,380−53.8% | Reduced |
| California State Teachers Retirement System | 128,346 | $6.04M | 0.01% | +128,346 | New |
| AQR Capital Management LLC | 134,152 | $6.31M | 0.00% | +77,058+135.0% | Added |
| StemPoint Capital LP | 137,124 | $6.45M | 1.12% | −188,359−57.9% | Reduced |
| SummitTX Capital, L.P. | 142,489 | $6.70M | 0.18% | +142,489 | New |
| Deutsche Bank AG | 142,947 | $6.72M | 0.00% | −268,887−65.3% | Reduced |
| Rock Springs Capital Management LP | 143,187 | $6.74M | 0.33% | +143,187 | New |
| Manufacturers Life Insurance Company, The | 146,368 | $6.89M | 0.01% | +119,964+454.3% | Added |
| Seven Fleet Capital Management LP | 148,647 | $6.99M | 1.15% | +48,760+48.8% | Added |
| LMR Partners LLP | 150,200 | $7.07M | 0.05% | +150,200 | New |
| Russell Investments Group, Ltd. | 153,477 | $7.22M | 0.01% | +34,013+28.5% | Added |
| Brevan Howard Capital Management LP | 156,812 | $7.38M | 0.10% | −54,676−25.9% | Reduced |
| Rhumbline Advisers | 158,096 | $7.44M | 0.01% | +38,124+31.8% | Added |
| Tri Locum Partners LP | 162,996 | $7.67M | 0.94% | −206,592−55.9% | Reduced |
| Bank of America Corp | 164,575 | $7.74M | 0.00% | +6,230+3.9% | Added |
| Standard Life Aberdeen plc | 175,000 | $8.23M | 0.01% | +175,000 | New |
| Emerald Advisers, LLC | 178,751 | $8.41M | 0.20% | +178,751 | New |
| Superstring Capital Management LP | 188,282 | $8.86M | 5.59% | −163,179−46.4% | Reduced |
| SEB Asset Management AB | 208,254 | $9.80M | 0.04% | +208,254 | New |
| Royce & Associates LP | 208,551 | $9.81M | 0.08% | −25,500−10.9% | Reduced |
| TD Asset Management Inc | 209,460 | $9.85M | 0.01% | +209,460 | New |
| UBS Asset Management Americas Inc | 211,183 | $9.93M | 0.00% | +208,770+8,651.9% | Added |
| Eversept Partners, LP | 217,185 | $10.2M | 0.56% | +56,462+35.1% | Added |
| Swiss National Bank | 221,200 | $10.4M | 0.01% | +62,800+39.6% | Added |
| Seven Grand Managers, LLC | 225,000 | $10.6M | 0.43% | 00.0% | Unchanged |
| Trexquant Investment LP | 233,199 | $11.0M | 0.07% | +233,199 | New |
| HighVista Strategies LLC | 242,884 | $11.4M | 2.60% | +57,028+30.7% | Added |
| PFM Health Sciences, LP | 249,020 | $11.7M | 1.02% | +43,703+21.3% | Added |
| Sofinnova Investments, Inc. | 255,903 | $12.0M | 0.64% | −88,263−25.6% | Reduced |